You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Yeast Metabolome Database.
Identification |
---|
Name | Alanine--glyoxylate aminotransferase 1 |
---|
Synonyms | Not Available |
---|
Gene Name | AGX1 |
---|
Enzyme Class | |
---|
Biological Properties |
---|
General Function | Involved in metabolic process |
---|
Specific Function | Has alanine:glyoxylate aminotransferase activity |
---|
Cellular Location | Not Available |
---|
SMPDB Pathways | |
---|
KEGG Pathways | Alanine, aspartate and glutamate metabolism | ec00250 | | Glycine, serine and threonine metabolism | ec00260 | |
|
---|
SMPDB Reactions | |
---|
KEGG Reactions | |
---|
Metabolites | YMDB ID | Name | View |
---|
YMDB00016 | Glycine | Show | YMDB00033 | Glyoxylic acid | Show | YMDB00154 | L-Alanine | Show | YMDB00175 | Pyruvic acid | Show |
|
---|
GO Classification | Component |
---|
Not Available | Function |
---|
catalytic activity | binding | cofactor binding | pyridoxal phosphate binding | Process |
---|
metabolic process |
|
---|
Gene Properties |
---|
Chromosome Location | chromosome 6 |
---|
Locus | YFL030W |
---|
Gene Sequence | >1158 bp
ATGACTAAATCTGTAGATACGCTGCTGATCCCAGGCCCCATTATCCTAAGCGGAGCAGTC
CAGAAGGCCCTGGACGTTCCCTCTTTGGGCCACACCTCTCCTGAGTTCGTCTCTATTTTT
CAAAGGGTGCTAAAGAACACAAGAGCTGTCTTCAAATCCGCTGCTGCCTCGAAGTCTCAG
CCTTTTGTGCTTGCCGGCTCTGGTACGTTGGGGTGGGACATATTTGCCTCGAACTTTATT
CTTTCGAAGGCCCCCAACAAGAACGTGCTGGTCGTATCCACTGGGACATTTTCTGACAGG
TTTGCTGACTGTCTGCGTAGCTACGGTGCGCAAGTAGATGTTGTTAGGCCCCTCAAGATA
GGCGAATCAGTTCCCTTAGAACTGATTACTGAAAAGTTGTCGCAAAATAGCTATGGGGCT
GTCACGGTTACGCACGTTGACACTTCAACGGCAGTGCTGTCCGATCTGAAAGCCATTTCG
CAAGCGATTAAGCAGACTTCGCCGGAAACGTTCTTCGTAGTCGATGCTGTATGCTCGATT
GGATGCGAAGAGTTTGAATTTGATGAATGGGGGGTGGATTTCGCCTTGACTGCTTCGCAA
AAGGCTATTGGCGCTCCAGCGGGTCTTTCTATCTCGCTATGCAGTAGCAGATTCATGGAT
TATGCACTCAACGACAGCAAAAATGGTCATGTACATGGGTATTTTTCCTCGTTGAGAAGA
TGGACACCAATAATGGAAAATTATGAGGCTGGTAAAGGAGCTTATTTTGCAACCCCACCC
GTACAACTAATTAATAGCCTTGATGTAGCCTTGAAAGAAATTCTCGAAGAGGGGTTGCAT
AAGAGATGGGATTTGCACCGTGAAATGAGTGATTGGTTTAAAGACAGTTTGGTTAATGGC
TTGCAATTGACATCCGTCAGTAGGTATCCTTCTAACATGTCTGCGCACGGGTTGACAGCC
GTATACGTAGCAGATCCTCCTGATGTCATTGCTTTTTTAAAGTCACACGGTGTAGTCATT
GCCGGAGGTATTCACAAGGACATCGGACCCAAGTATATCCGTATTGGACATATGGGTGTG
ACCGCTTGCAACAAGAATTTACCGTACATGAAGAACTGCTTCGACTTAATAAAACTAGCT
CTTCAGAGGAAAAAGTGA |
---|
Protein Properties |
---|
Pfam Domain Function | |
---|
Protein Residues | 385 |
---|
Protein Molecular Weight | 41906.80078 |
---|
Protein Theoretical pI | 8.14 |
---|
Signalling Regions | |
---|
Transmembrane Regions | |
---|
Protein Sequence | >Alanine--glyoxylate aminotransferase 1
MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQ
PFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKI
GESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSDLKAISQAIKQTSPETFFVVDAVCSI
GCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRR
WTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVNG
LQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHGVVIAGGIHKDIGPKYIRIGHMGV
TACNKNLPYMKNCFDLIKLALQRKK |
---|
References |
---|
External Links | |
---|
General Reference | - Murakami, Y., Naitou, M., Hagiwara, H., Shibata, T., Ozawa, M., Sasanuma, S., Sasanuma, M., Tsuchiya, Y., Soeda, E., Yokoyama, K., et, a. l. .. (1995). "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Nat Genet 10:261-268.7670463
- Takada, Y., Noguchi, T. (1985). "Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates." Biochem J 231:157-163.3933486
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
- Schlosser, T., Gatgens, C., Weber, U., Stahmann, K. P. (2004). "Alanine : glyoxylate aminotransferase of Saccharomyces cerevisiae-encoding gene AGX1 and metabolic significance." Yeast 21:63-73.14745783
- Meyer, P., Liger, D., Leulliot, N., Quevillon-Cheruel, S., Zhou, C. Z., Borel, F., Ferrer, J. L., Poupon, A., Janin, J., van Tilbeurgh, H. (2005). "Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein." Biochimie 87:1041-1047.16226833
|
---|