You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Yeast Metabolome Database.

Terpenoid backbone biosynthesis

SourceIDPathway
PathWhizPW002485 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG00900 Map00900

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00045Coenzyme A
85-61-0
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534
Thumb
YMDB00095Dimethylallylpyrophosphate
358-72-5
({hydroxy[(3-methylbut-2-en-1-yl)oxy]phosphoryl}oxy)phosphonic acidC5H12O7P2
246.0921
Thumb
YMDB00109Adenosine triphosphate
56-65-5
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O13P3
507.181
Thumb
YMDB00115D-Glyceraldehyde 3-phosphate
142-10-9
(2-hydroxy-3-oxopropoxy)phosphonic acidC3H7O6P
170.0578
Thumb
YMDB00175Pyruvic acid
127-17-3
2-oxopropanoic acidC3H4O3
88.0621
Thumb
YMDB00181Mevalonic acid-5P
73566-35-5
(3R)-3-hydroxy-3-methyl-5-(phosphonooxy)pentanoic acidC6H13O7P
228.137
Thumb
YMDB00200Isopentenyl pyrophosphate
358-71-4
({hydroxy[(3-methylbut-3-en-1-yl)oxy]phosphoryl}oxy)phosphonic acidC5H12O7P2
246.0921
Thumb
YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
Thumb
YMDB00222di-trans,poly-cis-undecaprenyl diphosphate
31867-59-1
{[hydroxy({[(2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC55H92O7P2
927.2623
Thumb
YMDB00229Farnesyl pyrophosphate
13058-04-3
{[hydroxy({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy})phosphoryl]oxy}phosphonic acidC15H28O7P2
382.3261
Thumb
YMDB00266Geranyl-PP
763-10-0
[({[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H20O7P2
314.2091
Thumb
YMDB00312Acetyl-CoA
72-89-9
{[(2R,3S,4R,5R)-2-({[({[(3R)-3-[(2-{[2-(acetylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC23H38N7O17P3S
809.571
Thumb
YMDB003252-trans,6-trans-farnesyl diphosphate
13058-04-3
{[hydroxy({[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy})phosphoryl]oxy}phosphonic acidC15H28O7P2
382.3261
Thumb
YMDB003592-trans,6-trans,10-trans-geranylgeranyl diphosphate
6699-20-3
{[hydroxy({[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC20H36O7P2
450.4432
Thumb
YMDB004035-Diphosphomevalonic acid
4872-34-8
(3R)-3-hydroxy-5-{[hydroxy(phosphonooxy)phosphoryl]oxy}-3-methylpentanoic acidC6H14O10P2
308.1169
Thumb
YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
Thumb
YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129
Thumb
YMDB00529acetoacetyl-CoA
1420-36-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC25H40N7O18P3S
851.607
Thumb
YMDB00614nonaprenyl diphosphate{[hydroxy({[(2Z,6Z,10Z,14Z,18Z,22Z,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC45H76O7P2
791.0283
Thumb
YMDB00631geranylgeranyl diphosphate
6699-20-3
{[hydroxy({[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC20H36O7P2
450.4432
Thumb
YMDB00633hexaprenyl diphosphate[({[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC30H52O7P2
586.6772
Thumb
YMDB00634heptaprenyl diphosphate[({[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC35H60O7P2
654.7942
Thumb
YMDB00635octaprenyl diphosphate{[hydroxy({[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC40H68O7P2
722.9112
Thumb
YMDB00670geranyl diphosphate
763-10-0
[({[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H20O7P2
314.2091
Thumb
YMDB00707(R)-Mevalonic acid
150-97-0
3,5-dihydroxy-3-methylpentanoic acidC6H12O4
148.1571
Thumb
YMDB007083-Hydroxy-3-methylglutaryl-CoA
1553-55-5
5-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-3-hydroxy-3-methyl-5-oxopentanoic acidC27H44N7O20P3S
911.659
Thumb
YMDB00832all-trans-nonaprenyl diphosphate{[hydroxy({[(2Z,6Z,10Z,14Z,18Z,22Z,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC45H76O7P2
791.0283
Thumb
YMDB00839all-trans-Hexaprenyl diphosphate[({[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidC30H52O7P2
586.6772
Thumb
YMDB00872(S)-3-hydroxy-3-methylglutaryl-CoA
1553-55-5
(3S)-5-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido}ethyl)sulfanyl]-3-hydroxy-3-methyl-5-oxopentanoic acidC27H44N7O20P3S
911.659
Thumb
YMDB00890water
7732-18-5
waterH2O
18.0153
Thumb
YMDB00907phosphate
14265-44-2
phosphoric acidO4P
94.9714
Thumb
YMDB00912Carbon dioxide
124-38-9
methanedioneCO2
44.0095
Thumb
YMDB00914ADP
58-64-0
[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acidC10H15N5O10P2
427.2011
Thumb
YMDB00927Dolichyl diphosphate
37247-98-6
{[hydroxy({[(6E,10E,14E,18E,22Z,26E,30E,34E,38E,42E,46E,50E,54E,58Z,62E,66E,70E,74E)-3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63,67,71,75,79-icosamethyloctaconta-6,10,14,18,22,26,30,34,38,42,46,50,54,58,62,66,70,74,78-nonadecaen-1-yl]oxy})phosphoryl]oxy}phosphonic acidC100H166O7P2
1542.3314
Thumb
YMDB01039(R)-Mevalonate
150-97-0
C6H11O4
147.1491
Thumb
YMDB01053pyruvate
127-17-3
C3H3O3
87.0541
Thumb
YMDB01520Magnesium
7439-95-4
magnesium(2+) ionMg
24.305
Thumb
YMDB16322di-trans, poly-cis-polyprenyl diphosphate (C80)[(3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63-hexadecamethyltetrahexaconta-2,6,10,14,18,22,26,30,34,38,42,46,50,54,58,62-hexadecaen-1-yl phosphonato)oxy]phosphonateC80H129O7P2
1264.854
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P41338ERG10
YPL028W
Acetyl-CoA acetyltransferaseEnzyme
P12683HMG1
YML075C
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1Enzyme
P12684HMG2
YLR450W
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2Enzyme
P54839ERG13
YML126C
Hydroxymethylglutaryl-CoA synthaseEnzyme
P07277ERG12
YMR208W
Mevalonate kinaseEnzyme
P08524ERG20
YJL167W
Farnesyl pyrophosphate synthaseEnzyme
Q12051BTS1
YPL069C
Geranylgeranyl pyrophosphate synthaseEnzyme
P15496IDI1
YPL117C
Isopentenyl-diphosphate Delta-isomeraseEnzyme
P24521ERG8
YMR220W
Phosphomevalonate kinaseEnzyme
P32377MVD1
YNR043W
Diphosphomevalonate decarboxylaseEnzyme
Q12063NUS1
YDL193W
Probable undecaprenyl pyrophosphate synthaseEnzyme
P18900COQ1
YBR003W
Hexaprenyl pyrophosphate synthase, mitochondrialEnzyme
Q03175SRT1
YMR101C
Putative dehydrodolichyl diphosphate synthaseEnzyme
P35196RER2
YBR002C
Dehydrodolichyl diphosphate synthaseEnzyme