Ferulic acid decarboxylase 1 (Q03034)

Identification
NameFerulic acid decarboxylase 1
Synonyms
  • Phenacrylate decarboxylase
Gene NameFDC1
Enzyme ClassNot Available
Biological Properties
General Functionferulate metabolic process
Specific FunctionCatalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites (PubMed:20471595, PubMed:25647642). Not essential for ubiquinone synthesis (PubMed:20471595).
Cellular LocationNot Available
SMPDB Pathways
Beer ReactionsPW002719 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB Reactions
4-Vinylguaiacol + Carbon dioxide ↔ Ferulic acid + hydron
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00862hydronShow
YMDB00912Carbon dioxideShow
YMDB01325Ferulic acidShow
YMDB016244-VinylguaiacolShow
GO Classification
Function
metal ion binding
oxidoreductase activity
cytoplasm
carboxy-lyase activity
FMN binding
cinnamic acid catabolic process
ferulate metabolic process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1512 bp ATGAGGAAGCTAAATCCAGCTTTAGAATTTAGAGACTTTATCCAGGTCTTAAAAGATGAA GATGACTTAATCGAAATTACCGAAGAGATTGATCCAAATCTCGAAGTAGGTGCAATTATG AGGAAGGCCTATGAATCCCACTTACCAGCCCCGTTATTTAAAAATCTCAAAGGTGCTTCG AAGGATCTTTTCAGCATTTTAGGTTGCCCAGCCGGTTTGAGAAGTAAGGAGAAAGGAGAT CATGGTAGAATTGCCCATCATCTGGGGCTCGACCCAAAAACAACTATCAAGGAAATCATA GATTATTTGCTGGAGTGTAAGGAGAAGGAACCTCTCCCCCCAATCACTGTTCCTGTGTCA TCTGCACCTTGTAAAACACATATACTTTCTGAAGAAAAAATACATCTACAAAGCCTGCCA ACACCATATCTACATGTTTCAGACGGTGGCAAGTACTTACAAACGTACGGAATGTGGATT CTTCAAACTCCAGATAAAAAATGGACTAATTGGTCAATTGCTAGAGGTATGGTTGTAGAT GACAAGCATATCACTGGTCTGGTAATTAAACCACAACATATTAGACAAATTGCTGACTCT TGGGCAGCAATTGGAAAAGCAAATGAAATTCCTTTCGCGTTATGTTTTGGCGTTCCCCCA GCAGCTATTTTAGTTAGTTCCATGCCAATTCCTGAAGGTGTTTCTGAATCGGATTATGTT GGCGCAATCTTGGGTGAGTCGGTTCCAGTAGTAAAATGTGAGACCAACGATTTAATGGTT CCTGCAACGAGTGAGATGGTATTTGAGGGTACTTTGTCCTTAACAGATACACATCTGGAA GGCCCATTTGGTGAGATGCATGGATATGTTTTCAAAAGCCAAGGTCATCCTTGTCCATTG TACACTGTCAAGGCTATGAGTTACAGAGACAATGCTATTCTACCTGTTTCGAACCCCGGT CTTTGTACGGATGAGACACATACCTTGATTGGTTCACTAGTGGCTACTGAGGCCAAGGAG CTGGCTATTGAATCTGGCTTGCCAATTCTGGATGCCTTTATGCCTTATGAGGCTCAGGCT CTTTGGCTTATCTTAAAGGTGGATTTGAAAGGGCTGCAAGCATTGAAGACAACGCCTGAA GAATTTTGTAAGAAGGTAGGTGATATTTACTTTAGGACAAAAGTTGGTTTTATAGTCCAT GAAATAATTTTGGTGGCAGATGATATCGACATATTTAACTTCAAAGAAGTCATCTGGGCC TACGTTACAAGACATACACCTGTTGCAGATCAGATGGCTTTTGATGATGTCACTTCTTTT CCTTTGGCTCCCTTTGTTTCGCAGTCATCCAGAAGTAAGACTATGAAAGGTGGAAAGTGC GTTACTAATTGCATATTTAGACAGCAATATGAGCGCAGTTTTGACTACATAACTTGTAAT TTTGAAAAGGGATATCCAAAAGGATTAGTTGACAAAGTAAATGAAAATTGGAAAAGGTAC GGATATAAATAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues503
Protein Molecular Weight56163.39
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Ferulic acid decarboxylase 1 MRKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGAS KDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVS SAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIARGMVVD DKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYV GAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGEMHGYVFKSQGHPCPL YTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQA LWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWA YVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCN FEKGYPKGLVDKVNENWKRYGYK
References
External Links
ResourceLink
Saccharomyces Genome Database FDC1
Uniprot IDQ03034
Uniprot NameFDC1
PDB ID
4S13
General ReferenceNot Available