Protein SIC1 (P38634)

Identification
NameProtein SIC1
Synonyms
  • CDK inhibitor p40
Gene NameSIC1
Enzyme ClassNot Available
Biological Properties
General Functionregulation of cyclin-dependent protein serine/threonine kinase activity
Specific FunctionSubstrate and inhibitor of the cyclin-dependent protein kinase CDC28. Its activity could be important for faithful segregation of chromosomes to daughter cells. It acts in response to a signal from a post-start checkpoint.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
cytoplasm
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
cyclin-dependent protein serine/threonine kinase inhibitor activity
negative regulation of macroautophagy
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>855 bp ATGACTCCTTCCACCCCACCAAGGTCCAGAGGGACTAGGTACCTTGCGCAGCCTAGTGGC AATACTAGTTCTAGTGCCCTAATGCAAGGTCAAAAGACCCCCCAAAAGCCTTCACAGAAC CTAGTCCCTGTCACTCCCTCAACAACTAAGTCTTTTAAAAATGCGCCATTATTAGCACCT CCCAATTCGAACATGGGTATGACCTCTCCATTTAATGGGCTTACGTCTCCTCAACGCTCG CCGTTTCCAAAATCTTCAGTGAAGAGGACACTATTCCAATTTGAAAGTCATGATAATGGA ACAGTAAGGGAAGAGCAGGAACCATTGGGTCGTGTAAATAGGATATTGTTTCCCACGCAG CAAAATGTGGATATAGATGCAGCAGAAGAAGAAGAAGAAGGAGAAGTTCTTCTTCCCCCC AGCAGACCTACATCTGCCAGGCAGTTACATTTATCACTTGAAAGAGATGAGTTTGATCAG ACACATAGAAAGAAGATTATTAAAGATGTACCTGGTACGCCCAGCGACAAGGTGATAACA TTTGAATTGGCAAAAAATTGGAACAACAACTCTCCGAAAAATGACGCCAGGAGTCAAGAA AGTGAAGACGAGGAAGACATCATCATCAATCCAGTGCGGGTGGGTAAAAATCCCTTTGCA TCAGATGAACTGGTCACTCAGGAAATTAGAAATGAACGTAAAAGGGCAATGTTGAGAGAA AACCCAGATATAGAAGACGTAATAACATATGTCAATAAGAAGGGAGAGGTGGTAGAGAAA CGAAGGTTAACGGATGAAGAAAAGAGAAGATTCAAGCCAAAGGCATTGTTTCAATCTAGG GATCAAGAGCATTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues284
Protein Molecular Weight32222.745
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein SIC1 MTPSTPPRSRGTRYLAQPSGNTSSSALMQGQKTPQKPSQNLVPVTPSTTKSFKNAPLLAP PNSNMGMTSPFNGLTSPQRSPFPKSSVKRTLFQFESHDNGTVREEQEPLGRVNRILFPTQ QNVDIDAAEEEEEGEVLLPPSRPTSARQLHLSLERDEFDQTHRKKIIKDVPGTPSDKVIT FELAKNWNNNSPKNDARSQESEDEEDIIINPVRVGKNPFASDELVTQEIRNERKRAMLRE NPDIEDVITYVNKKGEVVEKRRLTDEEKRRFKPKALFQSRDQEH
References
External Links
ResourceLink
Saccharomyces Genome Database SIC1
Uniprot IDP38634
Uniprot NameSIC1
PDB ID
3V7D
General ReferenceNot Available