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Identification |
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YMDB ID | YMDB00896 |
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Name | L-Aspartic acid |
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Species | Saccharomyces cerevisiae |
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Strain | Baker's yeast |
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Description | Aspartate (abbreviated as Asp or D) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a polar, acidic (pKa = 4.0) amino acid with a side chain carboxylic acid. Aspartate is the precursor to several amino acids, including methionine, threonine, isoleucine, and lysine. The conversion of aspartate to these other amino acids begins with reduction of aspartate to its 'semialdehyde'. Asparagine is derived from aspartate via transamidation. Aspartate is also a metabolite in the urea cycle and participates in gluconeogenesis. It carries reducing equivalents in the malate-aspartate shuttle, which utilizes the ready interconversion of aspartate and oxaloacetate, which is the oxidized (dehydrogenated) derivative of malic acid. Aspartate donates one nitrogen atom in the biosynthesis of inosine, the precursor to the purine bases. |
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Structure | |
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Synonyms | - (+)-Aspartate
- (+)-Aspartic acid
- (2S)-2-ammoniobutanedioate
- (2S)-2-ammoniosuccinate
- (2S)-Aspartate
- (2S)-Aspartic acid
- (L)-Aspartate
- (L)-Aspartic acid
- (R)-2-aminosuccinate
- (S)-(+)-Aspartate
- (S)-(+)-Aspartic acid
- (S)-2-aminosuccinate
- (S)-2-aminosuccinic acid
- (S)-amino-Butanedioate
- (S)-amino-Butanedioic acid
- (S)-Aminobutanedioate
- (S)-Aminobutanedioic acid
- (S)-Aspartate
- (S)-Aspartic acid
- 2-Amino-3-methylsuccinate
- 2-Amino-3-methylsuccinic acid
- 2-Aminosuccinate
- 2-Aminosuccinic acid
- Acidum asparticum
- alpha-Aminosuccinate
- alpha-Aminosuccinic acid
- Aminosuccinate
- Aminosuccinic acid
- Asp
- Asparagate
- Asparagic acid
- Asparaginate
- Asparaginic acid
- Asparatate
- Aspartate
- Aspartic acid
- Aspartic acid, L-
- Aspatofort
- Butanedioic acid, amino-, (S)-
- H-Asp-OH
- L-(+ )-Aspartic acid
- L-(+)-Aspartate
- L-(+)-Aspartic acid
- L-2-Aminobutanedioic acid
- L-Aminosuccinate
- L-Aminosuccinic acid
- L-Asp
- L-Asparagate
- L-Asparagic acid
- L-Asparaginate
- L-Asparaginic acid
- L-Asparaginsaeure
- L-Asparaginsyra
- L-Aspartate
- L-aspartate(1-)
- L-Aspartic acid
- L-aspartic acid monoanion
- L-Aspartinsaeure
- (S)-2-Aminobutanedioic acid
- D
- (S)-2-Aminobutanedioate
- (+-)-Aspartic acid
- (R,S)-Aspartic acid
- Aspartate, disodium
- Aspartate, magnesium
- Aspartate, monopotassium
- Aspartic acid, dipotassium salt
- Aspartic acid, hydrobromide
- Aspartic acid, monopotassium salt
- Aspartic acid, monosodium salt
- Aspartic acid, potassium salt
- L Aspartate
- MG5Longoral
- Potassium aspartate
- Polysuccinimide
- Ammonium aspartate
- Aspartate, ammonium
- Aspartate, calcium
- Aspartate, monosodium
- Aspartic acid, calcium salt
- Aspartic acid, disodium salt
- Aspartic acid, magnesium (1:1) salt, hydrochloride, trihydrate
- Dipotassium aspartate
- Disodium aspartate
- Hydrochloride, aspartate magnesium
- Monopotassium aspartate
- Sodium aspartate
- Aspartate, dipotassium
- Aspartic acid, magnesium (2:1) salt
- Aspartic acid, sodium salt
- Hydrobromide aspartic acid
- Magnesium aspartate
- MG 5 Longoral
- Monosodium aspartate
- Aspartate magnesium hydrochloride
- Aspartate, potassium
- Aspartate, sodium
- Aspartic acid, ammonium salt
- Aspartic acid, hydrochloride
- Aspartic acid, magnesium-potassium (2:1:2) salt
- Calcium aspartate
- Hydrochloride aspartic acid
- L Aspartic acid
- Magnesiocard
- MG-5-Longoral
- Poly-DL-succinimide
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CAS number | 56-84-8 |
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Weight | Average: 133.1027 Monoisotopic: 133.037507717 |
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InChI Key | CKLJMWTZIZZHCS-REOHCLBHSA-N |
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InChI | InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1 |
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IUPAC Name | (2S)-2-aminobutanedioic acid |
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Traditional IUPAC Name | L-aspartic acid |
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Chemical Formula | C4H7NO4 |
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SMILES | N[C@@H](CC(O)=O)C(O)=O |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as aspartic acid and derivatives. Aspartic acid and derivatives are compounds containing an aspartic acid or a derivative thereof resulting from reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Carboxylic acids and derivatives |
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Sub Class | Amino acids, peptides, and analogues |
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Direct Parent | Aspartic acid and derivatives |
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Alternative Parents | |
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Substituents | - Aspartic acid or derivatives
- Alpha-amino acid
- L-alpha-amino acid
- Dicarboxylic acid or derivatives
- Fatty acid
- Amino acid
- Carboxylic acid
- Organic oxide
- Organopnictogen compound
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Primary aliphatic amine
- Organic oxygen compound
- Carbonyl group
- Amine
- Organic nitrogen compound
- Hydrocarbon derivative
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State | Solid |
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Charge | 0 |
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Melting point | 270 °C |
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Experimental Properties | Property | Value | Reference |
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Water Solubility | 5.36 mg/mL at 25 oC [YALKOWSKY,SH & HE,Y (2003)] | PhysProp | LogP | -3.89 [CHMELIK,J ET AL. (1991)] | PhysProp |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations | - extracellular
- mitochondrion
- peroxisome
- vacuole
- cytoplasm
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Organoleptic Properties | |
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SMPDB Pathways |
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KEGG Pathways | Alanine, aspartate and glutamate metabolism | ec00250 | | Arginine and proline metabolism | ec00330 | | Cyanoamino acid metabolism | ec00460 | | Cysteine and methionine metabolism | ec00270 | | Glycine, serine and threonine metabolism | ec00260 | |
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SMPDB Reactions |
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KEGG Reactions |
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Concentrations |
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Intracellular Concentrations | Intracellular Concentration | Substrate | Growth Conditions | Strain | Citation |
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2096 ± 42 µM | YPD media | aerobic | Baker's yeast | PMID: 7654310 | 2096 ± 42 µM | YPG media | aerobic | Baker's yeast | PMID: 7654310 | 621 ± 12 µM | SD media | aerobic | Baker's yeast | PMID: 7654310 | 1164 ± 23 µM | SG media | aerobic | Baker's yeast | PMID: 7654310 | 539 ± 11 µM | M (molasses) | aerobic | Baker's yeast | PMID: 7654310 | 2466 ± 49 µM | MA (molasses) | aerobic | Baker's yeast | PMID: 7654310 | 694 ± 14 µM | MB (molasses) | aerobic | Baker's yeast | PMID: 7654310 | 3313 ± 66 µM | MAB (molasses) | aerobic | Baker's yeast | PMID: 7654310 | 1034 ± 52 µM | YEB media with 0.5 mM glucose | aerobic | Baker's yeast | Experimentally Determined Not Available | 8120 ± 2006 µM | Synthetic medium with 20 g/L glucose | aerobic | Baker's yeast | PMID: 12584756 | 8000 ± 5000 µM | Minimal medium supplemented with glucose | aerobic;resting cells | Baker's yeast | PMID: 4578278 | 8000 ± 5000 µM | Minimal medium supplemented with ammonium and glucose | aerobic;growing cells | Baker's yeast | PMID: 4578278 | Conversion Details Here |
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Extracellular Concentrations | Intracellular Concentration | Substrate | Growth Conditions | Strain | Citation |
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1202 ± 0 µM | hops, malted barley | anaerobic | Baker's yeast | Alcoholic beverage, beer, regular, all - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page | Conversion Details Here |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-0f89-0960000000-5a6a6cb21e9fc0875f84 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-0f89-0950000000-51399a8446c394459765 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-0f89-0950000000-f07e7f52b3c31fd119f5 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-0f89-0950000000-9e175dfa17a8b17a72d2 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized) | splash10-0f89-0950000000-f4475587d5a3b20bfc58 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS) | splash10-00di-9430000000-0cac9a97e698db1672b5 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (2 TMS) | splash10-03yi-1900000000-ea61b8526ee02ae79b66 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (3 TMS) | splash10-0f89-1890000000-7da576c8129142b71a1b | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (4 TMS) | splash10-0pb9-0981000000-ad23d55e348f55115f00 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - EI-B (Non-derivatized) | splash10-001i-0590000000-13cc5a7841854e97f68b | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f89-0960000000-5a6a6cb21e9fc0875f84 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f89-0950000000-51399a8446c394459765 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f89-0950000000-f07e7f52b3c31fd119f5 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f89-0950000000-9e175dfa17a8b17a72d2 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f89-0950000000-f4475587d5a3b20bfc58 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-QQ (Non-derivatized) | splash10-0g4i-6946100000-0ae49e3be0f2f1f92065 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-00di-9430000000-0cac9a97e698db1672b5 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-03yi-1900000000-ea61b8526ee02ae79b66 | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0f89-1890000000-7da576c8129142b71a1b | JSpectraViewer | MoNA | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0pb9-0981000000-ad23d55e348f55115f00 | JSpectraViewer | MoNA | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-000f-9100000000-b7db3377089f4c95001b | JSpectraViewer | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive | splash10-01w4-9610000000-0f1463c6395830708e12 | JSpectraViewer | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | JSpectraViewer | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_1_1) - 70eV, Positive | Not Available | JSpectraViewer | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, Positive | Not Available | JSpectraViewer | LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated) | splash10-0079-9300000000-92f9914d94078d96f5cf | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated) | splash10-00di-9000000000-c467d10f2b7e21ed1734 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated) | splash10-00dl-9000000000-87f0c58226f5a2f3ac8a | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-00di-0900000000-fde7ef1951fddff4b817 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-0uk9-8900000000-2d7e5609618437e59272 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-000i-9000000000-4b43567f4a446aed0828 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-014i-4900000000-45382d9abd25be948e5b | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-001i-0900000000-3f39a9b758e282358ac0 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-014i-3900000000-44d361ad09ff9a30dd14 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-000i-9000000000-18e1dba62e6b803e17b8 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive | splash10-0002-0930000000-d97f9518a2d516d830c5 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-02ai-0962100000-909bb894b2c1318afee4 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-00di-9000000000-f2059dd438fcf62f62e1 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-03dr-7900000000-8b7b89ed34530e331024 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-014i-0190000000-58a78949f4b93de22aab | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-001i-0921000000-214b6b969fdc4216ca71 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-03dr-6900000000-4918748927dd097d2879 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-001i-0900000000-88dc2f1093f261e76201 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative | splash10-004i-0290000000-a8856f56645a2961baac | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative | splash10-001i-0900000000-8cf9870557ca9adc3374 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative | splash10-000i-9400000000-81b2804a712625a2d9c4 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative | splash10-000i-9000000000-9bf77ba12ad952f84ac0 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative | splash10-00di-9000000000-e08bfb96c5fd8c9b9db7 | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative | splash10-0006-9000000000-876e30f6c9ed061091fe | JSpectraViewer | MoNA | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive | splash10-00dl-9000000000-6c0d44d4e3853e5701a3 | JSpectraViewer | MoNA | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 1H NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 1D NMR | 13C NMR Spectrum | Not Available | JSpectraViewer | 2D NMR | [1H,1H] 2D NMR Spectrum | Not Available | JSpectraViewer | 2D NMR | [1H,13C] 2D NMR Spectrum | Not Available | JSpectraViewer |
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References |
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References: | - Martinez-Force, E., Benitez, T. (1995). "Effects of varying media, temperature, and growth rates on the intracellular concentrations of yeast amino acids." Biotechnol Prog 11:386-392.7654310
- UniProt Consortium (2011). "Ongoing and future developments at the Universal Protein Resource." Nucleic Acids Res 39:D214-D219.21051339
- Scheer, M., Grote, A., Chang, A., Schomburg, I., Munaretto, C., Rother, M., Sohngen, C., Stelzer, M., Thiele, J., Schomburg, D. (2011). "BRENDA, the enzyme information system in 2011." Nucleic Acids Res 39:D670-D676.21062828
- Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., Bluthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novere, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasic, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttila, M., Klipp, E., Palsson, B. O., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., Kell, D. B. (2008). "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology." Nat Biotechnol 26:1155-1160.18846089
- Arevalo-Rodriguez, M., Calderon, I. L., Holmberg, S. (1999). "Mutations that cause threonine sensitivity identify catalytic and regulatory regions of the aspartate kinase of Saccharomyces cerevisiae." Yeast 15:1331-1345.10509015
- Alcoholic beverage, beer, regular, all - U.S. Department of Agriculture, Agricultural Research Service. 2010. USDA National Nutrient Database for Standard Reference, Release 23. Nutrient Data Laboratory Home Page
- Cavero, S., Vozza, A., del Arco, A., Palmieri, L., Villa, A., Blanco, E., Runswick, M. J., Walker, J. E., Cerdan, S., Palmieri, F., Satrustegui, J. (2003). "Identification and metabolic role of the mitochondrial aspartate-glutamate transporter in Saccharomyces cerevisiae." Mol Microbiol 50:1257-1269.14622413
- Verleur, N., Elgersma, Y., Van Roermund, C. W., Tabak, H. F., Wanders, R. J. (1997). "Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae." Eur J Biochem 247:972-980.9288922
- Nookaew, I., Jewett, M. C., Meechai, A., Thammarongtham, C., Laoteng, K., Cheevadhanarak, S., Nielsen, J., Bhumiratana, S. (2008). "The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism." BMC Syst Biol 2:71.18687109
- Gancedo, J. M., Gancedo, C. (1973). "Concentrations of intermediary metabolites in yeast." Biochimie 55:205-211.4578278
- Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., Cornell, M. J., Petty, J., Hakes, L., Wardleworth, L., Rash, B., Brown, M., Dunn, W. B., Broadhurst, D., O'Donoghue, K., Hester, S. S., Dunkley, T. P., Hart, S. R., Swainston, N., Li, P., Gaskell, S. J., Paton, N. W., Lilley, K. S., Kell, D. B., Oliver, S. G. (2007). "Growth control of the eukaryote cell: a systems biology study in yeast." J Biol 6:4.17439666
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Synthesis Reference: | Pamfil, Maria; Lupescu, Irina; Savoiu, Valeria Gabriela. L-aspartic acid production from fumarate using Escherichia coli whole cells. Rom. (2005), 3pp. |
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