GPI transamidase component GAB1 (P41733)

Identification
NameGPI transamidase component GAB1
Synonyms
  • Cell division control protein 91
Gene NameGAB1
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in cell cycle
Specific FunctionComponent of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI
Cellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein (Potential)
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Component
organelle membrane
endoplasmic reticulum membrane
cell part
membrane
membrane part
intrinsic to membrane
integral to membrane
Process
protein amino acid lipidation
GPI anchor biosynthetic process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1185 bp ATGGATTCCACAGCACTTAAGGTAGCTCTAGGCTGTATTGCAATTCGTTTGGCTGTGAAC AGCCTTTTTCCCTCTCTACAACAACAACTGGACCAGTCTGTAGAATTCTCAACTCCCGTA ACTTCATTTAGGTCACTACAGGAAGGTATATACCTACTGCGGAACAACATCCAAGTATAT AATCATGGGGTTGTTCACCATCCTCCAATTTTGATTTTTTTTCTTTCCCTCTTTAATTCC GACAGGTTAATTTCCCTCATATACGCTTTAATTGATGGATTAATTGCGTATCAGCTGACA GAGGTAACAAAGGCTTTCAAAAACTTGAAACTGAAAGTTTGGCTACCTGGACTTCTTTAT GCCGTGAATCCTTTGACCCTTTTATCGTGCATTAGTCGGTCATCAATCATATTCACAAAT TTTGCTATTTCATCGTCATTGTATTGCATATTAGCTGAAGGAAACGTTCTTTTGTCCTCT GTTATGATTTCTATATCTGGATATTTGTCAGTATACCCTATTCTCCTCTTAATTCCGCTA TTAGGTATGCTGAAAAGTTGGAGGCAAAGAATATTATCTGCCATTGTTTCCATACTATCT TTATTAATTCTGCTATTATTCAGCTACAGTATATTAGGCAGCCAAAGTTGGTCATTTTTG ACACAGGTTTATGGATCTATTATAACCTTTGAGAAGGTTTTTCCAAATCTGGGTTTGTGG TGGTACTTCTTCATTGAAATGTTTGACACCTTCATACCGTTCTTCAAGGCTGTATTCAAC ATTTTTATTGCAGTATTCATTACACCATTTACTTTGCGCTATCATAAGCAGCCATTCTAC GCATTCATTTTATGCATTGGGTGGATTGTCCTTACAAAGCCATATCCCTCACTAGGTGAC GCTGGTTTTTTCTTCAGCTTCCTACCTTTCTTCACGCCACTATTTGGATATTTAAGATAC CCCATCATATCAGCATTACTGTTTTTACACGCAATTGTTTTGGCGCCAATTTTCTATCAT CTTTGGGTTGTTTTAGGTTCAGGGAATAGTAATTTTTTCTATGCTATTTCCCTAGTTTAT GCTCTGGCTATAGCATCTATATTAGTTGACTTGAACTGGGCGATGCTGAGAATTGAATAC GATAACGGTATCCCAAATTTCAAATTGAAGGTAACACAAATTTAA
Protein Properties
Pfam Domain Function
Protein Residues394
Protein Molecular Weight44740.69922
Protein Theoretical pI9.25
Signalling Regions
  • None
Transmembrane Regions
  • 136-156
  • 161-181
  • 191-211
  • 225-245
  • 251-271
  • 298-318
  • 325-345
  • 352-372
Protein Sequence>GPI transamidase component GAB1 MDSTALKVALGCIAIRLAVNSLFPSLQQQLDQSVEFSTPVTSFRSLQEGIYLLRNNIQVY NHGVVHHPPILIFFLSLFNSDRLISLIYALIDGLIAYQLTEVTKAFKNLKLKVWLPGLLY AVNPLTLLSCISRSSIIFTNFAISSSLYCILAEGNVLLSSVMISISGYLSVYPILLLIPL LGMLKSWRQRILSAIVSILSLLILLLFSYSILGSQSWSFLTQVYGSIITFEKVFPNLGLW WYFFIEMFDTFIPFFKAVFNIFIAVFITPFTLRYHKQPFYAFILCIGWIVLTKPYPSLGD AGFFFSFLPFFTPLFGYLRYPIISALLFLHAIVLAPIFYHLWVVLGSGNSNFFYAISLVY ALAIASILVDLNWAMLRIEYDNGIPNFKLKVTQI
References
External Links
ResourceLink
Saccharomyces Genome Database GAB1
Uniprot IDP41733
Uniprot NameCDC91_YEAST
GenBank Gene IDL31649
Genebank Protein ID469466
General Reference
  • Hong, Y., Ohishi, K., Kang, J. Y., Tanaka, S., Inoue, N., Nishimura, J., Maeda, Y., Kinoshita, T. (2003). "Human PIG-U and yeast Cdc91p are the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins." Mol Biol Cell 14:1780-1789.12802054
  • Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
  • Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258