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Identification |
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Name | Exopolyphosphatase |
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Synonyms | - ExopolyPase
- Metaphosphatase
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Gene Name | PPX1 |
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Enzyme Class | |
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Biological Properties |
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General Function | Involved in pyrophosphatase activity |
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Specific Function | Degradation of inorganic polyphosphates |
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Cellular Location | Cytoplasmic |
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SMPDB Pathways | Not Available |
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KEGG Pathways | |
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SMPDB Reactions | Not Available |
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KEGG Reactions | Not Available |
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Metabolites | YMDB ID | Name | View |
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YMDB00907 | phosphate | Show |
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GO Classification | Component |
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cell part | intracellular part | cytoplasm | Function |
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binding | ion binding | cation binding | metal ion binding | transition metal ion binding | hydrolase activity | hydrolase activity, acting on acid anhydrides | manganese ion binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | pyrophosphatase activity | catalytic activity | Process |
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Not Available |
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Gene Properties |
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Chromosome Location | chromosome 8 |
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Locus | YHR201C |
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Gene Sequence | >1194 bp
ATGTCGCCTTTGAGAAAGACGGTTCCTGAATTTTTGGCACACTTAAAATCACTGCCAATT
TCAAAAATTGCAAGCAACGATGTGTTAACAATATGTGTTGGTAACGAATCAGCAGATATG
GACTCAATTGCTAGTGCAATCACTTATTCGTACTGCCAATACATATATAATGAAGGTACT
TACTCGGAGGAGAAAAAGAAAGGAAGCTTTATTGTCCCAATTATCGACATTCCTAGGGAA
GACCTCAGTTTAAGAAGAGACGTAATGTATGTCCTAGAAAAACTGAAAATTAAGGAGGAG
GAATTATTCTTCATTGAAGATTTAAAGAGCTTGAAGCAAAATGTCTCCCAGGGTACTGAA
TTAAACTCTTACTTGGTAGATAATAACGATACACCAAAGAATTTGAAAAATTATATAGAT
AACGTCGTTGGCATTATAGACCACCATTTTGACTTGCAAAAACATTTGGATGCTGAACCT
CGGATTGTAAAAGTATCCGGCAGTTGCTCATCGCTGGTTTTTAACTACTGGTATGAAAAA
TTGCAAGGTGACCGTGAAGTGGTGATGAACATTGCACTACTTTTGATGGGGGCCATCTTA
ATAGACACTTCAAATATGAGGCGCAAAGTCGAGGAAAGTGATAAATTAGCTATCGAGAGA
TGCCAAGCTGTTCTTAGTGGTGCGGTTAATGAAGTCTCTGCGCAAGGTTTAGAGGACAGC
AGTGAGTTTTACAAAGAGATAAAATCAAGAAAGAACGATATTAAAGGATTTTCGGTAAGC
GATATTTTAAAGAAGGACTACAAACAATTCAATTTCCAAGGAAAGGGACACAAAGGGTTA
GAGATTGGTTTTTCATCAATAGTAAAAAGAATGTCTTGGCTATTCAATGAACACGGTGGT
GAAGCAGATTTCGTCAACCAGTGCAGAAGATTCCAGGCGGAGAGGGGGCTCGATGTATTG
GTTCTGTTGACTTCATGGAGGAAAGCTGGCGATTCACACAGAGAATTGGTCATATTGGGA
GACTCTAACGTGGTACGTGAACTCATTGAAAGGGTTAGCGACAAGCTCCAACTTCAATTA
TTTGGGGGCAATCTTGATGGAGGTGTGGCGATGTTTAAGCAACTGAACGTCGAGGCCACC
AGAAAGCAAGTCGTCCCCTATTTAGAGGAAGCGTACTCAAACCTGGAAGAGTGA |
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Protein Properties |
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Pfam Domain Function | |
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Protein Residues | 397 |
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Protein Molecular Weight | 45051.0 |
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Protein Theoretical pI | 5.39 |
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Signalling Regions | |
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Transmembrane Regions | |
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Protein Sequence | >Exopolyphosphatase
MSPLRKTVPEFLAHLKSLPISKIASNDVLTICVGNESADMDSIASAITYSYCQYIYNEGT
YSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFFIEDLKSLKQNVSQGTE
LNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQKHLDAEPRIVKVSGSCSSLVFNYWYEK
LQGDREVVMNIAPLLMGAILIDTSNMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDS
SEFYKEIKSRKNDIKGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGG
EADFVNQCRRFQAERGLDVLVLLTSWRKAGDSHRELVILGDSNVVRELIERVSDKLQLQL
FGGNLDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE |
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References |
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External Links | |
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General Reference | - Wurst, H., Shiba, T., Kornberg, A. (1995). "The gene for a major exopolyphosphatase of Saccharomyces cerevisiae." J Bacteriol 177:898-906.7860598
- Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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