High-affinity potassium transport protein (P12685)

Identification
NameHigh-affinity potassium transport protein
SynonymsNot Available
Gene NameTRK1
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in cation transmembrane transporter activity
Specific FunctionThis protein is required for high-affinity potassium transport
Cellular LocationMembrane; Multi-pass membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00782potassium atomShow
YMDB00862hydronShow
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
potassium ion transmembrane transporter activity
transporter activity
transmembrane transporter activity
Process
transmembrane transport
establishment of localization
transport
ion transport
cation transport
monovalent inorganic cation transport
potassium ion transport
Gene Properties
Chromosome Locationchromosome 10
LocusYJL129C
Gene Sequence>3708 bp ATGCATTTTAGAAGAACGATGAGTAGAGTGCCCACATTGGCATCTCTTGAAATACGATAT AAAAAATCTTTCGGCCATAAATTTCGTGATTTTATTGCTCTATGTGGTCACTATTTTGCT CCAGTTAAAAAATATATCTTCCCCAGTTTTATCGCGGTTCACTACTTCTACACGATATCC CTGACATTAATAACTTCAATCCTGCTATATCCCATTAAGAATACCAGATACATTGATACA TTGTTTTTAGCAGCGGGCGCAGTTACACAAGGTGGCTTAAATACTGTGGATATCAACAAT CTAAGCTTATACCAACAAATTGTTCTGTATATCGTATGCTGCATATCAACACCAATTGCA GTTCATAGTTGCTTGGCATTTGTACGGCTTTACTGGTTTGAGCGCTACTTCGATGGTATT AGAGACTCTTCTAGACGAAATTTTAAGATGAGAAGAACGAAAACAATCTTAGAAAGGGAA CTAACAGCAAGAACCATGACCAAGAATAGAACAGGTACCCAAAGAACGTCTTATCCTAGG AAACAAGCTAAAACAGATGATTTCCAAGAAAAATTGTTCAGCGGAGAAATGGTTAATAGA GATGAGCAGGACTCAGTTCACAGCGACCAGAATTCTCATGACATTAGTAGGGACAGCAGC AATAATAATACGAATCACAATGGTAGCAGTGGCAGTTTAGATGATTTCGTTAAGGAAGAC GAAACGGATGACAATGGAGAATATCAGGAGAACAACTCCTACTCGACGGTAGGTAGTTCG TCTAACACAGTTGCAGACGAAAGTTTAAATCAGAAGCCCAAGCCAAGCAGTCTTCGGTTT GATGAGCCACACAGCAAACAAAGACCCGCAAGAGTTCCCTCAGAGAAATTTGCAAAAAGA AGGGGTTCAAGAGATATTAGCCCAGCCGATATGTATCGATCCATTATGATGCTACAAGGT AAGCATGAAGCAACTGCTGAAGATGAAGGTCCCCCTTTAGTCATCGGGTCCCCTGCGGAT GGCACAAGATATAAAAGTAATGTCAATAAGCTAAAGAAGGCCACCGGCATAAATGGTAAC AAAATCAAGATTCGAGATAAGGGAAATGAAAGTAACACTGATCAAAATTCCGTGTCAAGT GAAGCAAACAGTACGGCGAGCGTTTCGGACGAAAGCTCGTTACACACAAATTTTGGTAAC AAAGTACCTTCATTAAGAACAAATACTCATAGATCAAATTCGGGCCCGATAGCCATTACT GATAACGCAGAAACAGACAAAAAGCATGGGCCATCAATTCAATTCGATATAACTAAACCT CCTAGAAAAATTTCAAAAAGAGTTTCAACCTTCGATGATTTGAACCCAAAATCTTCCGTT CTTTATCGAAAAAAAGCATCGAAGAAGTACCTCATGAAACATTTTCCTAAAGCGCGGCGA ATACGGCAACAAATTAAGAGAAGGCTTTCTACTGGTTCAATTGAGAAAAACAGCAGTAAC AATGTTTCAGATAGAAAACCTATTACTGATATGGATGATGATGATGATGACGATGACAAC GACGGCGATAACAACGAAGAATACTTTGCTGACAACGAAAGCGGCGATGAAGATGAACGA GTACAGCAGTCTGAACCACATTCTGATTCAGAACTCAAATCGCACCAACAACAGCAAGAA AAACACCAACTGCAGCAGAACCTGCACCGCATGTATAAAACCAAATCATTTGATGATAAT CGTTCAAGAGCAGTTCCTATGGAACGTTCCAGGACCATCGATATGGCAGAGGCTAAGGAT CTAAATGAGCTCGCAAGGACGCCTGATTTTCAAAAAATGGTCTATCAAAATTGGAAAGCC CATCATAGAAAAAAACCGAACTTTAGGAAGAGGGGATGGAATAACAAGATATTTGAACAT GGTCCCTATGCATCTGACAGCGATCGCAATTATCCTGATAATAGTAATACTGGAAACAGT ATTCTTCATTACGCAGAGTCTATTTTACATCATGATGGCTCTCATAAAAATGGAAGCGAA GAAGCCTCTTCCGACTCTAATGAGAATATCTATTCCACGAATGGAGGAAGCGACCACAAT GGTCTTAACAACTATCCTACTTACAACGACGATGAAGAAGGCTATTATGGTTTACATTTC GATACCGATTATGACCTAGATCCTCGTCATGATTTATCTAAAGGCAGTGGTAAAACGTAT CTATCATGGCAACCAACTATTGGACGTAACTCAAACTTCCTTGGATTAACAAGAGCCCAG AAAGATGAATTAGGTGGTGTCGAGTACAGAGCAATCAAACTTTTATGCACCATATTGGTT GTCTACTACGTTGGATGGCATATTGTTGCTTTTGTTATGTTAGTACCTTGGATTATTTTG AAAAAGCATTATAGTGAAGTTGTTAGAGATGATGGTGTTTCACCTACATGGTGGGGATTT TGGACAGCAATGAGTGCATTTAATGATTTAGGTTTGACATTAACTCCAAATTCAATGATG TCGTTTAACAAAGCTGTATACCCATTGATCGTTATGATTTGGTTTATCATTATCGGAAAT ACAGGGTTTCCCATCCTTCTTAGATGCATCATTTGGATAATGTTTAAAATTTCTCCTGAT TTATCACAGATGAGAGAAAGTTTAGGTTTTCTCTTAGACCATCCACGTCGTTGTTTCACC TTGCTATTTCCTAAGGCAGCTACATGGTGGCTACTTTTAACGCTTGCAGGATTGAATATA ACTGATTGGATTTTATTTATTATTCTAGATTTTGGCTCAACAGTTGTGAAATCATTATCG AAAGGCTATAGAGTCCTTGTCGGCCTGTTTCAATCTGTTAGCACAAGAACTGCTGGATTC AGCGTTGTCGATTTAAGTCAACTGCATCCTTCTATCCAAGTCTCCTATATGCTAATGATG TATGTCTCCGTATTACCATTGGCCATCTCTATTCGACGGACAAATGTTTACGAGGAGCAA TCTTTAGGACTATATGGAGATATGGGGGGAGAACCAGAAGATACGGATACTGAAGACGAT GGTAACGATGAAGATGACGACGAGGAAAACGAGAGTCACGAAGGTCAAAGTAGTCAAAGA AGTAGTTCGAACAACAACAACAATAACAACAGGAAAAAGAAAAAGAAAAAGAAAACTGAA AATCCAAATGAAATATCTACAAAATCCTTTATCGGTGCCCATTTAAGGAAACAGCTTTCA TTTGACTTGTGGTTTCTATTTTTAGGGTTATTTATCATTTGCATTTGTGAAGGGGACAAG ATAAAGGACGTACAAGAACCAAACTTTAATATATTTGCAATTCTTTTTGAAATTGTTAGC GCTTACGGTACAGTTGGGCTATCGCTAGGTTATCCGGACACCAACCAATCGTTTTCAAGA CAGTTTACTACATTATCTAAGTTGGTGATCATAGCTATGCTGATCAGAGGCAAGAATAGA GGTCTACCATACTCACTGGATCGTGCAATTATCTTGCCTAGTGATAGACTTGAACATATT GACCACCTTGAGGGCATGAAATTGAAGAGACAGGCTAGAACCAATACAGAAGACCCAATG ACGGAACATTTCAAGAGAAGTTTCACTGATGTGAAACATCGTTGGGGAGCTCTTAAGCGT AAGACCACACATTCCCGAAATCCTAAAAGGAGCAGCACAACGCTCTAA
Protein Properties
Pfam Domain Function
Protein Residues1235
Protein Molecular Weight141072.0
Protein Theoretical pI8.77
Signalling Regions
  • None
Transmembrane Regions
  • 49-70
  • 78-98
  • 107-127
  • 778-800
  • 813-834
  • 838-858
  • 862-882
  • 898-918
  • 923-943
  • 971-991
  • 1078-1098
  • 1111-1131
Protein Sequence>High-affinity potassium transport protein MHFRRTMSRVPTLASLEIRYKKSFGHKFRDFIALCGHYFAPVKKYIFPSFIAVHYFYTIS LTLITSILLYPIKNTRYIDTLFLAAGAVTQGGLNTVDINNLSLYQQIVLYIVCCISTPIA VHSCLAFVRLYWFERYFDGIRDSSRRNFKMRRTKTILERELTARTMTKNRTGTQRTSYPR KQAKTDDFQEKLFSGEMVNRDEQDSVHSDQNSHDISRDSSNNNTNHNGSSGSLDDFVKED ETDDNGEYQENNSYSTVGSSSNTVADESLNQKPKPSSLRFDEPHSKQRPARVPSEKFAKR RGSRDISPADMYRSIMMLQGKHEATAEDEGPPLVIGSPADGTRYKSNVNKLKKATGINGN KIKIRDKGNESNTDQNSVSSEANSTASVSDESSLHTNFGNKVPSLRTNTHRSNSGPIAIT DNAETDKKHGPSIQFDITKPPRKISKRVSTFDDLNPKSSVLYRKKASKKYLMKHFPKARR IRQQIKRRLSTGSIEKNSSNNVSDRKPITDMDDDDDDDDNDGDNNEEYFADNESGDEDER VQQSEPHSDSELKSHQQQQEKHQLQQNLHRMYKTKSFDDNRSRAVPMERSRTIDMAEAKD LNELARTPDFQKMVYQNWKAHHRKKPNFRKRGWNNKIFEHGPYASDSDRNYPDNSNTGNS ILHYAESILHHDGSHKNGSEEASSDSNENIYSTNGGSDHNGLNNYPTYNDDEEGYYGLHF DTDYDLDPRHDLSKGSGKTYLSWQPTIGRNSNFLGLTRAQKDELGGVEYRAIKLLCTILV VYYVGWHIVAFVMLVPWIILKKHYSEVVRDDGVSPTWWGFWTAMSAFNDLGLTLTPNSMM SFNKAVYPLIVMIWFIIIGNTGFPILLRCIIWIMFKISPDLSQMRESLGFLLDHPRRCFT LLFPKAATWWLLLTLAGLNITDWILFIILDFGSTVVKSLSKGYRVLVGLFQSVSTRTAGF SVVDLSQLHPSIQVSYMLMMYVSVLPLAISIRRTNVYEEQSLGLYGDMGGEPEDTDTEDD GNDEDDDEENESHEGQSSQRSSSNNNNNNNRKKKKKKKTENPNEISTKSFIGAHLRKQLS FDLWFLFLGLFIICICEGDKIKDVQEPNFNIFAILFEIVSAYGTVGLSLGYPDTNQSFSR QFTTLSKLVIIAMLIRGKNRGLPYSLDRAIILPSDRLEHIDHLEGMKLKRQARTNTEDPM TEHFKRSFTDVKHRWGALKRKTTHSRNPKRSSTTL
References
External Links
ResourceLink
Saccharomyces Genome Database TRK1
Uniprot IDP12685
Uniprot NameTRK1_YEAST
GenBank Gene IDM21328
Genebank Protein ID171804
General Reference
  • Gaber, R. F., Styles, C. A., Fink, G. R. (1988). "TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cerevisiae." Mol Cell Biol 8:2848-2859.3043197
  • Cziepluch, C., Kordes, E., Pujol, A., Jauniaux, J. C. (1996). "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon." Yeast 12:1471-1474.8948101
  • Galibert, F., Alexandraki, D., Baur, A., Boles, E., Chalwatzis, N., Chuat, J. C., Coster, F., Cziepluch, C., De Haan, M., Domdey, H., Durand, P., Entian, K. D., Gatius, M., Goffeau, A., Grivell, L. A., Hennemann, A., Herbert, C. J., Heumann, K., Hilger, F., Hollenberg, C. P., Huang, M. E., Jacq, C., Jauniaux, J. C., Katsoulou, C., Karpfinger-Hartl, L., et, a. l. .. (1996). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." EMBO J 15:2031-2049.8641269
  • Li, X., Gerber, S. A., Rudner, A. D., Beausoleil, S. A., Haas, W., Villen, J., Elias, J. E., Gygi, S. P. (2007). "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae." J Proteome Res 6:1190-1197.17330950
  • Albuquerque, C. P., Smolka, M. B., Payne, S. H., Bafna, V., Eng, J., Zhou, H. (2008). "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Mol Cell Proteomics 7:1389-1396.18407956