Probable mannosyltransferase YUR1 (P26725)

Identification
NameProbable mannosyltransferase YUR1
SynonymsNot Available
Gene NameYUR1
Enzyme Class
Biological Properties
General FunctionInvolved in mannosyltransferase activity
Specific FunctionPossible glycosyltransferase involved in N-linked glycosylation
Cellular LocationGolgi apparatus membrane; Single-pass type II membrane protein
SMPDB Pathways
N-Glycan biosynthesisPW002501 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
N-Glycan biosynthesisec00510 Map00510
SMPDB ReactionsNot Available
KEGG Reactions
Beta-1,4-D-Mannosylchitobiosyldiphosphodolichol + Guanosine diphosphate mannose → alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol + hydron + Guanosine diphosphate
Metabolites
YMDB IDNameView
YMDB00202Guanosine diphosphate mannoseShow
YMDB00257Guanosine diphosphateShow
YMDB00581alpha-D-mannosyl-beta-D-mannosyldiacetylchitobiosyldiphosphodolicholShow
YMDB00862hydronShow
YMDB00935beta-D-mannosyldiacetylchitobiosyldiphosphodolicholShow
GO Classification
Component
cell part
membrane
Function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
mannosyltransferase activity
alpha-1,2-mannosyltransferase activity
glycolipid 2-alpha-mannosyltransferase activity
Process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process
protein amino acid glycosylation
Gene Properties
Chromosome Locationchromosome 10
LocusYJL139C
Gene Sequence>1287 bp ATGGCAAAAGGAGGCTCGCTATACATCGTTGGCATATTCTTACCAATATGGACCTTTATG ATCTATATTTTTGGCAAAGAGTTATTCCTCATACGAAAATACCAAAAGATTGACAGTACG TATACTGCTCTTTCCCAAAGAGTAAAAGAACAATATGATACAAGTCGAAGAAGAAACTAT TTTCCTAAAGTAAAACTTTCCCGCAATAGCTACGACGACTACACTTTAAATTATACCAGA CAGAATGATTCTGATTCTTTTCACCTACGAGAAAATGCAACAATTTTAATGCTGGTGAGA AATTCAGAATTAGAAGGGGCATTGGATTCAATGAGATCATTAGAGGACAGATTTAACAAC AAGTATCATTATGATTGGACTTTTCTAAATGACGTTCCTTTCGATCAAGACTTCATTGAA GCTACAACATCAATGGCGAGTGGGAAGACCCAATATGCTTTAATACCACCAGAAGATTGG AATCGGCCGCAATGGATTAACGATACACTTTTTGAAGAAAGACTTCGAGTCATGGAGGAT GAGGGTGTTTTATATGGGGGATCCAAGTCATATAGAAATATGTGTCGGTTTAATTCTGGT TTTTTTTTCCGGCAGTCAATACTGGACAACTATGATTACTACTTTAGGGTGGAACCCAAT GTCAAGTATTATTGCGATTTCCCATATGACCCGTTCAGAGTTATGAGATTGAAGGGCAAA AAATACGGATTTGTCATATCATTATATGAATATGAAGAAACCATACCAACCTTATGGGAC GCGGTAGAGGAGTATTTAGTGGCCAGCGAAGAGACCATTTTACGTAAAGAGGACAGTGCC TATGCATTTTTGACCGATTCAGGGCTAGTTGGTAAGCATTATCCCGTTGTTGAAGCAAAC TCTGACTACAATTTGTGCCATTTTTGGTCGAATTTTGAGATTGGCGACTTGAATTTCTTC AGAAGTGACGAATATAAGCATTTTTTTGAAACTTTAGATGCCAAGGGCGGATTTTACTAC GAAAGGTGGGGTGACGCACCTGTACATTCAATTGGTGTCTCCCTACTGCTGAGACCTGAC GAAATCATTCATTTTGACGAACTTGGCTATTTTCACTCACCGTTTGGCACCTGTCCAGCA TCTTACGCTGTTAGGCTCGATCAGAGGTGTAGATGCAAAAGCGATGATGAAAGTGTCATA GATATAACCCCACATAGTTGTTTGATGAGATGGTGGAAAAACGGTAGCGGCAAATATTTC TTAAAAGAAGAGCAAGACGAGATTTAA
Protein Properties
Pfam Domain Function
Protein Residues428
Protein Molecular Weight50835.60156
Protein Theoretical pI4.92
Signalling Regions
  • None
Transmembrane Regions
  • 4-24
Protein Sequence>Probable mannosyltransferase YUR1 MAKGGSLYIVGIFLPIWTFMIYIFGKELFLIRKYQKIDSTYTALSQRVKEQYDTSRRRNY FPKVKLSRNSYDDYTLNYTRQNDSDSFHLRENATILMLVRNSELEGALDSMRSLEDRFNN KYHYDWTFLNDVPFDQDFIEATTSMASGKTQYALIPPEDWNRPQWINDTLFEERLRVMED EGVLYGGSKSYRNMCRFNSGFFFRQSILDNYDYYFRVEPNVKYYCDFPYDPFRVMRLKGK KYGFVISLYEYEETIPTLWDAVEEYLVASEETILRKEDSAYAFLTDSGLVGKHYPVVEAN SDYNLCHFWSNFEIGDLNFFRSDEYKHFFETLDAKGGFYYERWGDAPVHSIGVSLLLRPD EIIHFDELGYFHSPFGTCPASYAVRLDQRCRCKSDDESVIDITPHSCLMRWWKNGSGKYF LKEEQDEI
References
External Links
ResourceLink
Saccharomyces Genome Database YUR1
Uniprot IDP26725
Uniprot NameYUR1_YEAST
GenBank Gene IDX58099
Genebank Protein ID4833
General Reference
  • Foreman, P. K., Davis, R. W., Sachs, A. B. (1991). "The Saccharomyces cerevisiae RPB4 gene is tightly linked to the TIF2 gene." Nucleic Acids Res 19:2781.2041753
  • Katsoulou, C., Tzermia, M., Tavernarakis, N., Alexandraki, D. (1996). "Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI." Yeast 12:787-797.8813765
  • Galibert, F., Alexandraki, D., Baur, A., Boles, E., Chalwatzis, N., Chuat, J. C., Coster, F., Cziepluch, C., De Haan, M., Domdey, H., Durand, P., Entian, K. D., Gatius, M., Goffeau, A., Grivell, L. A., Hennemann, A., Herbert, C. J., Heumann, K., Hilger, F., Hollenberg, C. P., Huang, M. E., Jacq, C., Jauniaux, J. C., Katsoulou, C., Karpfinger-Hartl, L., et, a. l. .. (1996). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J 15:2031-2049.8641269
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106