| Identification |
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| Name | Putative prolyl-tRNA synthetase YHR020W |
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| Synonyms | - Proline--tRNA ligase
- ProRS
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| Gene Name | Not Available |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in nucleotide binding |
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| Specific Function | ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro) |
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| Cellular Location | Not Available |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00097 | Adenosine monophosphate | Show | | YMDB00109 | Adenosine triphosphate | Show | | YMDB00219 | Pyrophosphate | Show | | YMDB00378 | L-Proline | Show | | YMDB00862 | hydron | Show |
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| GO Classification | | Component |
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| cell part | | intracellular part | | cytoplasm | | Function |
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| ligase activity, forming aminoacyl-tRNA and related compounds | | catalytic activity | | aminoacyl-tRNA ligase activity | | nucleotide binding | | ligase activity | | binding | | nucleoside binding | | purine nucleoside binding | | adenyl nucleotide binding | | proline-tRNA ligase activity | | adenyl ribonucleotide binding | | ATP binding | | ligase activity, forming carbon-oxygen bonds | | Process |
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| metabolic process | | macromolecule metabolic process | | cellular macromolecule metabolic process | | RNA metabolic process | | ncRNA metabolic process | | biosynthetic process | | tRNA metabolic process | | tRNA aminoacylation | | tRNA aminoacylation for protein translation | | macromolecule biosynthetic process | | cellular macromolecule biosynthetic process | | translation | | prolyl-tRNA aminoacylation |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | YHR020W |
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| Gene Sequence | >2067 bp
ATGCCTGTTTCGGAAGCGTTTGCCAAGTTGTGTGTGAATGAGAAGCCTCCTGCTGAATCT
GCCGTTGCGGTGAAGTCTTTGGTCTTCAAACCAAAGACTCCAAAGTCCGCCACCCCTGTT
CCTATCGTTGTGGTGGCTTTGCAATCTACTACTACTCCTTCTGCGTTGATTGCCAACGCT
ACGTCCAGTAAGGATCCAAGATTGGCTCGCGATGATTTGGTCAAGCAAGCGTTCCAATCT
GAATCCGCTAGAGCTTTTATCTTGGGGGATTTGGCTAACGCCACGTCCAATTTTCACTTG
CTAATTGATCACGAGTTGGGTACTGTTGACGGTGACACTATCTTGCAGTTAAACGACAGT
ACTTATATGAAGAAATCTGACATGATGAAATTTCTAAACAATTTTGAGGATAGTCAAAAA
GTGGTTGATTTCTCCCAAGAGGTGTCTAAGGAAACCGCTACAGAAGGCAAGAAACAACAG
AAAAAGCAGCAACCTTCTAAGGCAGGCACTGCAGCAGCAGCAGCAGCAGCAGCTTTGGAA
GACGCCAAACTTATTGGTATCACCGTAGACAAAGCGTTGGATTTCCCAGGCTGGTACCAA
CAAATCTTGACCAAGGGTGAAATGTTGGACTACTACGATGTTTCTGGCTGTTACATCTTA
AGACCTCCTTCTTATGCGATCTGGGAAAACATTCAGAAATGGTTCGACGACAAGATCAAG
GCCATTGGTGTACAAAATGCCTATTTCCCAATGTTTGTTTCCTCACGTGTGTTGGAAAAG
GAAAAGGACCATGTTGAAGGCTTTGCTCCAGAAGTTGCCTGGGTCACCAGAGCTGGCTCC
TCTGAATTGGAAGAACCAATCGCCATTAGACCAACTTCTGAAACTGTCATGTATCCTTAC
TACGCAAAATGGGTCCAGTCTTACAGAGATTTACCATTGAAACTAAACCAATGGAATTCT
GTGGTTAGATGGGAATTCAAGCATCCTCAGCCCTTTTTAAGAACCAGAGAATTCTTGTGG
CAAGAAGGTCATACTGCTCACTTGACTGCTAAGGATGCCGAAGAGGAGGTTTTGCAAATC
TTAGATTTCTACGCTGGGGTTTACGAAGAGTTATTAGCTGTTCCAGTGGTTAAGGGTAGA
AAGACCGAAAAGGAAAAATTTGCTGGTGGTGACTTCACCACAACTTGTGAAGGCTATATT
CCACAAACCGGTCGTGGTATTCAAGGTGCCACCTCTCACCATTTGGGCCAAAACTTTTCT
AAGATGTTCAATTTGTCTGTGGAGAACCCACTAGGTTCTGATCATCCAAAGATCTTTGCG
TACCAAAATTCATGGGGTTTATCCACTCGTGTCATTGGTGTCATGGTCATGATCCACTCT
GACAACAAGGGTTTGGTTATCCCACCAAGAGTGTCCCAATTCCAATCCGTTGTCATTCCA
GTGGGCATCACAAAGAAGACCTCTGAGGAACAGCGTAAACACATTCATGAAACAGCCAGA
AGTGTGGAATCCCGTTTGAAAAAGGTTGGCATTAGAGCCTTTGGTGACTATAACGATAAT
TACACACCAGGTTGGAAATTTTCCCAATACGAGCTAAAGGGTATTCCAATCCGTATTGAA
TTAGGTCCTAAGGATATTGAAAAAAACCAAGTCGTTGTCGTTCGTAGAAATGACTCCAAG
AAATACGTCGTTTCTTTCGACGAATTGGAAGCCCGTATCCCAGAAATCTTAGAAGAAATG
CAAGGAGATTTGTTCAAAAAAGCCAAGGAGCTATTCGACACCCACAGAGTTATCGTTAAT
GAATGGAGTGGTTTTGTTCCAGCATTGAACAAGAAGAACGTTATCTTAGCACCATGGTGT
GGTGTGATGGAATGTGAAGAAGATATCAAGGAATCTTCTGCAAAGAAAGACGATGGTGAA
GAATTCGAGGAAGATGACAAGGCACCAAGTATGGGTGCCAAATCTTTATGTATCCCATTC
GACCAACCTGTATTGAATGAAGGTCAAAAATGTATCAAGTGTGAACGTATTGCTGTCAAT
TACTGTATGTTCGGTCGTTCTTATTAG |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 688 |
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| Protein Molecular Weight | 77385.70313 |
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| Protein Theoretical pI | 6.35 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >Putative prolyl-tRNA synthetase YHR020W
MPVSEAFAKLCVNEKPPAESAVAVKSLVFKPKTPKSATPVPIVVVALQSTTTPSALIANA
TSSKDPRLARDDLVKQAFQSESARAFILGDLANATSNFHLLIDHELGTVDGDTILQLNDS
TYMKKSDMMKFLNNFEDSQKVVDFSQEVSKETATEGKKQQKKQQPSKAGTAAAAAAAALE
DAKLIGITVDKALDFPGWYQQILTKGEMLDYYDVSGCYILRPPSYAIWENIQKWFDDKIK
AIGVQNAYFPMFVSSRVLEKEKDHVEGFAPEVAWVTRAGSSELEEPIAIRPTSETVMYPY
YAKWVQSYRDLPLKLNQWNSVVRWEFKHPQPFLRTREFLWQEGHTAHLTAKDAEEEVLQI
LDFYAGVYEELLAVPVVKGRKTEKEKFAGGDFTTTCEGYIPQTGRGIQGATSHHLGQNFS
KMFNLSVENPLGSDHPKIFAYQNSWGLSTRVIGVMVMIHSDNKGLVIPPRVSQFQSVVIP
VGITKKTSEEQRKHIHETARSVESRLKKVGIRAFGDYNDNYTPGWKFSQYELKGIPIRIE
LGPKDIEKNQVVVVRRNDSKKYVVSFDELEARIPEILEEMQGDLFKKAKELFDTHRVIVN
EWSGFVPALNKKNVILAPWCGVMECEEDIKESSAKKDDGEEFEEDDKAPSMGAKSLCIPF
DQPVLNEGQKCIKCERIAVNYCMFGRSY |
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| References |
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| External Links | |
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| General Reference | - Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
- Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956
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