Identification
NameMitochondrial distribution and morphology protein 34
Synonyms
  • Mitochondrial outer membrane protein MMM2
Gene NameMDM34
Enzyme ClassNot Available
Biological Properties
General Functionphospholipid transport
Specific FunctionComponent of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
Cellular LocationNot Available
SMPDB Pathways
Cardiolipin BiosynthesisPW002431 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/28:0)PW003484 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/10:0/30:0)PW003501 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/12:0/26:0)PW003502 ThumbThumb?image type=greyscaleThumb?image type=simple
Cardiolipin Biosynthesis CL(10:0/10:0/12:0/28:0)PW003503 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
mitochondrion organization
ERMES complex
integral component of mitochondrial outer membrane
mitochondrial genome maintenance
mitochondrion-ER tethering
phospholipid transport
mitochondrial outer membrane
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1380 bp ATGTCATTTAGATTCAACGAAGCTGTGTTTGGTGATAACTCTTTCAATGAACGAATACGG GAAAAGTTATCTACGGCTTTGAACTCACCGTCTAAAAAGAAATTAGATATCTTGAAAAGC GGAATTAAGGTACAGAAGGTGGATTTTCCTACAATACCACAGCTAGAAATTCTGGACCTA GACATTATCACGCAGCCCAAGTCTCTGGCCAAGGGGATTTGCAAGATTTCATGTAAGGAT GCTATGTTGCGGATACAGACAGTCATAGAGTCGAATCTTTTATTGATTAACGAACAGGAT ACACCCAGCTTTACCATGCCCCAGCTCATCAATAATGGATCGTTCACAATTCCTATAACT ATGACGTTCAGTTCCATCGAGCTAGAAGCCATCACGAATATTTTTGTAAAGAACCCTGGA ATTGGGATATCCTTTAATGACGTTGATTTGGATTTTAAGTTTGATTGTTCTGTAAAAATT CTCCAAAGCACCATTGAGAGAAGGCTAAAAGAGTCCATGCATGTAGTGTTCAAGGATGTT CTTCCTTCTTTGATCTTCAACACGTCACAGAACTGGTTCACCAATCGCGGCGAGAGCACC AGTACCATCCCTGGTAAAAGAGAGCATCATCATCAACAAACTACAATGTCTAGGAATGTA ATCTTGGACGGATCAGATTTTCAAGAGCTTTCTCCAATAAACATGCTACGTCTTTCAAGC ATTGTGTCGTCGAGGTCAACACTGTCACTACATTCCACTGTGATGAATTCTCTTTCCGCT ATACCTGGTTGCTTGGAAAGACAAAACTTGTACAGATTTATATCAAGGATGCCCTCTTTA AACAATTACTACTCTTCGCAATCATTTCCACAACCAAAGTCATCAACCGTATCATCAAAA CAATTGGTAAAGCCATTCTACTGTTCCCACAATCTATTACCTAAAACAGTGTTAGATTCC AGCCAGTACGATTTGGCTACGATAACCAAGATTCAGTCTCGACTTTTCGATAGGAGTAAC AGCAACGACGACAATGCCAAACCAAGGAGAAGAAAGATCAAATGCAAAAAGACCCGCACA CCATCGAACCTACAATCACAAGGAGAACAGGCTGTTGATGATAGTACTGCTATTGAAACA GTTACGTCCACACCGGTCCAAACACCGATACCCGAGCTTGAAGAACAATCTCCCCCATAT TTGAAAACAACAGTATCGATAAGGGATAAATACGTTATACCAGAAAAAATATCGCTAAAT TTGGACTCCAAGAAAGATACATCTAAAAAGAAACCGTTTTACTTCATAGGTTTGAACTCG CAAGAACCTTCAAATAACTGGAAATGGGGCATGGAGGATAGCCCCCCACCATATCATTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues459
Protein Molecular Weight51989.81
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Mitochondrial distribution and morphology protein 34 MSFRFNEAVFGDNSFNERIREKLSTALNSPSKKKLDILKSGIKVQKVDFPTIPQLEILDL DIITQPKSLAKGICKISCKDAMLRIQTVIESNLLLINEQDTPSFTMPQLINNGSFTIPIT MTFSSIELEAITNIFVKNPGIGISFNDVDLDFKFDCSVKILQSTIERRLKESMHVVFKDV LPSLIFNTSQNWFTNRGESTSTIPGKREHHHQQTTMSRNVILDGSDFQELSPINMLRLSS IVSSRSTLSLHSTVMNSLSAIPGCLERQNLYRFISRMPSLNNYYSSQSFPQPKSSTVSSK QLVKPFYCSHNLLPKTVLDSSQYDLATITKIQSRLFDRSNSNDDNAKPRRRKIKCKKTRT PSNLQSQGEQAVDDSTAIETVTSTPVQTPIPELEEQSPPYLKTTVSIRDKYVIPEKISLN LDSKKDTSKKKPFYFIGLNSQEPSNNWKWGMEDSPPPYH
References
External Links
ResourceLink
Saccharomyces Genome Database MDM34
Uniprot IDP53083
Uniprot NameMDM34
General ReferenceNot Available