You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Yeast Metabolome Database.

Alanine, aspartate and glutamate metabolism

Source	ID	Pathway
KEGG	00250

Pathway Metabolites

YMDB ID	Name CAS Number	IUPAC Name	Formula Weight
YMDB00002	L-Glutamine 56-85-9	(2S)-2-amino-4-carbamoylbutanoic acid	C₅H₁₀N₂O₃ 146.1445
YMDB00012	Adenylsuccinic acid 19046-78-7	2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid	C₁₄H₁₈N₅O₁₁P 463.2934
YMDB00027	Ureidosuccinic acid 13184-27-5	(2S)-2-(carbamoylamino)butanedioic acid	C₅H₈N₂O₅ 176.1274
YMDB00044	Glucosamine 6-phosphate 3616-42-0	{[(2R,3S,4R,5R,6S)-5-amino-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid	C₆H₁₄NO₈P 259.151
YMDB00052	Argininosuccinic acid 2387-71-5	(2S)-2-{N'-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acid	C₁₀H₁₈N₄O₆ 290.2731
YMDB00067	5-Phosphoribosylamine 14050-66-9	{[(2R,3S,4R,5R)-5-amino-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid	C₅H₁₂NO₇P 229.125
YMDB00082	Carbamoylphosphate 590-55-6	(carbamoyloxy)phosphonic acid	CH₄NO₅P 141.0199
YMDB00091	Ammonia 7664-41-7	ammonia	H₃N 17.0305
YMDB00101	Fumaric acid 110-17-8	(2E)-but-2-enedioic acid	C₄H₄O₄ 116.0722
YMDB00153	Oxoglutaric acid 328-50-7	2-oxopentanedioic acid	C₅H₆O₅ 146.0981
YMDB00154	L-Alanine 56-41-7	(2S)-2-aminopropanoic acid	C₃H₇NO₂ 89.0932
YMDB00175	Pyruvic acid 127-17-3	2-oxopropanoic acid	C₃H₄O₃ 88.0621
YMDB00226	L-Asparagine 70-47-3	(2S)-2-amino-3-carbamoylpropanoic acid	C₄H₈N₂O₃ 132.1179
YMDB00235	Oxalacetic acid 328-42-7	2-oxobutanedioic acid	C₄H₄O₅ 132.0716
YMDB00236	Succinic acid semialdehyde 692-29-5	4-oxobutanoic acid	C₄H₆O₃ 102.0886
YMDB00243	1-Pyrroline-5-carboxylic acid 2906-39-0	3,4-dihydro-2H-pyrrole-2-carboxylic acid	C₅H₇NO₂ 113.1146
YMDB00271	L-Glutamic acid 56-86-0	(2S)-2-aminopentanedioic acid	C₅H₉NO₄ 147.1293
YMDB00335	gamma-Aminobutyric acid 56-12-2	4-aminobutanoic acid	C₄H₉NO₂ 103.1198
YMDB00338	Succinic acid 110-15-6	butanedioic acid	C₄H₆O₄ 118.088
YMDB00419	1-Pyrroline-5-carboxylate		C₅H₆NO₂ 112.1066
YMDB00593	(N(omega)-L-arginino)succinic acid 2387-71-5	2-{3-[(4S)-4-amino-4-carboxybutyl]carbamimidamido}butanedioic acid	C₁₀H₁₈N₄O₆ 290.2731
YMDB00871	N6-(1,2-Dicarboxyethyl)-AMP 19046-78-7	(2S)-2-({9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid	C₁₄H₁₈N₅O₁₁P 463.2934
YMDB00874	2-oxoglutaramic acid 18465-19-5		C₅H₇NO₄ 145.1134
YMDB00896	L-Aspartic acid 56-84-8	(2S)-2-aminobutanedioic acid	C₄H₇NO₄ 133.1027
YMDB00992	succinate semialdehyde 692-29-5		C₄H₆O₃ 102.0886
YMDB01008	N-Carbamoyl-L-aspartate 13184-27-5		C₅H₆N₂O₅ 174.1115
YMDB01038	fumarate(2-) 110-17-8		C₄H₂O₄ 114.0563
YMDB01053	pyruvate 127-17-3		C₃H₃O₃ 87.0541

Pathway Proteins

Uniprot ID	Gene Name Locus	Name	Type	Metabolites
A2P2R3	YMR084W	Putative glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	Enzyme	L-Glutamine Glucosamine 6-phosphate Fructose 6-phosphate L-Glutamic acid
P14742	GFA1 YKL104C	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	Enzyme	L-Glutamine Glucosamine 6-phosphate Fructose 6-phosphate L-Glutamic acid Beta-D-Fructose 6-phosphate
P07258	CPA1 YOR303W	Carbamoyl-phosphate synthase arginine-specific small chain	Enzyme	L-Glutamine Carbamoylphosphate Adenosine triphosphate L-Glutamic acid Carbonic acid phosphate ADP
P07259	URA2 YJL130C	Protein URA1	Enzyme	L-Glutamine Ureidosuccinic acid Carbamoylphosphate Adenosine triphosphate L-Glutamic acid Carbonic acid hydron water L-Aspartic acid phosphate ADP N-Carbamoyl-L-aspartate Hydrogen carbonate
P03965	CPA2 YJR109C	Carbamoyl-phosphate synthase arginine-specific large chain	Enzyme	L-Glutamine Carbamoylphosphate Adenosine triphosphate L-Glutamic acid Carbonic acid hydron water phosphate ADP
P32288	GLN1 YPR035W	Glutamine synthetase	Enzyme	L-Glutamine Ammonia Adenosine triphosphate L-Glutamic acid Ammonium hydron phosphate ADP
P49089	ASN1 YPR145W	Asparagine synthetase [glutamine-hydrolyzing] 1	Enzyme	L-Glutamine Adenosine monophosphate Adenosine triphosphate Pyrophosphate L-Asparagine L-Glutamic acid Ammonium hydron water L-Aspartic acid
Q12680	GLT1 YDL171C	Glutamate synthase [NADH]	Enzyme	L-Glutamine NAD NADH Oxoglutaric acid L-Glutamic acid NAD(+) hydron
P49090	ASN2 YGR124W	Asparagine synthetase [glutamine-hydrolyzing] 2	Enzyme	L-Glutamine Adenosine monophosphate Adenosine triphosphate Pyrophosphate L-Asparagine L-Glutamic acid Ammonium hydron water L-Aspartic acid
P04046	ADE4 YMR300C	Amidophosphoribosyltransferase	Enzyme	L-Glutamine 5-Phosphoribosylamine Pyrophosphate L-Glutamic acid Phosphoribosyl pyrophosphate water
P80210	ADE12 YNL220W	Adenylosuccinate synthetase	Enzyme	Adenylsuccinic acid Guanosine diphosphate Inosinic acid GTP hydron L-Aspartic acid phosphate
Q05911	ADE13 YLR359W	Adenylosuccinate lyase	Enzyme	Adenylsuccinic acid Adenosine monophosphate Fumaric acid Phosphoribosyl formamidocarboxamide SAICAR (2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid 5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide N6-(1,2-Dicarboxyethyl)-AMP
P43567	AGX1 YFL030W	Alanine--glyoxylate aminotransferase 1	Enzyme	Glycine Glyoxylic acid L-Alanine Pyruvic acid
P22768	ARG1 YOL058W	Argininosuccinate synthase	Enzyme	Argininosuccinic acid Citrulline Adenosine monophosphate Adenosine triphosphate Pyrophosphate (N(omega)-L-arginino)succinic acid hydron L-Aspartic acid
P04076	ARG4 YHR018C	Argininosuccinate lyase	Enzyme	Argininosuccinic acid Fumaric acid L-Arginine (N(omega)-L-arginino)succinic acid
P33327	GDH2 YDL215C	NAD-specific glutamate dehydrogenase	Enzyme	Ammonia NAD NADH Oxoglutaric acid L-Glutamic acid NAD(+) Ammonium hydron water
P11163	ASP3-1 YLR155C	L-asparaginase 2	Enzyme	Ammonia L-Asparagine Ammonium water L-Aspartic acid
P39708	GDH3 YAL062W	NADP-specific glutamate dehydrogenase 2	Enzyme	Ammonia Oxoglutaric acid L-Glutamic acid Ammonium NADPH NADP hydron water
P38986	ASP1 YDR321W	L-asparaginase 1	Enzyme	Ammonia L-Asparagine Ammonium water L-Aspartic acid
P07262	GDH1 YOR375C	NADP-specific glutamate dehydrogenase 1	Enzyme	Ammonia Oxoglutaric acid L-Glutamic acid Ammonium NADPH NADP hydron water
P07275	PUT2 YHR037W	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	Enzyme	NAD NADH Succinic acid semialdehyde 1-Pyrroline-5-carboxylic acid L-Glutamic acid Succinic acid NAD(+) NADPH NADP 1-pyrroline-3-hydroxy-5-carboxylic acid erythro-4-hydroxy-L-glutamic acid L-4-hydroxyglutamic semialdehyde trans-4-hydroxy-L-proline hydron water l-Glutamic-gamma-semialdehyde
Q01802	AAT1 YKL106W	Aspartate aminotransferase, mitochondrial	Enzyme	Oxoglutaric acid Oxalacetic acid L-Glutamic acid L-Tyrosine erythro-4-hydroxy-L-glutamic acid 4-hydroxy-2-oxoglutaric acid L-Aspartic acid (4-hydroxyphenyl)pyruvic acid
P23542	AAT2 YLR027C	Aspartate aminotransferase, cytoplasmic	Enzyme	Oxoglutaric acid Oxalacetic acid L-Glutamic acid L-Tyrosine erythro-4-hydroxy-L-glutamic acid 4-hydroxy-2-oxoglutaric acid L-Aspartic acid (4-hydroxyphenyl)pyruvic acid
P52892	ALT2 YDR111C	Probable alanine aminotransferase	Enzyme	Oxoglutaric acid L-Alanine Pyruvic acid L-Glutamic acid
P17649	UGA1 YGR019W	4-aminobutyrate aminotransferase	Enzyme	Oxoglutaric acid Succinic acid semialdehyde L-Glutamic acid gamma-Aminobutyric acid 4-(Glutamylamino) butanoate
P52893	ALT1 YLR089C	Probable alanine aminotransferase, mitochondrial	Enzyme	Oxoglutaric acid L-Alanine Pyruvic acid L-Glutamic acid
P38067	UGA2 YBR006W	Succinate-semialdehyde dehydrogenase [NADP+]	Enzyme	Succinic acid semialdehyde Succinic acid NADPH NADP hydron water succinate semialdehyde
Q04792	GAD1 YMR250W	Glutamate decarboxylase	Enzyme	Beta-Alanine L-Glutamic acid gamma-Aminobutyric acid Taurine hydron L-Aspartic acid Carbon dioxide Hypotaurine 3-Sulfinoalanine Cysteic acid 4-(Glutamylamino) butanoate