Purine-cytosine permease FCY22 (Q12119)

Identification
NamePurine-cytosine permease FCY22
Synonyms
  • PCP FCY22
  • Cytosine/purine transport protein FCY22
  • Fluorocytosine resistance protein 22
Gene NameFCY22
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in nucleobase transmembrane transporter activity
Specific FunctionProbable purine-cytosine permease
Cellular LocationMembrane; Multi-pass membrane protein (Probable)
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00651CytosineShow
YMDB00698GuanineShow
YMDB00862hydronShow
YMDB00887AdenineShow
GO Classification
Component
cell part
membrane
Function
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity
nucleobase transmembrane transporter activity
Process
transmembrane transport
establishment of localization
transport
nucleobase, nucleoside, nucleotide and nucleic acid transport
Gene Properties
Chromosome Locationchromosome 5
LocusYER060W-A
Gene Sequence>1593 bp ATGCCAGAAAAGTTAGCCATGTCAATGGTCGATATAAAAGATGCGGGGAGTGAACTAAGG GACCTCGAATCTGGAGCTCTGGACACAAAATCTTCCGCCGCTGATGTATACTATGAGGGT GTAGAATTGCATAGAACCAACGAATTCATTGATAATAAGCCGTCCTTTTTCAATAGGATT GCAGCTGCTTTAAATGCTGAGACGAAAGGTATTGAACCAGTTACAGAAGATGAAAAAAAT GATGACTCGATACTCAATGCCGCCACTATATGGTTTTCAGCTAATATGGTGATTGTAGCC TATTCCGTAGGTGCCTTGGGTCCTCTAGTATTTGGCCTAAATTTCGGCCAAAGTGTTTTA GTTATCATTTTTTTCAATATTTTGGGTTTGATCCCTGTTGCATTATTCTCACTTTTTGGG GTAGAACTGGGCCTAAGACAGATGATTCTATCGAGATATTTGGCTGGTAACATCACAGCA AGATTTTTCTCTCTTGTTAATGTCATTGCTTGTGTCGGTTGGTGTGTTTTAAATATTTCT GTTTCTGCTCAACTTTTGAATATGGTGAATGAAGGCTCTGGGCACAACTGTCCTATTTGG GCAGGTTGTTTGATTATTGCTGGTGGTACCGTGCTTGTGACTTTTTTTGGTTACAGTGTC GTTCATGCATACGAAAAATGGTCGTGGGTACCCAATTTTGCTGCCTTTTTGGTCATTATT GCCCAACTATCGAGATCAGGAAAATTTAAAGGTGGTGAATGGGTAGGGGGTGCAACTACT GCAGGTGGTGTTCTTTCTTTTGGTTCATCTGTTTTTGGGTCAGCTGCGGGTTGGGCGACT TATGCAGCAGATTACACTGTTTATATGCCAAAGACCACAAGTAAATACAAAATTTTTTTT TCCGTAGTAGCCGGTCTAGCGTTCCCTCTATTTTTCACCATGATTCTTGGTGCTGCTTGC GGTATGGCGGCCCTTAATGACCCAACCTGGAAGTCATATTATGATAAAAACGCCATGGGT GGTGTCATATATGCTATCCTGGTCCCTAACTCTCTAAACGGATTCGGTCAATTCTGCTGT GTTTTGTTGGCTCTTTCAACTGTTGCTAATAATGTCCCTGGAATGTACACTGTCGCTTTA TCCGCTCAAGCTTTGTGGGCACCTTTGGCTAAAATACCAAGAGTAGTCTGGACAATGGCA GGTAATGCTGCCACTTTAGGTATTTCCATCCCTGCTACCTATTACTTTGACGGCTTTATG GAGAATTTTATGGATTCCATTGGTTATTATTTGGCTATTTATATTGCCATTGCATGTTCA GAGCATTTTATTTATAGGCGTTCCTTCAGTGCTTACAATATTGATGATTGGGATAATTGG GAGCATCTACCTATCGGTATCGCAGGTACTGCTGCCTTAATTGCTGGTGCCTTTGGAGTA GCGTTGGGTATGTGCCAAACTTATTGGGTTGGTGAGATCAGTCGTTTGATCGGAGAGTAC GGCGGTGACATTGGGTTCGAGTTAGGCGGAAGTTGGGCGTTCATCATCTATAACATTGTA AGACCTTTAGAACTCAAATATTTCGGTCGATGA
Protein Properties
Pfam Domain Function
Protein Residues530
Protein Molecular Weight57326.69922
Protein Theoretical pI4.84
Signalling Regions
  • None
Transmembrane Regions
  • 96-116
  • 119-139
  • 162-182
  • 197-217
  • 220-240
  • 263-283
  • 298-318
  • 345-365
  • 372-392
  • 396-416
  • 418-438
  • 463-483
Protein Sequence>Purine-cytosine permease FCY22 MPEKLAMSMVDIKDAGSELRDLESGALDTKSSAADVYYEGVELHRTNEFIDNKPSFFNRI AAALNAETKGIEPVTEDEKNDDSILNAATIWFSANMVIVAYSVGALGPLVFGLNFGQSVL VIIFFNILGLIPVALFSLFGVELGLRQMILSRYLAGNITARFFSLVNVIACVGWCVLNIS VSAQLLNMVNEGSGHNCPIWAGCLIIAGGTVLVTFFGYSVVHAYEKWSWVPNFAAFLVII AQLSRSGKFKGGEWVGGATTAGGVLSFGSSVFGSAAGWATYAADYTVYMPKTTSKYKIFF SVVAGLAFPLFFTMILGAACGMAALNDPTWKSYYDKNAMGGVIYAILVPNSLNGFGQFCC VLLALSTVANNVPGMYTVALSAQALWAPLAKIPRVVWTMAGNAATLGISIPATYYFDGFM ENFMDSIGYYLAIYIAIACSEHFIYRRSFSAYNIDDWDNWEHLPIGIAGTAALIAGAFGV ALGMCQTYWVGEISRLIGEYGGDIGFELGGSWAFIIYNIVRPLELKYFGR
References
External Links
ResourceLink
Saccharomyces Genome Database FCY22
Uniprot IDQ12119
Uniprot NameFCY22_YEAST
GenBank Gene IDU18813
Genebank Protein ID1381130
General Reference
  • Dietrich, F. S., Mulligan, J., Hennessy, K., Yelton, M. A., Allen, E., Araujo, R., Aviles, E., Berno, A., Brennan, T., Carpenter, J., Chen, E., Cherry, J. M., Chung, E., Duncan, M., Guzman, E., Hartzell, G., Hunicke-Smith, S., Hyman, R. W., Kayser, A., Komp, C., Lashkari, D., Lew, H., Lin, D., Mosedale, D., Davis, R. W., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Nature 387:78-81.9169868