High-osmolarity-induced transcription protein 1 (Q03213)

Identification
NameHigh-osmolarity-induced transcription protein 1
SynonymsNot Available
Gene NameHOT1
Enzyme ClassNot Available
Biological Properties
General FunctionRNA polymerase II transcriptional preinitiation complex assembly
Specific FunctionRequired for a complete transcriptional response to osmotic stress, through recruitment of HOG1 followed by pol II recruitment to the promoters of GPD1 and other HOG-dependent genes.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
cellular hyperosmotic salinity response
RNA polymerase II transcriptional preinitiation complex assembly
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2160 bp ATGTCTGGAATGGGTATTGCGATTCTTTGCATCGTACGTACAAAGATTTATAGGATAACC ATCAGCTTCGATTATTCTACACTGATGAGCCCTTTCTTCTTATTCTTAATGATGCCCACT ACATTAAAGGATGGGTACAGGATGAATAGTCAAGTAAATGAAGATGCTATAGGTATCAAT CTTGACCTCTCACTGCCCACTCACATTTCGCCTACGACTGGTTCAGAGAGCGCCAGTGGC AGTAACGCCAGTACACTTCGCAACGATGGAAATGCACTAGATGGAGGTCTTTTGAGGACT TCAGCAGCGATTTCAGCACCCACAGGTACCAGTCAACCAACAGAAACTATTGGTGAAAAA CTGAGTAATGAAGAGCGGGTGAACTCGAATGTTTCCGCTTCGAACTCGACAACGGCGGGT ACAGGGCGTATGTTAAGCCAATCCTTGACTAATGATTCACCGTCGAACGAAATATCGACG GATCAGTTGAAGATTTTTCAAAGAATGGACGAAATGAGTGCCCGAATGATTGAGATGGAG GAAAGCTTCAACAAGTTATCTAATAAGATCGCGGAACAGAATACAATGGTTTTAAACCTA AAACAAGATAACTATAAAGTTATGAACAAATTGAATATATTACTTAAGTTGGTTGCGCAG CCAAGCGCGCGCCCAAGCACAAACAATGCCCAAAATAAGCTTGCTATCGAATTGCTAAAT TCGATATCAGCCGTTAGTAGTGCTTACTTGCAGAAAATGCAGAATAATGGCTCTGGTAGA CAGCATACTGCTGATTTATGTACAGGAGATTCCAACACCCATTCTGGTATCAACCAGCAT CGGACTACGAATGGAACCATAGATGTGAATACGAATACTGCACAGCTAAACAACCAATTT TCTAACGCACTAAATACTATCTTACCTGATCAGCAGCATAATCGAAATAATGTTTCCCAA AATATAAACCAATCGCTCCCTAACCGACAACTTGGTCCTGTTATAAACACACAAGCCAAT CAGAACCAGTCGCAGGTTTTAATTCATAACACAAATACACATCAGCAGGTAAATCGCTCG CCTATTAGTTTCCCGAACGCTTCAACTGACAAGCCATTCAAGTTGAACCCAAATGGGATT AAACGGCGCAGAAGAAATACGCAAAGTAACAACAATGCGAGCACAAATGACCATGCTAGT GCTGCACAAAAGCCCATATCAGCCCTATCTCCATTAACGAATTCTCATAATTCTACAACT AGCATGAATTATACCAATTCTTCCATTCATTCAGGCGTCACCAGTGCTTCAAATTCATTT CATGACTTAAATTCATTGAATAACTTTGGCACGACAACAGCTTTAAGTTTGCCCAGCTTA GCCCTAGATAACGCTTCTTTTCCCCCAAATCAAAATGTTATACCCCCTATTATAAATAAT ACCCAGCAGCCTCTATCATTTTCCCAATTGATCAATCAGGATAGCACGACATCTGAATTG TTACCGAGTGGTAAGTCAGGGGTGAACACGAATATTGTAAATAGAAACAGAGCTTCTACT CTACCGTCGTACCCAAAACCAATGACAGTGAAAAGTAATGTCGACGATGATGGCTATCAA GAGGATGATGATGATGACGGTGATGACGAAGGTGATGGAAGGGATAATGAAGAAGACAGC ACTGCTGAGGAAGATGAAGTAGATGATGAAATCGAAACAGATATGAAGAACGCTTCGATT AACAAGCGGAGGAGGAGCTTGCATCATAAAAAAAGTAACTCTTTAAACGGTAGAAGAAAG CTTCACGGCGAGTCGGCTACTAAGCCCAACATAAACTCTGATTTACATTATAGGATATTG AAGGCTCCCACTGACGTAAAGACTATATGGGAAGAGTATGATACTGGAATAAGAGGAAAG CCATCGATCAAGCATCTTGAGGCCAAGTATGGTAACAAGTGGAGGCTCAATAAAAATAAG AAGACCTTTTCAAGGCGAAAAAGATTGTACAAGTTCATTCTGAACGGTATGGAGAGAGGT AAAACGGCACAAGAGATGATAGAAACCTTAGAGAACAAAAGGCTATATAAAGATGATGAG GATGGCGAAGTAAAGAAAAGAACCATTGGCTGGTTGCAAGAGAGCCTTGCTGGAATATAG
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues719
Protein Molecular Weight79415.23
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>High-osmolarity-induced transcription protein 1 MSGMGIAILCIVRTKIYRITISFDYSTLMSPFFLFLMMPTTLKDGYRMNSQVNEDAIGIN LDLSLPTHISPTTGSESASGSNASTLRNDGNALDGGLLRTSAAISAPTGTSQPTETIGEK LSNEERVNSNVSASNSTTAGTGRMLSQSLTNDSPSNEISTDQLKIFQRMDEMSARMIEME ESFNKLSNKIAEQNTMVLNLKQDNYKVMNKLNILLKLVAQPSARPSTNNAQNKLAIELLN SISAVSSAYLQKMQNNGSGRQHTADLCTGDSNTHSGINQHRTTNGTIDVNTNTAQLNNQF SNALNTILPDQQHNRNNVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRS PISFPNASTDKPFKLNPNGIKRRRRNTQSNNNASTNDHASAAQKPISALSPLTNSHNSTT SMNYTNSSIHSGVTSASNSFHDLNSLNNFGTTTALSLPSLALDNASFPPNQNVIPPIINN TQQPLSFSQLINQDSTTSELLPSGKSGVNTNIVNRNRASTLPSYPKPMTVKSNVDDDGYQ EDDDDDGDDEGDGRDNEEDSTAEEDEVDDEIETDMKNASINKRRRSLHHKKSNSLNGRRK LHGESATKPNINSDLHYRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLNKNK KTFSRRKRLYKFILNGMERGKTAQEMIETLENKRLYKDDEDGEVKKRTIGWLQESLAGI
References
External Links
ResourceLink
Saccharomyces Genome Database HOT1
Uniprot IDQ03213
Uniprot NameHOT1
General ReferenceNot Available