You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Yeast Metabolome Database.
Identification |
---|
Name | Histidinol-phosphatase |
---|
Synonyms | |
---|
Gene Name | HIS2 |
---|
Enzyme Class | |
---|
Biological Properties |
---|
General Function | Involved in histidinol-phosphatase activity |
---|
Specific Function | L-histidinol phosphate + H(2)O = L-histidinol + phosphate |
---|
Cellular Location | Cytoplasmic |
---|
SMPDB Pathways | |
---|
KEGG Pathways | |
---|
SMPDB Reactions | |
---|
KEGG Reactions | |
---|
Metabolites | YMDB ID | Name | View |
---|
YMDB00123 | L-histidinol phosphate | Show | YMDB00702 | L-histidinol | Show | YMDB00890 | water | Show | YMDB00907 | phosphate | Show |
|
---|
GO Classification | Component |
---|
Not Available | Function |
---|
catalytic activity | hydrolase activity | hydrolase activity, acting on ester bonds | phosphoric ester hydrolase activity | phosphatase activity | histidinol-phosphatase activity | Process |
---|
metabolic process | cellular metabolic process | cellular amino acid and derivative metabolic process | cellular amino acid metabolic process | histidine family amino acid metabolic process | histidine metabolic process | histidine biosynthetic process |
|
---|
Gene Properties |
---|
Chromosome Location | chromosome 6 |
---|
Locus | YFR025C |
---|
Gene Sequence | >1008 bp
ATGCACTCACACCATTCACACTCCGGTGACTATAGTGCCCACGGTACGGACCCTTTGGAT
TCCGTGGTCGATCAAGTGGTCAACCTCAACTTTCACACGTACTGTTTGACAGAGCACATA
CCAAGAATTGAGGCCAAGTTTATATACCCCGAAGAGCAGTCATTGGGCAAGAATCCTGAG
GAAGTCATAACCAAGCTAGAAACATCGTTCAAGAATTTCATGAGTCATGCGCAAGAAATC
AAGACTCGTTATGCTGATAGACCCGATGTGCGGACTAAATTCATTATAGGAATGGAGATC
GAAAGTTGTGACATGGCTCATATCGAATATGCAAAGCGACTCATGAAGGAGAATAATGAT
ATTTTGAAGTTTTGTGTGGGTTCGGTCCATCACGTCAACGGGATCCCTATTGATTTCGAC
CAACAACAATGGTACAATTCATTGCATTCCTTCAATGATAATTTGAAACATTTTCTCCTG
TCTTACTTCCAATCACAGTACGAAATGCTGATCAATATTAAACCGTTGGTCGTGGGTCAC
TTCGACCTTTACAAATTATTTTTGCCCAATGACATGCTAGTAAACCAGAAATCGGGCAAC
TGCAACGAAGAAACCGGAGTTCCTGTAGCTTCACTGGACGTCATCAGTGAATGGCCAGAA
ATATACGATGCAGTTGTAAGAAATTTACAATTTATAGACTCCTATGGCGGCGCAATTGAA
ATCAATACGTCCGCATTAAGAAAGCGCCTCGAGGAGCCGTACCCCAGCAAAACCTTATGT
AATCTGGTCAAGAAGCACTGTGGATCCAGATTTGTTCTAAGTGATGACGCACACGGCGTG
GCGCAAGTGGGTGTGTGCTATGACAAGGTAAAGAAATACATAGTAGACGTGCTACAATTA
GAGTATATTTGCTACCTTGAGGAAAGCCAATCACCAGAGAATCTGTTAACTGTAAAGAGA
TTACCCATTTCGCAATTCGTTAATGATCCCTTTTGGGCCAATATATAA |
---|
Protein Properties |
---|
Pfam Domain Function | |
---|
Protein Residues | 335 |
---|
Protein Molecular Weight | 38581.5 |
---|
Protein Theoretical pI | 5.81 |
---|
Signalling Regions | |
---|
Transmembrane Regions | |
---|
Protein Sequence | >Histidinol-phosphatase
MHSHHSHSGDYSAHGTDPLDSVVDQVVNLNFHTYCLTEHIPRIEAKFIYPEEQSLGKNPE
EVITKLETSFKNFMSHAQEIKTRYADRPDVRTKFIIGMEIESCDMAHIEYAKRLMKENND
ILKFCVGSVHHVNGIPIDFDQQQWYNSLHSFNDNLKHFLLSYFQSQYEMLINIKPLVVGH
FDLYKLFLPNDMLVNQKSGNCNEETGVPVASLDVISEWPEIYDAVVRNLQFIDSYGGAIE
INTSALRKRLEEPYPSKTLCNLVKKHCGSRFVLSDDAHGVAQVGVCYDKVKKYIVDVLQL
EYICYLEESQSPENLLTVKRLPISQFVNDPFWANI |
---|
References |
---|
External Links | |
---|
General Reference | - Malone, R. E., Kim, S., Bullard, S. A., Lundquist, S., Hutchings-Crow, L., Cramton, S., Lutfiyya, L., Lee, J. (1994). "Analysis of a recombination hotspot for gene conversion occurring at the HIS2 gene of Saccharomyces cerevisiae." Genetics 137:5-18.8056323
- Eki, T., Naitou, M., Hagiwara, H., Abe, M., Ozawa, M., Sasanuma, S., Sasanuma, M., Tsuchiya, Y., Shibata, T., Watanabe, K., et, a. l. .. (1996). "Fifteen open reading frames in a 30.8 kb region of the right arm of chromosome VI from Saccharomyces cerevisiae." Yeast 12:177-190.8686381
- Murakami, Y., Naitou, M., Hagiwara, H., Shibata, T., Ozawa, M., Sasanuma, S., Sasanuma, M., Tsuchiya, Y., Soeda, E., Yokoyama, K., et, a. l. .. (1995). "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Nat Genet 10:261-268.7670463
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
|
---|