N-alpha-acetyltransferase, 35 NatC auxiliary subunit (Q02197)

Identification
NameN-alpha-acetyltransferase, 35 NatC auxiliary subunit
Synonyms
  • Glucose repressible protein MAK10
  • L-A virus GAG protein N-acetyltransferase subunit MAK10
  • Maintenance of killer protein 10
  • N-terminal acetyltransferase C complex subunit MAK10
  • NatC complex subunit MAK10
Gene NameMAK10
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in protein binding
Specific FunctionComponent of the NatC N-terminal acetyltransferase, which catalyzes acetylation of the N-terminus Met of L-A virus Gag protein. MAK10 has a role in the propagation of L-A and M viruses, perhaps in the viral assembly. It is apparently directly needed for optimum respiration
Cellular LocationCytoplasm
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO ClassificationNot Available
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2202 bp ATGGAAGTAGACAGTATATTAGGTTCCTTGAGCATAACTGATGATTTTGACCAATTGGTT GACGTCACAAGTCTGTTTGATGAATTGTGTTCAAAACTAAAACCAGAGGCTATCGTGAAA GATCCCAGGTTTGATTTGTTCGAGGGTACACATTCTTTAGAGGTCAACAACTCCAAATTA GACTCCAGTCTGATAGAATTGACAGCAGAAGAAATAGAATTTGATGTGAACGTGGCCTAC GATCCACCGTTGGCAAGTGTAGCAGCCATAGCGGATAGATTACTTAGATGTGTTATCTCC TGGCTGAATGACTACCAGACTTTACCCACTACTGTATTAAGCTGCAGGTATACAGAAAGC TTATTATCGTCATTAGTTAAGGGAACAACTGCCGGTTCGTCCTGGTGTACAGGGAATATT TTGTATGATAAAGTACTAGGAAGTTGCATACTTGGCGTTTGTTATTTAACAAAATTTGTG CAGAAACTCTTGAGTGCTGGTATTGTTTTTGAAGAGGAGGATTTAAATTTTAATAACATG GGGTTTAATACATTCGATAATTTGCCGGGGCAAGATGTTGTTATCAATTCTCTCACCGAG AGCCTTCAGATATTAGAGGCATATTCTGATGATAGCTTACATTTAACTATGCTGAAGCAT ATACTAAAAATTATCATTTGCTTAGTCCACTTAGAAGACCATCTGACAGACTATTCCACA AAGACAAGCCACCTGGATGAGCTAATTGAAAACGCTAACTCGGTTAATGGCATATTTCCA CAATTACAGCTGTCTCCACCAAAGGGTGCGTTCTCAACATATATACAAAAGCACAGGTCT AATCAATTCCCTCCCAGGAAGATTACGAAGTTACCGACGGATTACAGCGGCTTTATTACA CTGGCAAATGATGTTAAAACAATACTCCTTGTAGATAAAGCCGAGTCTGCGTTGGAGACC TACCAGTTTGCCAAATTCTTCAACAAGTTGGAACAAAGGCATGTCATTGCAAGGATCTTA TTCCCCTTATTTTTCATTAGAGACGACAGAACAGTTTTGGGTAAATTTTCATATACCCAA TTTTATTTGCTACATGTCAAGGAGTTTTCAGCACAAACTCCATCTGAATTTGAATCCTCT ATTGGTAATGAACTTATCCAAGAAAGCTCTAATATGCTTTTAGAATGGTACCAAAACTGC TCCCAAAACACATGTAGATATAGACAAGGTTTTAACAGGCAACTTATTCTATGGGATTCT CTTCAAGCCCAGTTTGAAAGTGTCAATTCACAAGTTTACTGTTCGTGGACATATTTTATG AAACTATCAAGTATGATCGAATTCTCTTTAAAGGGGTTTGATTTGGATATTTACAAACCC TTTGAAGCATACTCTATGTTTTGGTATGTTTATTATTTAAGTCACCACTTAGAAACCTTT TTGAAAGATAGTCAAAATGATATTGAATCAAATATTAATGCCATTCATTCCATGAACAAA AAACTTAAAAAATTGAAAGCTGGTGAAAAGAAGGACCAATTGAGGCTAAAGTACAGGTTT GCTATGGATAATGAAATGGAACAATTACAAGCTACCAAACAATTTTTAAACTATCTTTTG AAGGAAATTAACATTACCAAATCTTTATGTCTAATAGAGGTTTTCCAATTTGCAATTTTA AAGTCATTTGGTTTAATTGACAACAAGAATAGTACTCCGTCAAAATTCTCTAATGAACGG TTAATCCATAATTTGAGATTCAAGCCATTTAATTCAATTGGTGTTCCTGAGTTACCAGAA TATGAAGTATTTCAACAAACTTTAAAAGATTTTGTCATTGAAGAAAAAGGAGCTGCATTT GATATAAAGTTAGAAAGGGCCACTAACTTTATCGAAACTGAAGTGCGCAATGTCGTTAGT TCTATTGATGAGATAATGCAAGGAATCAAGGGAGGCGATAATAACGGCGTTCTAGTAACA GGAACAAGACTGGTTCAAGAGCTCTCTCTGGAGTACTATTGTAAACTAAAACATACTTCT AAAGCATTATCAGTCAACTCAAAAGTTATCGTCAACACTTTGAAAAAGAACATTAAAAAC AAGGACTCCCACGAATACAAGGTTGAATTAGTTCATACAACAGAAGGATGGAACTATTTC CCCATACAAACATTGAGAATAAAGCAAGACCGCTATAAATAA
Protein Properties
Pfam Domain Function
Protein Residues733
Protein Molecular Weight84301.60156
Protein Theoretical pI5.67
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>N-alpha-acetyltransferase, 35 NatC auxiliary subunit MEVDSILGSLSITDDFDQLVDVTSLFDELCSKLKPEAIVKDPRFDLFEGTHSLEVNNSKL DSSLIELTAEEIEFDVNVAYDPPLASVAAIADRLLRCVISWLNDYQTLPTTVLSCRYTES LLSSLVKGTTAGSSWCTGNILYDKVLGSCILGVCYLTKFVQKLLSAGIVFEEEDLNFNNM GFNTFDNLPGQDVVINSLTESLQILEAYSDDSLHLTMLKHILKIIICLVHLEDHLTDYST KTSHLDELIENANSVNGIFPQLQLSPPKGAFSTYIQKHRSNQFPPRKITKLPTDYSGFIT LANDVKTILLVDKAESALETYQFAKFFNKLEQRHVIARILFPLFFIRDDRTVLGKFSYTQ FYLLHVKEFSAQTPSEFESSIGNELIQESSNMLLEWYQNCSQNTCRYRQGFNRQLILWDS LQAQFESVNSQVYCSWTYFMKLSSMIEFSLKGFDLDIYKPFEAYSMFWYVYYLSHHLETF LKDSQNDIESNINAIHSMNKKLKKLKAGEKKDQLRLKYRFAMDNEMEQLQATKQFLNYLL KEINITKSLCLIEVFQFAILKSFGLIDNKNSTPSKFSNERLIHNLRFKPFNSIGVPELPE YEVFQQTLKDFVIEEKGAAFDIKLERATNFIETEVRNVVSSIDEIMQGIKGGDNNGVLVT GTRLVQELSLEYYCKLKHTSKALSVNSKVIVNTLKKNIKNKDSHEYKVELVHTTEGWNYF PIQTLRIKQDRYK
References
External Links
ResourceLink
Saccharomyces Genome Database MAK10
Uniprot IDQ02197
Uniprot NameNAA35_YEAST
GenBank Gene IDM94533
Genebank Protein ID171875
General Reference
  • Lee, Y. J., Wickner, R. B. (1992). "MAK10, a glucose-repressible gene necessary for replication of a dsRNA virus of Saccharomyces cerevisiae, has T cell receptor alpha-subunit motifs." Genetics 132:87-96.1398065
  • Dietrich, F. S., Mulligan, J., Hennessy, K., Yelton, M. A., Allen, E., Araujo, R., Aviles, E., Berno, A., Brennan, T., Carpenter, J., Chen, E., Cherry, J. M., Chung, E., Duncan, M., Guzman, E., Hartzell, G., Hunicke-Smith, S., Hyman, R. W., Kayser, A., Komp, C., Lashkari, D., Lew, H., Lin, D., Mosedale, D., Davis, R. W., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome V." Nature 387:78-81.9169868
  • Polevoda, B., Sherman, F. (2001). "NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p." J Biol Chem 276:20154-20159.11274203
  • Huh, W. K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., O'Shea, E. K. (2003). "Global analysis of protein localization in budding yeast." Nature 425:686-691.14562095
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106