Dual-specificity protein phosphatase SDP1 (P40479)

Identification
NameDual-specificity protein phosphatase SDP1
Synonyms
  • Stress-inducible MAPK phosphatase
Gene NameSDP1
Enzyme ClassNot Available
Biological Properties
General Functionregulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
Specific FunctionMediates dephosphorylation of MAPK substrates such as SLT2, acquiring enhanced catalytic activity under oxidative conditions.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
inactivation of MAPK activity involved in cell wall organization or biogenesis
MAP kinase tyrosine/serine/threonine phosphatase activity
MAP kinase tyrosine phosphatase activity
regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
nucleus
cytoplasm
MAPK cascade involved in cell wall organization or biogenesis
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>630 bp ATGAACATATACACATCACCCACGCGAACACCGAACATCGCACCAAAGAGTGGCCAAAGA CCATCTCTTCCTATGCTGGCCACAGATGAGAGGTCTACGGACAAAGAAAGCCCGAATGAA GACCGTGAATTCGTGCCTTGTTCGAGTTTGGACGTGCGCAGAATCTACCCAAAAGGCCCA TTACTTGTTCTCCCGGAAAAGATCTACCTTTATTCAGAGCCCACGGTAAAAGAGCTTTTA CCCTTTGATGTGGTCATCAACGTTGCTGAAGAGGCAAACGATTTACGAATGCAGGTTCCT GCTGTCGAGTACCATCACTACCGATGGGAACATGATTCGCAGATTGCGTTGGACTTGCCA TCATTGACTAGCATCATACACGCAGCTACGACTAAGCGAGAGAAGATACTGATACATTGC CAATGTGGGCTGTCGAGATCCGCAACGCTGATTATTGCATATATAATGAAATATCATAAC TTGAGTCTGAGGCACTCATATGATCTGTTGAAATCAAGGGCAGACAAGATAAACCCTTCC ATAGGGCTTATTTTCCAGTTGATGGAATGGGAGGTTGCTCTTAACGCGAAGACTAACGTG CAAGCCAACAGTTATAGAAAAGTACCGTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues209
Protein Molecular Weight23885.22
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Dual-specificity protein phosphatase SDP1 MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLDVRRIYPKGP LLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLP SLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPS IGLIFQLMEWEVALNAKTNVQANSYRKVP
References
External Links
ResourceLink
Saccharomyces Genome Database SDP1
Uniprot IDP40479
Uniprot NameSDP1
PDB ID
2J16
General ReferenceNot Available