Rho1 guanine nucleotide exchange factor TUS1 (Q06412)

Identification
NameRho1 guanine nucleotide exchange factor TUS1
Synonyms
  • TOR unique function suppressor protein 1
Gene NameTUS1
Enzyme ClassNot Available
Biological Properties
General Functionsignal transduction
Specific FunctionGuanine nucleotide-exchange factor (GEF) for RHO1 that stimulates the exchange of RHO1 GDP-bound form into GTP-bound form. Required for signaling of cell wall defects to RHO1.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
cellular bud neck
incipient cellular bud site
Rho guanyl-nucleotide exchange factor activity
regulation of Rho protein signal transduction
signal transduction
fungal-type cell wall organization
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>3924 bp ATGTATCGATATAATAGAAGTTCCCCTTTTGAACGAACACCAGAAAAACGAGTAAGCCGT CAAGAAAGCCAACGAAAGAGCATCGAATTGCCCAAACTGCCACCATTGAATACGAGGAAC TCCTTTTTGGATGATTCTGATAACGGAACAGATAATATCTCAATTGGCTGGACACCAATC AGTGACACCCAGCAATTCCAAAGCCCGGTCCCTCAGGCTTTTACCTTTACATCAAAACAT AGTGCAAGGGGAAACGGTACTAGCTCTTCAGAATCCACACCCAAATCGACAAAGTACGTC AAAGAAAGACGACCACCACCACCGCCACCCCTTTTGTATTCCACTGAATCAATACGGATA GACTCACCCATGGTATCTCCCAGTTCTCAGTCCCGGGAAAGATCACCTAATAAACTATCC TTTATAGGAAACTCAGAGGAACGACATCACATGGAATACATATCTAACCATTCCAGGATC TTAAAATCACCATTTGCGAACGGATTTAGTCCAAATTCCCCTAAATCTCCAAGAGATAGT AGCAAACAGCAGGCTCACTTCTCTGATGAATCAGATCTACGGTGTCATGAAAGAGAAAAA GCTTTACCCCCAATTCCTTTCACTACTACTCTTCTGCTATCTCCTTTTGATGATGAAGAC TCAGAATTTTTTACGAAACCACCACCGCCTCTATCAACATCTAGAAACGTAAGTGGGAAT AGCCGAGTATCAGAAGCCCTAGAAAGTGTTTATTCTGACTCAGATTATACTTTTAATAAC TCAAATGCCAGGCAAAGTAGTTTTAACTCTTTACTAGGAGCCAAGCCATTAGAATTAGCA CCAAGCATTACTGCACCGACACAACCATTTTCAATTCAATCTATCGATGAGCACAAGCTT TATCAATGTGATAATGTTTACAAACTTTCTGCTATTTATGAGTGGATTTTGAAAGTTTAT TTTGAATGGTTTAATGAATGTGTCTTCACGAAAATCGATCTTTTCCAAATTGTTCAATTA CTTTTAGAGTTTCAAATGCCTACAAATTTCGATCAAGATACGATAGACTCAAATGTGGAT AATATTATGGCTTCGTTTATTTCCCAGAAAGCAGTAAGATTCGATATCATTAACGATGAA GAGGTAGCCGTAGTTGTGGGAGGGCTGGATATTACTGGTGTTTTCACCGAACTACTACCG TGCTATTCATTCATCGATAATACTTATGGATCTACAAACTCCCTGATTTGTTATTCCAAC GTTTGCACACATGGCCAAAGCTCTGGCTTCAGAAAAGAAATAAAACTTTCCGAAATCATA AATAAATCAGTTGGACTTTGGACAGAATACTGGCACTTGACTCCAGATGATTTAGCAGAA ATTAATCCCCGTGAAGTACAAAGACAAAGCTTTATATTTGACTTAATTATTTTAGAAGAA AGATCCTTAAACATGGCTACTGCCGCGGTAGAAATCTATGGGAAACGGTTTGACAAATCC CTACTTCCAGATGAGCCTGAGTTCAAGGCATTGGCATTTGATATCTTCGAACCTCTAATA CAATTACATACCGAATTTCTTTTGACGCCAATATTTTGGAAATTAAAAACGAGAGGTAAG TTTATTGATGGCGTTGGAAAAATCTATTCAAAATGGTGTGGTGAAGCCAAGAATATATAT TTGAATTACGCGAAAGCTATGGCAACGGTACACGAAATCATAATGTGGGAGAAGAAAAAC AAGACGAAATTTGTAACATGGCTTAAGGAGATTGATAACTCGGTTGAAATTACAAGATCG AAGATGTATCATGATGTTATATTCTTTGGGGGGTTTTTCAAATCTTTACAAAACATGCCC GTAACTCTGCGCTCAATTTTGAAGAACACGGATCCTTCCATGGAGGATTATGAATACCTG AAAATAGTAATTAAGGAAGTAGAAAAGTTGAACTTTGAAGTTAATCAGGTACATGGATTA GCAATTGACCATAGGAAACTAGTAAGGTTTTCGAAACAATTAGTATTAAGTACTAATAGT AGTAATGCAACAAGCTATGTGAACGTCGGTGGTAGTACTAACGCAAATGACGATGATGCA ATTCAGGATAAACTAGCTCTTGGTTTAACTTATCCGGAAAGGAAGTTAGTACTATCTGGC ACTGTTTATAAAAAGAGGGATTTATGGCTGGACCCAACCCCAGTGTATATCGCATTATTG GACAATTGCTTACTGATTACAGAGGAAATAAGTAAAGGAGAAACTCAAAAATATAAGCTT ATTGAAAGACCTATCCCAATAGATTATTTAAGTCTCGAGAAAAGGAAAATTCCAGGAACA AGTAAACAGCCTCTGAGAAACTACTCTCAGAAAGAACATAAATCCCCAATGCATAATTTT TCGACACCGATTAACTCCATGAGACCTCTGCTTAAAAGTTCTGGAAATCACATGTCAACA GCGTATGGAGATAGAAAGACTAGTAATACTGAAATTTCTAACGCGAATCCAAACACAGAC GAGTTCTCATTTAAGATCAGAAATACAGCCACAGGTGAATCGTTCAAATTTTTTACAGAA AGTGCAGAAGTACTCAACCAATGGATTGATGCTATCATGGAATCTTTTAAAAGAAATGCA GAAAATCATGATTTAAATGCCTTTGAATTTACAGTGTTGAGCTCTGAGTTCGCATACTTC GACAAGGATGCACCGGTGAATCTACCTGTAGCTCCGGAAGGATCAGAAATTGATGTAGCA CTCAAAGCTTACGCTCAAAAAGCAAACAAAGATTCATGTTCATGGAGTAAGACAACACGG ATTCTTTGTTGTGAAGATGTTAAATTCGAGGGCAGAATTTACCTATTTGTGGCTACAACA GACGGTATCTATGTGAAATATAGAGACGATTATGGTAGTGGTTTCGTTAAAATATTAGAA TTAAACGACGTCAAAAGAATGGAAGCCAATGTTAAGTTGGGGCTCTTGTTTGTATTGGAT AACAGAAAGTTGTGCTATTTTAATATCTCAACGGTAGTGAGCCGTTACCTAGCGCAAGGA AACACTCTAGATGAAAACTGCATTGTGGGAACAGTAATCAGAGATAAGGTGAGATTCTTC AAAATTGCTGATGATTTTGGTAACTCAAAACATTTATTTTTTGAAAGAAAGGGGAAGATA GTTATATTAACACCAGAATTTGATCAATTGACAAACCAAGTAAAATATTTCAAATTTTAC AAAGAGTATAAGCTCCCAAGTTCAAGTAATAACATTCTGAATAACGAAATTGAGGATATT GCCATATTCAGGAAAAGTTTTGCTGTGTGTACAAAGAAAACAGTCATACTTTATCAAGAT TCATTCGAGGATAACGGAATAGTCTTACCATCTTTTTTGAATGATAAAGATATGATGGCA CACTTGAGGCATCCACATTTGAATAGCTTACCGTTCAAAAGTGCTACAGACTCCAAGAAA CGCCCCTCCATAGAATCTCTCACTGAAGAAGCAAAAAAGGATATCGCCACTTGCAAAGCT ATACCGGTCAATTTTTTTCAAATATCACAATCTAGTTTTTTTGCCTTGGTTTATGATGAA GCCGTAGTGAAAATAAACTGCTACGGTGAGATGTCTGATTGGAGAAAGGATATTCTCTTA CTTGATTTTTGTTGTACCGGCGCGAGCTTCCATGGTAATCATTTGATTCTCGTTGGCGAC AATTTGATACAGATTTACGACTTAAAAAATGTTGAGCAGAACCTAGGCGAATTGGTTCCC GTCCAGATCATAAAAGGAAAGAAGATAAAGCTGGCTAGTTCAGAAAGGAGAGAGAAAACA ATTCTTGTGTTAAGTCATCCAAATATACTTAATAGACAATTATTAGTCGCGTGCAATCCT GTAGCAATGGCAGATCATCAATAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1307
Protein Molecular Weight149111.0
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Rho1 guanine nucleotide exchange factor TUS1 MYRYNRSSPFERTPEKRVSRQESQRKSIELPKLPPLNTRNSFLDDSDNGTDNISIGWTPI SDTQQFQSPVPQAFTFTSKHSARGNGTSSSESTPKSTKYVKERRPPPPPPLLYSTESIRI DSPMVSPSSQSRERSPNKLSFIGNSEERHHMEYISNHSRILKSPFANGFSPNSPKSPRDS SKQQAHFSDESDLRCHEREKALPPIPFTTTLLLSPFDDEDSEFFTKPPPPLSTSRNVSGN SRVSEALESVYSDSDYTFNNSNARQSSFNSLLGAKPLELAPSITAPTQPFSIQSIDEHKL YQCDNVYKLSAIYEWILKVYFEWFNECVFTKIDLFQIVQLLLEFQMPTNFDQDTIDSNVD NIMASFISQKAVRFDIINDEEVAVVVGGLDITGVFTELLPCYSFIDNTYGSTNSLICYSN VCTHGQSSGFRKEIKLSEIINKSVGLWTEYWHLTPDDLAEINPREVQRQSFIFDLIILEE RSLNMATAAVEIYGKRFDKSLLPDEPEFKALAFDIFEPLIQLHTEFLLTPIFWKLKTRGK FIDGVGKIYSKWCGEAKNIYLNYAKAMATVHEIIMWEKKNKTKFVTWLKEIDNSVEITRS KMYHDVIFFGGFFKSLQNMPVTLRSILKNTDPSMEDYEYLKIVIKEVEKLNFEVNQVHGL AIDHRKLVRFSKQLVLSTNSSNATSYVNVGGSTNANDDDAIQDKLALGLTYPERKLVLSG TVYKKRDLWLDPTPVYIALLDNCLLITEEISKGETQKYKLIERPIPIDYLSLEKRKIPGT SKQPLRNYSQKEHKSPMHNFSTPINSMRPLLKSSGNHMSTAYGDRKTSNTEISNANPNTD EFSFKIRNTATGESFKFFTESAEVLNQWIDAIMESFKRNAENHDLNAFEFTVLSSEFAYF DKDAPVNLPVAPEGSEIDVALKAYAQKANKDSCSWSKTTRILCCEDVKFEGRIYLFVATT DGIYVKYRDDYGSGFVKILELNDVKRMEANVKLGLLFVLDNRKLCYFNISTVVSRYLAQG NTLDENCIVGTVIRDKVRFFKIADDFGNSKHLFFERKGKIVILTPEFDQLTNQVKYFKFY KEYKLPSSSNNILNNEIEDIAIFRKSFAVCTKKTVILYQDSFEDNGIVLPSFLNDKDMMA HLRHPHLNSLPFKSATDSKKRPSIESLTEEAKKDIATCKAIPVNFFQISQSSFFALVYDE AVVKINCYGEMSDWRKDILLLDFCCTGASFHGNHLILVGDNLIQIYDLKNVEQNLGELVP VQIIKGKKIKLASSERREKTILVLSHPNILNRQLLVACNPVAMADHQ
References
External Links
ResourceLink
Saccharomyces Genome Database TUS1
Uniprot IDQ06412
Uniprot NameTUS1
General ReferenceNot Available