Octanoyltransferase, mitochondrial (Q06005)

Identification
NameOctanoyltransferase, mitochondrial
Synonyms
  • Lipoate biosynthesis protein
  • Lipoate-protein ligase
  • Lipoyl ligase
  • Lipoyl/octanoyl transferase
  • Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Gene NameLIP2
Enzyme ClassNot Available
Biological Properties
General Functionprotein lipoylation
Specific FunctionCatalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
Cellular LocationNot Available
SMPDB Pathways
Lipoic acid metabolismPW002499 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG Pathways
Lipoic acid metabolismec00785 Map00785
SMPDB Reactions
Lipoyl-ACP + apoprotein → Protein N6-(lipoyl)lysine + [ACP]
Octanoyl-[acyl-carrier protein] + apoprotein → Protein N6-(octanoyl)lysine + [ACP]
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
octanoyltransferase activity
lipoate biosynthetic process
protein lipoylation
ligase activity
mitochondrion
lipoyl(octanoyl) transferase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>987 bp ATGTCGAGGTGTATTCGCCAGTCCGTATGCACAAACTTCAATGTCTGTAGGCGACAATGC TTTAGCACTTATGCCTCTGCTCTCAAGGAAATGACACATCCTATAAAACCCTCAGCGCAA ACGCTCAGACATCTACAATTCACTCAAAGAATACCTTTTCAAAAAGGATTGGAAATACAG GAGACATTAGTTAGGGCAAATTTGGACATCAAAGACATTCAATCGAAGATTGAGAGAAAA TTAATACAATTGGATGAAGAATATAAGGGCACTGCAACAATAAATGATAACGAAAAAAGA ATATTAGACAAGGTTATGGCAATGAAACCTAATCCGATAATATTAACGTTTGAGTTTGAG CCAACTTATACAGGTGGGAAGAGGATTAAGAAAACTATGACGCCAGATCAGATAGCGGCT TATGAAAGTTTCATTCCAGAAACGCAAAAGGACAACCCACGACCAAAGTTTGTTCAAGTG GAAAGGGGTGGACAAGTAACATTTCATGGTCCAGGCCAAATTGTTATTTACATTATTTTA GATTTGAAAACATTTCAAAGTTTCCCTGCTAAATGCTTGGTTTCATGCATTGAGCAGGCC ACTATCAGAACGTTGAAGAATACCAAGATGTGCGACGACACTGACAAGCCTTTGAACTTA GATGCTATGACTACAAAGGACACTGGAGTTTGGGTTGAAAATGGCAAGAAGAAAGTTGCT AGTGTTGGAATACACGTCAGACGTTCCATAACATCGCACGGGGTAGCAATTAATGTTAAT ACAGATCTATCGTATATGAATAGTTTTGAAATGTGCGGTTTGAAAAATACACTGACTACT TCAATTATGGAACAACGACCCGATGCTGTTGTAAATGTGCAAAGTGTAGCAATTAGTTTT GTCAAAGAAATGACAAAGCTGCTAGGAATAAAAACTTTGGAAAGAATGCAAATTGACGAC GTCAATATTTTGAAAAAGAATCCGTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues328
Protein Molecular Weight37237.035
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Octanoyltransferase, mitochondrial MSRCIRQSVCTNFNVCRRQCFSTYASALKEMTHPIKPSAQTLRHLQFTQRIPFQKGLEIQ ETLVRANLDIKDIQSKIERKLIQLDEEYKGTATINDNEKRILDKVMAMKPNPIILTFEFE PTYTGGKRIKKTMTPDQIAAYESFIPETQKDNPRPKFVQVERGGQVTFHGPGQIVIYIIL DLKTFQSFPAKCLVSCIEQATIRTLKNTKMCDDTDKPLNLDAMTTKDTGVWVENGKKKVA SVGIHVRRSITSHGVAINVNTDLSYMNSFEMCGLKNTLTTSIMEQRPDAVVNVQSVAISF VKEMTKLLGIKTLERMQIDDVNILKKNP
References
External Links
ResourceLink
Saccharomyces Genome Database LIP2
Uniprot IDQ06005
Uniprot NameLIP2
General ReferenceNot Available