Alpha-1,2-mannosyltransferase ALG9 (P53868)

Identification
NameAlpha-1,2-mannosyltransferase ALG9
Synonyms
  • Asparagine-linked glycosylation protein 9
  • Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
  • Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Gene NameALG9
Enzyme ClassNot Available
Biological Properties
General Functionprotein glycosylation
Specific FunctionCatalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
Cellular LocationNot Available
SMPDB Pathways
N-Glycan biosynthesisPW002501 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
N-Glycan biosynthesisec00510 Map00510
SMPDB Reactions
(Mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolichol + dolichyl β-D-mannosyl phosphate → (Mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolichol + Dolichol phosphate + hydron
(Mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolichol + dolichyl β-D-mannosyl phosphate → (Mannosyl)9-(N-acetylglucosaminyl)2-diphosphodolichol + Dolichol phosphate + hydron
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00862hydronShow
YMDB00864Dolichol phosphateShow
YMDB16228(Mannosyl)6-(N-acetylglucosaminyl)2-diphosphodolicholShow
YMDB16229(Mannosyl)7-(N-acetylglucosaminyl)2-diphosphodolicholShow
YMDB16230(Mannosyl)8-(N-acetylglucosaminyl)2-diphosphodolicholShow
YMDB16337dolichyl β-D-mannosyl phosphateShow
GO Classification
Function
integral component of membrane
endoplasmic reticulum membrane
endoplasmic reticulum
dolichol-linked oligosaccharide biosynthetic process
protein glycosylation
dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
glycolipid mannosyltransferase activity
mannosyltransferase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1668 bp ATGAATTGCAAGGCGGTAACCATTAGTTTATTACTGTTGTTATTTTTAACAAGAGTATAT ATTCAGCCGACATTCTCGTTAATTTCAGATTGCGATGAAACTTTTAATTATTGGGAACCA TTAAATTTATTGGTACGTGGATTTGGTAAACAAACCTGGGAATATTCACCCGAGTATTCT ATTAGATCATGGGCTTTCTTATTACCTTTTTACTGTATTCTTTATCCAGTAAACAAATTT ACTGACCTAGAAAGTCATTGGAACTTTTTCATCACAAGAGCATGCTTAGGCTTTTTTAGT TTTATCATGGAATTTAAACTACATCGTGAAATTGCAGGCAGCTTGGCATTGCAAATCGCA AATATTTGGATTATTTTCCAATTGTTTAATCCGGGCTGGTTCCATGCATCTGTGGAATTA TTGCCTTCTGCCGTTGCCATGTTGTTGTATGTAGGTGCCACCAGACACTCTCTACGCTAT CTGTCCACTGGGTCTACTTCTAACTTTACGAAAAGTTTAGCGTACAATTTCCTGGCTAGT ATACTAGGCTGGCCATTTGTTTTAATTTTAAGCTTGCCATTATGTTTACATTACCTTTTC AACCATAGAATTATTTCTACCATCAGAACCGCATTCGACTGCTGTTTGATATTTTCATTG ACTGCATTTGCTGTGATTGTCACTGACAGTATATTTTACGGGAAGCTTGCTCCTGTATCA TGGAACATCTTATTTTACAATGTCATTAATGCAAGTGAGGAATCTGGCCCAAATATTTTC GGGGTTGAGCCATGGTACTACTATCCACTAAATTTGTTACTGAATTTCCCACTGCCTGTG CTAGTTTTAGCTATTTTGGGAATTTTCCATTTGAGATTATGGCCATTATGGGCATCATTA TTCACATGGATTGCCGTTTTCACTCAACAACCTCACAAAGAGGAAAGATTTCTCTATCCA ATTTACGGGTTAATAACTTTGAGTGCAAGTATCGCCTTTTACAAAGTGTTGAATCTATTC AATAGAAAGCCGATTCTTAAAAAAGGTATAAAGTTGTCAGTTTTATTAATTGTTGCAGGC CAGGCAATGTCACGGATAGTGGCTTTGGTGAACAATTACACAGCTCCTATAGCCGTCTAC GAGCAATTTTCTTCACTAAATCAAGGTGGTGTGAAGGCACCGGTAGTGAATGTATGTACG GGACGTGAATGGTATCACTTCCCAAGTTCTTTCCTGCTGCCAGATAATCATAGGCTAAAA TTTGTTAAATCTGGATTTGATGGTCTTCTTCCAGGTGATTTTCCAGAGAGTGGTTCTATT TTCAAAAAGATTAGAACTTTACCTAAGGGAATGAATAACAAGAATATATATGATACCGGT AAAGAGTGGCCGATCACTAGATGTGATTATTTTATTGACATCGTCGCCCCAATAAATTTA ACAAAAGACGTTTTCAACCCTCTACATCTGATGGATAACTGGAATAAGCTGGCATGTGCT GCATTCATCGACGGTGAAAATTCTAAGATTTTGGGTAGAGCATTTTACGTACCGGAGCCA ATCAACCGAATCATGCAAATAGTTTTACCAAAACAATGGAATCAAGTGTACGGTGTTCGT TACATTGATTACTGTTTGTTTGAAAAACCAACTGAGACTACTAATTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues555
Protein Molecular Weight63776.03
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane Regions
  • 8-28
  • 63-83
  • 87-107
  • 114-134
  • 177-197
  • 214-234
  • 269-289
  • 317-337
  • 350-370
Protein Sequence>Alpha-1,2-mannosyltransferase ALG9 MNCKAVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYS IRSWAFLLPFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIA NIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLAS ILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVS WNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWPLWASL FTWIAVFTQQPHKEERFLYPIYGLITLSASIAFYKVLNLFNRKPILKKGIKLSVLLIVAG QAMSRIVALVNNYTAPIAVYEQFSSLNQGGVKAPVVNVCTGREWYHFPSSFLLPDNHRLK FVKSGFDGLLPGDFPESGSIFKKIRTLPKGMNNKNIYDTGKEWPITRCDYFIDIVAPINL TKDVFNPLHLMDNWNKLACAAFIDGENSKILGRAFYVPEPINRIMQIVLPKQWNQVYGVR YIDYCLFEKPTETTN
References
External Links
ResourceLink
Saccharomyces Genome Database ALG9
Uniprot IDP53868
Uniprot NameALG9
General ReferenceNot Available