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Folate biosynthesis

SourceIDPathway
KEGG00790 Map00790

Pathway Metabolites

YMDB ID Name
CAS Number
IUPAC Name Formula
Weight
Structure
YMDB00079Dihydrofolic acid
4033-27-6
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H21N7O6
443.4133
Thumb
YMDB00139Tetrahydrofolic acid
135-16-0
2-{[4-({[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acidC19H23N7O6
445.4292
Thumb
YMDB00148Chorismate
55508-12-8
(3R,4R)-3-[(1-carboxyeth-1-en-1-yl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acidC10H10O6
226.1828
Thumb
YMDB001492-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol
3672-03-5
2-amino-6-(hydroxymethyl)-3,4,7,8-tetrahydropteridin-4-oneC7H9N5O2
195.1787
Thumb
YMDB002937,8-Dihydropteroic acid
2134-76-1
4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoic acidC14H14N6O3
314.2994
Thumb
YMDB003144-amino-4-deoxychorismic acid(3R,4R)-4-amino-3-[(1-carboxyeth-1-en-1-yl)oxy]cyclohexa-1,5-diene-1-carboxylic acidC10H11NO5
225.198
Thumb
YMDB00343Glycolaldehyde
141-46-8
2-hydroxyacetaldehydeC2H4O2
60.052
Thumb
YMDB00430(2-Amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate
3545-84-4
({[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methoxy](hydroxy)phosphoryl}oxy)phosphonic acidC7H11N5O8P2
355.1385
Thumb
YMDB004835,6,7,8-Tetrahydrofolic acid
135-16-0
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acidC19H23N7O6
445.4292
Thumb
YMDB004934-Aminobenzoic acid
150-13-0
4-aminobenzoic acidC7H7NO2
137.136
Thumb
YMDB00558GTP
86-01-1
({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acidC10H16N5O14P3
523.1804
Thumb
YMDB005787,8-dihydroneopterin 3'-triphosphate
20574-65-6
{[({[(2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}phosphonic acidC9H16N5O13P3
495.1703
Thumb
YMDB005797,8-Dihydroneopterin
1218-98-0
2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-3,4,7,8-tetrahydropteridin-4-oneC9H13N5O4
255.2306
Thumb
YMDB006677,8-dihydropteroateC14H14N6O3
314.2994
Thumb
YMDB006687,8-dihydroneopterin 3'-phosphate[(2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropoxy]phosphonic acidC9H14N5O7P
335.2105
Thumb
YMDB007735,6,7,8-tetrahydrofolyl-L-glutamic acid(2S)-2-[(4S)-4-[(4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-carboxybutanamido]pentanedioic acidC24H30N8O9
574.5432
Thumb
YMDB010574-amino-4-deoxychorismate(2-)C15H23N5O14P2
559.3157
Thumb
YMDB010874-Aminobenzoate
150-13-0
C7H6NO2
136.128
Thumb

Pathway Proteins

Uniprot ID Gene Name
Locus
Name Type Metabolites
P37254ABZ1
YNR033W
Aminodeoxychorismate synthaseEnzyme
P07807DFR1
YOR236W
Dihydrofolate reductaseEnzyme
Q12676FOL3
YMR113W
Folylpolyglutamate synthase 1Enzyme
P11491PHO8
YDR481C
Repressible alkaline phosphataseEnzyme
P36001RMA1
YKL132C
Probable folylpolyglutamate synthaseEnzyme
P51601FOL2
YGR267C
GTP cyclohydrolase 1Enzyme
Q08645MET7
YOR241W
Folylpolyglutamate synthaseEnzyme
P53848FOL1
YNL256W
Folic acid synthesis protein FOL1Enzyme
Q03266ABZ2
YMR289W
Aminodeoxychorismate lyaseEnzyme