Putative pterin-4-alpha-carbinolamine dehydratase (P38744)

Identification
NamePutative pterin-4-alpha-carbinolamine dehydratase
Synonyms
  • PHS
  • 4-alpha-hydroxy-tetrahydropterin dehydratase
  • Pterin carbinolamine dehydratase
  • PCD
Gene NameNot Available
Enzyme Class
Biological Properties
General FunctionInvolved in 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Specific Function(6R)-6-(L-erythro-1,2-dihydroxypropyl)- 5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2- dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O
Cellular LocationNot Available
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
YMDB00030DihydrobiopterinShow
YMDB00984(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterinShow
GO Classification
Component
Not Available
Function
catalytic activity
lyase activity
carbon-oxygen lyase activity
hydro-lyase activity
4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Process
metabolic process
biosynthetic process
cellular biosynthetic process
heterocycle biosynthetic process
pteridine and derivative biosynthetic process
tetrahydrobiopterin biosynthetic process
Gene Properties
Chromosome LocationNot Available
LocusYHL018W
Gene Sequence>363 bp ATGCACAACAAGATTGTTAGAATCGCGTCCAGTGCACTCACAGGGGGCAAACTACTCGAG AAGCTAAAACCCTTGACCCGTTGGGAAGTTCAATGGGACCCTAATAAGACCAAATGTTTG GGAATAACAAGAGAGGTAACATTCAAGGACTACGAAACCACATGGGCCTTTTTGACTCGT GTATCGATGAGATCTCATCTATGGGGCCACCATCCCCTGATTCACACAAGTTACACCTGG GTCAAGCTGGAACTTCATACGCATGACATAGACCCGAAAGACGGGGCTCACAGCCAGCTT AGCGATATAGACGTCCGGATGGCCAAGAGAATAGATTCCTACATCGATGAGATGACAACT TGA
Protein Properties
Pfam Domain Function
Protein Residues120
Protein Molecular Weight14026.0
Protein Theoretical pI9.09
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Putative pterin-4-alpha-carbinolamine dehydratase MHNKIVRIASSALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITREVTFKDYETTWAFLTR VSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSDIDVRMAKRIDSYIDEMTT
References
External Links
ResourceLink
Saccharomyces Genome Database YHL018W
Uniprot IDP38744
Uniprot NamePHS_YEAST
GenBank Gene IDAY558391
Genebank Protein ID45270672
General Reference
  • Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
  • Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106