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Putative pterin-4-alpha-carbinolamine dehydratase (P38744)

Identification
NamePutative pterin-4-alpha-carbinolamine dehydratase
Synonyms
  • PHS
  • 4-alpha-hydroxy-tetrahydropterin dehydratase
  • Pterin carbinolamine dehydratase
  • PCD
Gene NameNot Available
Enzyme Class
Biological Properties
General FunctionInvolved in 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Specific Function(6R)-6-(L-erythro-1,2-dihydroxypropyl)- 5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2- dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O
Cellular LocationNot Available
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00030DihydrobiopterinShow
YMDB00984(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterinShow
GO Classification
Component
Not Available
Function
carbon-oxygen lyase activity
hydro-lyase activity
4-alpha-hydroxytetrahydrobiopterin dehydratase activity
catalytic activity
lyase activity
Process
cellular biosynthetic process
heterocycle biosynthetic process
pteridine and derivative biosynthetic process
tetrahydrobiopterin biosynthetic process
metabolic process
biosynthetic process
Gene Properties
Chromosome LocationNot Available
LocusYHL018W
Gene Sequence>363 bp ATGCACAACAAGATTGTTAGAATCGCGTCCAGTGCACTCACAGGGGGCAAACTACTCGAG AAGCTAAAACCCTTGACCCGTTGGGAAGTTCAATGGGACCCTAATAAGACCAAATGTTTG GGAATAACAAGAGAGGTAACATTCAAGGACTACGAAACCACATGGGCCTTTTTGACTCGT GTATCGATGAGATCTCATCTATGGGGCCACCATCCCCTGATTCACACAAGTTACACCTGG GTCAAGCTGGAACTTCATACGCATGACATAGACCCGAAAGACGGGGCTCACAGCCAGCTT AGCGATATAGACGTCCGGATGGCCAAGAGAATAGATTCCTACATCGATGAGATGACAACT TGA
Protein Properties
Pfam Domain Function
Protein Residues120
Protein Molecular Weight14026.0
Protein Theoretical pI9.09
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Putative pterin-4-alpha-carbinolamine dehydratase MHNKIVRIASSALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITREVTFKDYETTWAFLTR VSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSDIDVRMAKRIDSYIDEMTT
References
External Links
ResourceLink
Saccharomyces Genome Database YHL018W
Uniprot IDP38744
Uniprot NamePHS_YEAST
GenBank Gene IDAY558391
Genebank Protein ID45270672
General Reference
  • Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
  • Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106