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Cardiolipin Biosynthesis CL(10:0/10:0/14:0/26:1(11Z))

SourceIDPathway
PathWhizPW003509 ThumbThumb?image type=greyscaleThumb?image type=simple

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00045Coenzyme A
85-61-0
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acidC21H36N7O16P3S
767.534
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YMDB00073Glycerol 3-phosphate
17989-41-2
[(2R)-2,3-dihydroxypropoxy]phosphonic acidC3H9O6P
172.0737
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YMDB00219Pyrophosphate
14000-31-8
(phosphonooxy)phosphonic acidH4O7P2
177.9751
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YMDB00259LPA(16:0/0:0)[3-(hexadecanoyloxy)-2-hydroxypropoxy]phosphonic acidC19H39O7P
410.4825
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YMDB00279Cytidine triphosphate
65-47-4
({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC9H16N3O14P3
483.1563
Thumb
YMDB00301Palmityl-CoA
1763-10-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-[({[({3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943
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YMDB00322Dihydroxyacetone phosphate
57-04-5
(3-hydroxy-2-oxopropoxy)phosphonic acidC3H7O6P
170.0578
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YMDB00406Cytidine monophosphate
63-37-6
{[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acidC9H14N3O8P
323.1965
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YMDB00426NADPH
53-57-6
{[(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-[({[({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC21H30N7O17P3
745.4209
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YMDB00427NADP
53-59-8
1-[(2R,3R,4S,5R)-5-[({[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-yliumC21H29N7O17P3
744.4129
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YMDB00469hexadec-2-enoyl-CoA
4460-95-1
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadec-2-enoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H64N7O17P3S
1003.927
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YMDB00527palmitoyl-CoA
1763-10-6
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(hexadecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acidC37H66N7O17P3S
1005.943
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YMDB00862hydron
12408-02-5
hydronH
1.00794
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YMDB00890water
7732-18-5
waterH2O
18.0153
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YMDB00907phosphate
14265-44-2
phosphoric acidO4P
94.9714
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YMDB01162PA(16:0/16:1(9Z))[(2R)-2-[(9Z)-hexadec-9-enoyloxy]-3-(hexadecanoyloxy)propoxy]phosphonic acidThumb
YMDB02333CL(10:0/10:0/14:0/26:1(11Z))[(2S)-3-({[(2R)-2,3-bis(decanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy][(2R)-2-[(12Z)-hexacos-12-enoyloxy]-3-(tetradecanoyloxy)propoxy]phosphinic acidC69H132O17P2
1295.746
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YMDB114251-MLCL(0:0/10:0/10:0/14:0)[(2R)-3-(decanoyloxy)-2-(tetradecanoyloxy)propoxy][(2S)-3-({[(2R)-2-(decanoyloxy)-3-hydroxypropoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphinic acidC43H84O16P2
919.077
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YMDB117472-MLCL(10:0/10:0/14:0/0:0)[(2R)-2,3-bis(decanoyloxy)propoxy][(2R)-2-hydroxy-3-({hydroxy[(2R)-2-hydroxy-3-(tetradecanoyloxy)propoxy]phosphoryl}oxy)propoxy]phosphinic acidC43H84O16P2
919.077
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YMDB12067CDP-DG(10:0/10:0){[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-2,3-bis(decanoyloxy)propoxy](hydroxy)phosphoryl}oxy)phosphinic acidC32H57N3O15P2
785.762
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YMDB12153CDP-DG(14:0/26:1(11Z)){[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-2-[(12Z)-hexacos-12-enoyloxy]-3-(tetradecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)phosphinic acidC52H95N3O15P2
1064.286
Thumb
YMDB13412PA(10:0/10:0)[(2R)-2,3-bis(decanoyloxy)propoxy]phosphonic acidC23H45O8P
480.579
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YMDB16273Glycerone phosphatedilithium(1+) ion 1-hydroxy-3-(phosphonatooxy)propan-2-oneC3H5Li2O6P
181.924
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YMDB16289PG(10:0/10:0)[(2R)-2,3-bis(decanoyloxy)propoxy][(2S)-2,3-dihydroxypropoxy]phosphinic acidC26H51O10P
554.658
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YMDB16290PGP(10:0/10:0)[(2S)-3-({[(2R)-2,3-bis(decanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphonic acidC26H52O13P2
634.637
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Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P33333SLC1
YDL052C
Probable 1-acyl-sn-glycerol-3-phosphate acyltransferaseEnzyme
P32784GPT1
YBL011W
Glycerol-3-phosphate O-acyltransferase 1Enzyme
P36148GPT2
YKR067W
Glycerol-3-phosphate O-acyltransferase 2Enzyme
Q08548ALE1
YOR175C
Lysophospholipid acyltransferaseEnzyme
P25578PGS1
YCL004W
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseEnzyme
P38221CDS1
YBR029C
Phosphatidate cytidylyltransferaseEnzyme
Q07560CRD1
YDL142C
Cardiolipin synthaseEnzyme
Q12043TGL5
YOR081C
Lipase 5Enzyme
P36165TGL4
YKR089C
Lipase 4Enzyme
P38812GEP4
YHR100C
Phosphatidylglycerophosphatase GEP4, mitochondrialEnzyme
N1NWI7
Taz1p
N1P9W4
Cld1p
O60200MDM35
Mitochondrial distribution and morphology protein 35TransporterNot Available
P18409MDM10
Mitochondrial distribution and morphology protein 10Not Available
P41800MMM1
Maintenance of mitochondrial morphology protein 1Not Available
P53083MDM34
Mitochondrial distribution and morphology protein 34TransporterNot Available
P53230TAM41
Phosphatidate cytidylyltransferase, mitochondrialEnzyme
Q05776UPS1
Protein UPS1, mitochondrialTransporterNot Available
Q06508LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1Enzyme
Q92328MDM12
Mitochondrial distribution and morphology protein 12Not Available