GPI transamidase component GPI17 (Q04080)

Identification
NameGPI transamidase component GPI17
SynonymsNot Available
Gene NameGPI17
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in GPI-anchor transamidase activity
Specific FunctionComponent of the GPI transamidase complex. Involved in transfer of GPI to proteins
Cellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein (Potential)
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO ClassificationNot Available
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1605 bp ATGTCCAATGCAAATCTAAGAAAATGGGTTGGTTTTTGCTTTGTTGCCATTTATCTCTTT TTAGGTGTTCCACTGTGGTACAAGCTAACTACAGTTTATAGAGCATCACTACCAATAAAT TACATTGAGTCACTTCAAAATAACAAATTCCAAGATATTCATCTCGTAATACCGGTGTAT GTTAAGTCAGATACTTACAGATTTCCTGACGTTCATGACGCTATCCAAGTACAAGTTAAC CATTTATTGAATTCTCAGGAGCAACGGGTCCCTTGGTCTTTACAAGTTCTTCCATATAAT GAGACTATTGAGCAGATGGAAAGTGAAGGCAACCAGTTTCATGTCGTTACTTTGAAGTTA GACGAATTTATTGGTTACTCATCAGCTTACGACACCAAAGAAACACTAGTATATTACGAC GATGCTGCCGTTTTAAGTAATGATCTACCGTTTTTTGTTGCTCAAACATTGGTAGAGCAC ACTTTCCAATTGGAATGGACGCATTTGAATAAAACGTGTGAAGGCGTTTCTACAAACAAC GATGTCGCAATATCTTATGATCCAAACATTCATTTAAGTGTAACTTTATTGTCAGGTGAT GGGAATCCTGTTGCATGGGAAATTGAGCCTACATTAACTGACTACTTTTCACCTTTTAGG AAGTTCTTATCACCACTGGTAAATTTTACAGTAGATTCATCCATTGTTTATCATAATGAT TTGAATTTGCATTCATTAAATGGATCATGTACAAGCGTTACGTGGTTTGATCTCTCTCAT ACTATTGATCTTTCTGAACTTTCTTCAATGGCCTATTACCCAGAAGATTCTGCACTGAAT TTAGCCATAGTCTTTCCTAGTGCTTCTTCAAGTCCCGATGGTCTGGCGTTCATTAATGGC ACTCGGATTTCAGACGAAATAACCACATTAGATTGGAATAGTTATCTAGTTCCTCAATGG GGGGTTATAATAATAAATAAAATGCCGTTGAAGCCAAATTCAGTCATTAGCGAAGATTAT TTAGAACCTATGATGTACCGTTTTGCGACAGATATTTTTCAACTATTGGGATTAACGGAG GGCTCGCAAGATTTGTTATCACCTTATATTACCATAGATTCATTCAAAAGGTTGACAATT TTACAGAATCTAGATAAAGCTACGGAAACATTATGGTCGTTAGTGAAATTAACTCAACAA TTTCAGGGCATGTCTATCCCACGCGAAGTATCGGATAATGTTATCGAAGCTTTAGACTTA AGGCTACAGATTATTGATTTATTAAATGATCCTGGAAAGGGTGGAGATATCGTCTGGAAC AATGCCCTGCATCTAAGTAATGAATTGGTTAAACTATGCGAAAAGGCATTTTTCAATGGA GAAATGGTTCAACAAAATTTCTTCCCACAAGAGCACATGATAGCTGTGTATTTACCTTTA TTAGGCCCAATATCGGCAGTCATGTTCTTTGGTTTCTACAACGTGATGAAGGAAAAGAAT CAAAAGAGTAAAAAGAATGGAACCGAGAGAGAAGTTGCTAAAGAAAAATTAGAGTTGAAA GAGGCTCAAAAATTACATGCTATTGATGGTGAAGATGAATTATGA
Protein Properties
Pfam Domain Function
Protein Residues534
Protein Molecular Weight60813.60156
Protein Theoretical pI4.44
Signalling Regions
  • None
Transmembrane Regions
  • 9-29
  • 473-493
Protein Sequence>GPI transamidase component GPI17 MSNANLRKWVGFCFVAIYLFLGVPLWYKLTTVYRASLPINYIESLQNNKFQDIHLVIPVY VKSDTYRFPDVHDAIQVQVNHLLNSQEQRVPWSLQVLPYNETIEQMESEGNQFHVVTLKL DEFIGYSSAYDTKETLVYYDDAAVLSNDLPFFVAQTLVEHTFQLEWTHLNKTCEGVSTNN DVAISYDPNIHLSVTLLSGDGNPVAWEIEPTLTDYFSPFRKFLSPLVNFTVDSSIVYHND LNLHSLNGSCTSVTWFDLSHTIDLSELSSMAYYPEDSALNLAIVFPSASSSPDGLAFING TRISDEITTLDWNSYLVPQWGVIIINKMPLKPNSVISEDYLEPMMYRFATDIFQLLGLTE GSQDLLSPYITIDSFKRLTILQNLDKATETLWSLVKLTQQFQGMSIPREVSDNVIEALDL RLQIIDLLNDPGKGGDIVWNNALHLSNELVKLCEKAFFNGEMVQQNFFPQEHMIAVYLPL LGPISAVMFFGFYNVMKEKNQKSKKNGTEREVAKEKLELKEAQKLHAIDGEDEL
References
External Links
ResourceLink
Saccharomyces Genome Database GPI17
Uniprot IDQ04080
Uniprot NameGPI17_YEAST
GenBank Gene IDU33007
Genebank Protein ID927700
General Reference
  • Jacq, C., Alt-Morbe, J., Andre, B., Arnold, W., Bahr, A., Ballesta, J. P., Bargues, M., Baron, L., Becker, A., Biteau, N., Blocker, H., Blugeon, C., Boskovic, J., Brandt, P., Bruckner, M., Buitrago, M. J., Coster, F., Delaveau, T., del Rey, F., Dujon, B., Eide, L. G., Garcia-Cantalejo, J. M., Goffeau, A., Gomez-Peris, A., Zaccaria, P., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Nature 387:75-78.9169867
  • Ohishi, K., Inoue, N., Kinoshita, T. (2001). "PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8." EMBO J 20:4088-4098.11483512
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
  • Kung, L. A., Tao, S. C., Qian, J., Smith, M. G., Snyder, M., Zhu, H. (2009). "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes." Mol Syst Biol 5:308.19756047