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Identification |
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Name | Putative formate dehydrogenase 2 |
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Synonyms | - NAD-dependent formate dehydrogenase 2
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Gene Name | FDH2 |
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Enzyme Class | |
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Biological Properties |
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General Function | Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
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Specific Function | Formate + NAD(+) = CO(2) + NADH |
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Cellular Location | Cytoplasm |
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SMPDB Pathways | Not Available |
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KEGG Pathways | Glyoxylate and dicarboxylate metabolism | ec00630 | | Methane metabolism | ec00680 | |
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SMPDB Reactions | Not Available |
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KEGG Reactions | Not Available |
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Metabolites | YMDB ID | Name | View |
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YMDB00110 | NAD | Show | YMDB00143 | NADH | Show | YMDB00385 | Formic acid | Show | YMDB00412 | NAD(+) | Show | YMDB00912 | Carbon dioxide | Show |
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GO Classification | Component |
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Not Available | Function |
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catalytic activity | binding | oxidoreductase activity | cofactor binding | oxidoreductase activity, acting on CH-OH group of donors | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Process |
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metabolic process |
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Gene Properties |
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Chromosome Location | chromosome 16 |
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Locus | YPL275W |
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Gene Sequence | >711 bp
ATGGTGGTCATCAATAAGCAATTAATGGTGAGTGGGATATTGCCGGCGTGGCTAAAAAAT
GAGTATGATCTGGAAGACAAAATAATTTCAACGGTAGGTGCCGGTAGAATTGGATATAGG
GTTCTGGAAAGATTGGTCGCATTTAATCCGAAGAAGTTACTGTACTACGACTACCAGGAA
CTACCTGCGGAAGCAATCAATAGATTGAACGAGGCCAGCAAGCTTTTCAATGGCAGAGGT
GATATTGTTCAGAGAGTAGAGAAATTGGAGGATATGGTTGCTCAGTCAGATGTTGTTACC
ATCAACTGTCCATTGCACAAGGACTCAAGGGGTTTATTCAATAAAAAGCTTATTTCCCAC
ATGAAAGATGGTGCATACTTGGTGAATACCGCTAGAGGTGCTATTTGTGTCGCAGAAGAT
GTTGCCGAGGCAGTCAAGTCTGGTAAATTGGCTGGCTATGGTGGTGATGTCTGGGATAAG
CAACCAGCACCAAAAGACCATCCCTGGAGGACTATGGACAATAAGGACCACGTGGGAAAC
GCAATGACTGTTCATATCAGTGGCACATCTCTGCATGCTCAAAAGAGGTACGCTCAGGGA
GTAAAGAACATCCTAAATAGTTACTTTTCCAAAAAGTTTGATTACCGTCCACAGGATATT
ATTGTGCAGAATGGTTCTTATGCCACCAGAGCTTATGGACAGAAGAAATAA |
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Protein Properties |
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Pfam Domain Function | |
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Protein Residues | 236 |
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Protein Molecular Weight | 26487.19922 |
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Protein Theoretical pI | 9.71 |
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Signalling Regions | |
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Transmembrane Regions | |
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Protein Sequence | >Putative formate dehydrogenase 2
MVVINKQLMVSGILPAWLKNEYDLEDKIISTVGAGRIGYRVLERLVAFNPKKLLYYDYQE
LPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVAQSDVVTINCPLHKDSRGLFNKKLISH
MKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDVWDKQPAPKDHPWRTMDNKDHVGN
AMTVHISGTSLHAQKRYAQGVKNILNSYFSKKFDYRPQDIIVQNGSYATRAYGQKK |
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References |
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External Links | |
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General Reference | - Bussey, H., Storms, R. K., Ahmed, A., Albermann, K., Allen, E., Ansorge, W., Araujo, R., Aparicio, A., Barrell, B., Badcock, K., Benes, V., Botstein, D., Bowman, S., Bruckner, M., Carpenter, J., Cherry, J. M., Chung, E., Churcher, C., Coster, F., Davis, K., Davis, R. W., Dietrich, F. S., Delius, H., DiPaolo, T., Hani, J., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Nature 387:103-105.9169875
- Overkamp, K. M., Kotter, P., van der Hoek, R., Schoondermark-Stolk, S., Luttik, M. A., van Dijken, J. P., Pronk, J. T. (2002). "Functional analysis of structural genes for NAD(+)-dependent formate dehydrogenase in Saccharomyces cerevisiae." Yeast 19:509-520.11921099
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