RHO1 GDP-GTP exchange protein 2 (P51862)

Identification
NameRHO1 GDP-GTP exchange protein 2
SynonymsNot Available
Gene NameROM2
Enzyme ClassNot Available
Biological Properties
General Functionsmall GTPase mediated signal transduction
Specific FunctionStimulates the exchange of RHO1 GDP-bound form into GTP-bound form.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
cellular bud tip
incipient cellular bud site
mating projection tip
positive regulation of endocytosis
regulation of fungal-type cell wall organization
small GTPase mediated signal transduction
Rho guanyl-nucleotide exchange factor activity
regulation of Rho protein signal transduction
signal transducer activity
establishment of cell polarity
phosphatidylinositol-4,5-bisphosphate binding
activation of GTPase activity
negative regulation of cAMP-mediated signaling
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>4071 bp ATGAGCGAAACCAACGTTGACAGCTTAGGGGACAGAAATGACATATACTCCCAAATATTT GGTGTAGAAAGGAGGCCAGATTCCTTCGCTACTTTTGATAGTGACTCGCACGGAGACATA AGTTCTCAGCTGCTGCCTAATAGAATCGAAAATATCCAGAATCTAAATGTTCTGCTTTCT GAAGACATTGCTAATGACATCATTATTGCCAAGCAGAGGAGACGTTCTGGAGTTGAAGCC GCCATCGATGATTCTGATATACCAAATAACGAAATGAAGGGGAAAAGCTCAAATTACATT TTATCGCAGCAGACTAATATTAAGGAAGTTCCAGATACACAAAGTTTGTCTAGTGCTGAT AATACACCTGTGAGCAGTCCAAAGAAGGCAAGAGATGCCACATCTTCCCATCCCATTGTT CATGCTAAATCGATGTCCCATATATATTCAACGAGTAATAGTGCTAGTAGACAAGCCAAG CACTATAATGACCACCCTTTGCCTCCAATGTCTCCAAGAAATGAAGTTTACCAGAAGAAT AAAAGTACTACAGCTTTTGTGCCTAAGAGGAAACCTTCGCTCCCGCAACTAGCACTTGCT GGTCTTAAGAAGCAGAGCAGTTTTTCCACCGGCAGTGCATCAACCACTCCTACACAGGCT AGAAAATCGCCTTTGCAAGGGTTTGGTTTCTTTTCGAGACCAAGTTCCAAAGACTTGCAC GAACAGCACCAACATCACCAGCATATTCAGCATAATAATATTAACAATCATAATAATAAT AATACTAATAATAATGGCGCACATTATCAAGTGGGTAGTAGTAACAGTAATTACCCTCAA CATTCACATTCTATATCATCTAGATCGATGTCGTTGAACTCATCTACTCTAAAAAATATT GCATCATCTTTTCAATCGAAGACTTCTAACAGCAGGAAAGCTACGCAAAAATATGATATA ACTTCCAACCCATTCTCAGATCCTCATCATCATCATCATCATCATCACTCTTCAAACAGT CACAGTAGCCTAAATAATGTCCACGGGTCTGGAAACTCCTCAAGTGTTATGGGAAGCTCG TCTAATATTGGGTTGGGTCTTAAAACGAGAGTTTCTTCCACCTCATTAGCTTTAAAAAGA TACACTTCGGTTTCAGGAACTTCTCTATCTTCTCCACGTAGAAGTAGTATGACACCTTTG TCGGCATCTAGACCTGTTATGAGCGCTTCATCAAAAAAACCTCAGGTATATCCAGCTTTG TTGTCAAGAGTCGCCACAAAATTTAAAAGTTCGATACAACTCGGGGAACATAAGAAGGAT GGATTAGTTTACCGTGACGCATTTACAGGGCAGCAGGCAGTCGATGTCATCTGTGCTATC ATTAGAACTTCTGATAGAAACTTAGCCTTGTTATTTGGTAGATCACTAGATGCACAAAAG CTGTTCCATGATGTGGTATACGAGCACAGGTTAAGAGATTCACCACATGAAGTTTACGAA TTTACAGATAACTCAAGATTTACAGGAACAGGTTCCACAAACGCCCATGATCCACTGATG CTACTCCCAAACTCATCATCTTTTAATTCCGGGAACCACTCTTATCCGAATTCCGGAATG GTTCCATCAAGTTCAACTTCATCTTTGAATAGTGATCAGGCAACTTTGACAGGGTCGAGG CTACATATGAGTAGTTCATTGTCCCAGCAAAAGAACCCTGCAGCCATTCATAACGTCAAT GGTGTGTTTACATTACTGGCGGAATGCTATTCCCCTACGTGCACAAGAGACGCTTTGTGT TACTCTATTTCGTGTCCAAGACGTCTTGAGCAACAAGCAAGGTTAAATCTGAAACCAAAT GGCGGCCTGAAACGTAATATATCAATGGCATTGGATGATGATGACGAAGAAAAGCCATCT TGGACAAGTTCCGTATCTAAAGAGGATTGGGAAAACTTACCAAAAAAGGAAATAAAAAGA CAAGAGGCTATTTATGAAGTTTATATCACGGAGAAGAACTTTGTAAAATCATTAGAAATT ACAAGAGACACATTCATGAAGACTTTGGCTGAAACAAATATTATTTCAGCAGATATTAGA AAAAATTTCATCAAGCATGTTTTTGCACATATAAACGATATCTATTCAGTGAATAGACGT TTTTTGAAGGCTTTAACTGATAGGCAAAGAAGTTCACCAGTTGTGAGAGGAATTGGGGAC ATTGTTTTAAGATTCATTCCATTTTTTGAACCATTTGTTTCATATGTCGCTTCAAGACCA TATGCGAAGTACTTGATTGAAACCCAAAGATCAGTCAATCCCTATTTTGCTAGATTTGAT GACGATATGATGAGCTCCTCCTTACGTCATGGTATTGATTCGTTTTTATCTCAAGGTGTT TCAAGACCAGGTCGATATATGCTATTGGTCAAAGAAATCATGAAATCTACTGACCCCGAG AAGGACAAAAGTGATTATGAAGATTTAAGCAAAGCCATGGATGCATTAAGGGATTTTATG AAAAGGATTGATCAAGCAAGTGGTGCTGCACAAGATAGACATGATGTAAAATTGTTGAAA CAAAAGATTCTTTTCAAAAACGAATACGTTAATTTAGGATTAAATGACGAAAGGAGAAAA ATTAAACATGAAGGTATACTATCACGGAAGGAGTTGTCAAAATCGGACGGAACAGTTGTT GGTGACATACAATTTTATCTTCTAGATAATATGCTCTTATTTTTAAAGGCCAAAGCAGTT AATAAATGGCACCAGCATAAGGTATTCCAAAGGCCCATTCCATTGCCATTGTTATTTGCA TGTCCAGGTGAAGATATGCCTGCGTTGAGGAAATATATTGGAGACCACCCAGATTGTTCA GGAACTGTAATTCAACCAGAATACAACACGAGTAATCCTAAAAACGCAATAACTTTCTTA TACTACGGTGCCAAGCAGAGATATCAAGTTACATTATATGCTGCGCAATACGCTGGATTG CAAACGCTTTTGGAAAAAATAAAGCAAGGACAAGCAGCTATTATAAGCAAAACGGAGATG TTCAATGTAACGAAAATGAGCGATAGGTTCTTCGATTACACCAACAAAATTAACAGTGTT ACTTCCTGTGATGGGGGTAGAAAACTTCTGATTGCAACGAACTCTGGATTGTATATGAGC AACATTAAAAGACAGCAGAATAAAGATCATAGACATAAAAGCTCTGCTTTTTTTTCAACT CCAATCCAACTAGTACAAAGAAATAATATCACTCAAATTGCTGTATTAGAAGAATTCAAA TCAATCATACTTTTAATTGATAAAAAATTATACAGTTGTCCGCTGTCATTAATCGAAGCA GAAGGTAATGGGACATCTTTCTTCAAAAAGCATCACAAGGAACTGATCAATCATGTGAGT TTCTTCGCAGAAGGAGATTGCAATGGTAAGAGATTAATCGTGACTGCACACAGTTCATCG CATTCAATTAAGTACTTCGAGCATGAACATCCATTATTGGCCGAAAAAAATGGTAGTGGT AGCGGTAACAAAAAAAGTCTCAAGAAAAAAATCACCGAGGTTATTTTTGATTCTGAACCT GTCTCTATTTCATTTCTCAAGGCCAACCTATGCATTGGCTGTAAAAAGGGTTTTCAGATC GTTAGCATTTCACAGAATGCTCATGAATCCTTGTTAGATCCGGCCGATACATCATTAGAG TTTGCACTAAGGGATACTTTGAAACCAATGGCAATCTATCGTGTGGGAAATATGTTTTTG CTGTGTTACACAGAATTTGCCTTCTTTGTCAATAATCAGGGTTGGAGAAAGAAAGAATCG CATATTATTCATTGGGAGGGAGAGCCCCAAAAATTTGCAATTTGGTACCCGTACATCTTG GCATTCGACAGCAACTTCATTGAGATCAGAAAGATTGAAACTGGCGAATTAATTCGTTGC GTCCTTGCTGATAAGATTCGACTTCTACAAACAAGTACTCAAGAAATCCTGTACTGCTAC GAGGATTATCGCGGGTATGATACAGTTGCGTCGTTAGATTTCTGGGGTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1356
Protein Molecular Weight152594.615
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>RHO1 GDP-GTP exchange protein 2 MSETNVDSLGDRNDIYSQIFGVERRPDSFATFDSDSHGDISSQLLPNRIENIQNLNVLLS EDIANDIIIAKQRRRSGVEAAIDDSDIPNNEMKGKSSNYILSQQTNIKEVPDTQSLSSAD NTPVSSPKKARDATSSHPIVHAKSMSHIYSTSNSASRQAKHYNDHPLPPMSPRNEVYQKN KSTTAFVPKRKPSLPQLALAGLKKQSSFSTGSASTTPTQARKSPLQGFGFFSRPSSKDLH EQHQHHQHIQHNNINNHNNNNTNNNGAHYQVGSSNSNYPQHSHSISSRSMSLNSSTLKNI ASSFQSKTSNSRKATQKYDITSNPFSDPHHHHHHHHSSNSHSSLNNVHGSGNSSSVMGSS SNIGLGLKTRVSSTSLALKRYTSVSGTSLSSPRRSSMTPLSASRPVMSASSKKPQVYPAL LSRVATKFKSSIQLGEHKKDGLVYRDAFTGQQAVDVICAIIRTSDRNLALLFGRSLDAQK LFHDVVYEHRLRDSPHEVYEFTDNSRFTGTGSTNAHDPLMLLPNSSSFNSGNHSYPNSGM VPSSSTSSLNSDQATLTGSRLHMSSSLSQQKNPAAIHNVNGVFTLLAECYSPTCTRDALC YSISCPRRLEQQARLNLKPNGGLKRNISMALDDDDEEKPSWTSSVSKEDWENLPKKEIKR QEAIYEVYITEKNFVKSLEITRDTFMKTLAETNIISADIRKNFIKHVFAHINDIYSVNRR FLKALTDRQRSSPVVRGIGDIVLRFIPFFEPFVSYVASRPYAKYLIETQRSVNPYFARFD DDMMSSSLRHGIDSFLSQGVSRPGRYMLLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFM KRIDQASGAAQDRHDVKLLKQKILFKNEYVNLGLNDERRKIKHEGILSRKELSKSDGTVV GDIQFYLLDNMLLFLKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDHPDCS GTVIQPEYNTSNPKNAITFLYYGAKQRYQVTLYAAQYAGLQTLLEKIKQGQAAIISKTEM FNVTKMSDRFFDYTNKINSVTSCDGGRKLLIATNSGLYMSNIKRQQNKDHRHKSSAFFST PIQLVQRNNITQIAVLEEFKSIILLIDKKLYSCPLSLIEAEGNGTSFFKKHHKELINHVS FFAEGDCNGKRLIVTAHSSSHSIKYFEHEHPLLAEKNGSGSGNKKSLKKKITEVIFDSEP VSISFLKANLCIGCKKGFQIVSISQNAHESLLDPADTSLEFALRDTLKPMAIYRVGNMFL LCYTEFAFFVNNQGWRKKESHIIHWEGEPQKFAIWYPYILAFDSNFIEIRKIETGELIRC VLADKIRLLQTSTQEILYCYEDYRGYDTVASLDFWG
References
External Links
ResourceLink
Saccharomyces Genome Database ROM2
Uniprot IDP51862
Uniprot NameROM2
General ReferenceNot Available