Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit (Q00764)

Identification
NameAlpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit
Synonyms
  • General glucose sensor subunit 1
  • Glycogen metabolism control protein GLC6
  • Trehalose synthase complex catalytic subunit TPS1
  • Trehalose-6-phosphate synthase
  • UDP-glucose-glucosephosphate glucosyltransferase
Gene NameTPS1
Enzyme Class
Biological Properties
General FunctionInvolved in catalytic activity
Specific FunctionSynthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6- phosphate and UDP-glucose in a two step process. Can function independently of the complex
Cellular LocationCytoplasm
SMPDB Pathways
Starch and sucrose metabolismPW002481 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Starch and sucrose metabolismec00500 Map00500
SMPDB Reactions
Uridine diphosphate glucose + alpha-D-glucose 6 phosphate → Uridine 5'-diphosphate + Trehalose 6-phosphate
Trehalose 6-phosphate + water ↔ Trehalose + phosphate
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00008TrehaloseShow
YMDB00137Trehalose 6-phosphateShow
YMDB00212Uridine diphosphate glucoseShow
YMDB00228alpha,alpha-trehalose 6-phosphateShow
YMDB00307Uridine 5'-diphosphateShow
YMDB00415UDP-D-glucoseShow
YMDB00890waterShow
YMDB00907phosphateShow
YMDB00947Glucose 6-phosphateShow
YMDB16263alpha-D-glucose 6 phosphateShow
GO Classification
Component
Not Available
Function
UDP-glycosyltransferase activity
UDP-glucosyltransferase activity
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
Process
trehalose biosynthetic process
metabolic process
primary metabolic process
carbohydrate metabolic process
oligosaccharide metabolic process
disaccharide metabolic process
trehalose metabolic process
Gene Properties
Chromosome Locationchromosome 2
LocusYBR126C
Gene Sequence>1488 bp ATGACTACGGATAACGCTAAGGCGCAACTGACCTCGTCTTCAGGGGGTAACATTATTGTG GTGTCCAACAGGCTTCCCGTGACAATCACTAAAAACAGCAGTACGGGACAGTACGAGTAC GCAATGTCGTCCGGAGGGCTGGTCACGGCGTTGGAAGGGTTGAAGAAGACGTACACTTTC AAGTGGTTCGGATGGCCTGGGCTAGAGATTCCTGACGATGAGAAGGATCAGGTGAGGAAG GACTTGCTGGAAAAGTTTAATGCCGTACCCATCTTCCTGAGCGATGAAATCGCAGACTTA CACTACAACGGGTTCAGTAATTCTATTCTATGGCCGTTATTCCATTACCATCCTGGTGAG ATCAATTTCGACGAGAATGCGTGGTTGGCATACAACGAGGCAAACCAGACGTTCACCAAC GAGATTGCTAAGACTATGAACCATAACGATTTAATCTGGGTGCATGATTACCATTTGATG TTGGTTCCGGAAATGTTGAGAGTCAAGATTCACGAGAAGCAACTGCAAAACGTTAAGGTC GGGTGGTTCCTGCACACACCATTCCCTTCGAGTGAAATTTACAGAATCTTACCTGTCAGA CAAGAGATTTTGAAGGGTGTTTTGAGTTGTGATTTAGTCGGGTTCCACACATACGATTAT GCAAGACATTTCTTGTCTTCCGTGCAAAGAGTGCTTAACGTGAACACATTGCCTAATGGG GTGGAATACCAGGGCAGATTCGTTAACGTAGGGGCCTTCCCTATCGGTATCGACGTGGAC AAGTTCACCGATGGGTTGAAAAAGGAATCCGTACAAAAGAGAATCCAACAATTGAAGGAA ACTTTCAAGGGCTGCAAGATCATAGTTGGTGTCGACAGGCTGGATTACATCAAAGGTGTG CCTCAGAAGTTGCACGCCATGGAAGTGTTTCTGAACGAGCATCCAGAATGGAGGGGCAAG GTTGTTCTGGTACAGGTTGCAGTGCCAAGTCGTGGAGATGTGGAAGAGTACCAATATTTA AGATCTGTGGTCAATGAGTTGGTCGGTAGAATCAACGGTCAGTTCGGTACTGTGGAATTC GTCCCCATCCATTTCATGCACAAGTCTATACCATTTGAAGAGCTGATTTCGTTATATGCT GTGAGCGATGTTTGTTTGGTCTCGTCCACCCGTGATGGTATGAACTTGGTTTCCTACGAA TATATTGCTTGCCAAGAAGAAAAGAAAGGTTCCTTAATCCTGAGTGAGTTCACAGGTGCC GCACAATCCTTGAATGGTGCTATTATTGTAAATCCTTGGAACACCGATGATCTTTCTGAT GCCATCAACGAGGCCTTGACTTTGCCCGATGTAAAGAAAGAAGTTAACTGGGAAAAACTT TACAAATACATCTCTAAATACACTTCTGCCTTCTGGGGTGAAAATTTCGTCCATGAATTA TACAGTACATCATCAAGCTCAACAAGCTCCTCTGCCACCAAAAACTGA
Protein Properties
Pfam Domain Function
Protein Residues495
Protein Molecular Weight56147.5
Protein Theoretical pI6.0
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit MTTDNAKAQLTSSSGGNIIVVSNRLPVTITKNSSTGQYEYAMSSGGLVTALEGLKKTYTF KWFGWPGLEIPDDEKDQVRKDLLEKFNAVPIFLSDEIADLHYNGFSNSILWPLFHYHPGE INFDENAWLAYNEANQTFTNEIAKTMNHNDLIWVHDYHLMLVPEMLRVKIHEKQLQNVKV GWFLHTPFPSSEIYRILPVRQEILKGVLSCDLVGFHTYDYARHFLSSVQRVLNVNTLPNG VEYQGRFVNVGAFPIGIDVDKFTDGLKKESVQKRIQQLKETFKGCKIIVGVDRLDYIKGV PQKLHAMEVFLNEHPEWRGKVVLVQVAVPSRGDVEEYQYLRSVVNELVGRINGQFGTVEF VPIHFMHKSIPFEELISLYAVSDVCLVSSTRDGMNLVSYEYIACQEEKKGSLILSEFTGA AQSLNGAIIVNPWNTDDLSDAINEALTLPDVKKEVNWEKLYKYISKYTSAFWGENFVHEL YSTSSSSTSSSATKN
References
External Links
ResourceLink
Saccharomyces Genome Database TPS1
Uniprot IDQ00764
Uniprot NameTPS1_YEAST
GenBank Gene IDAF061037
Genebank Protein ID3150451
General Reference
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