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Identification |
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Name | Sedoheptulose 1,7-bisphosphatase |
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Synonyms | Not Available |
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Gene Name | SHB17 |
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Enzyme Class | Not Available |
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Biological Properties |
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General Function | ribosome biogenesis |
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Specific Function | Sedoheptulose 1,7-bisphosphatase involved in riboneogenesis. Dephosphorylates sedoheptulose 1,7-bisphosphate (SBP), which is converted via the non-oxidative pentose phosphate pathway to ribose-5-phosphate. Has a fructose 1,6-bisphosphatase activity in vitro, but this is probably not biologically relevant, since deletion does not affect fructose 1,6-biphosphate (FBP) levels. |
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Cellular Location | Not Available |
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SMPDB Pathways | |
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KEGG Pathways | Not Available |
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SMPDB Reactions | |
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KEGG Reactions | Not Available |
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Metabolites | YMDB ID | Name | View |
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YMDB00196 | D-Sedoheptulose 7-phosphate | Show | YMDB00753 | sedoheptulose 1,7-bisphosphate | Show | YMDB00890 | water | Show | YMDB00907 | phosphate | Show |
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GO Classification | Function |
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oxidoreductase activity | cytosol | nucleus | ribosome biogenesis | sedoheptulose-bisphosphatase activity | carbohydrate metabolic process | ribose phosphate biosynthetic process |
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Gene Properties |
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Chromosome Location | Not Available |
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Locus | |
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Gene Sequence | >816 bp
ATGCCTTCGCTAACCCCCAGATGTATCATTGTCAGACACGGTCAAACTGAATGGTCCAAG
TCAGGCCAGTATACTGGTTTGACAGATCTACCGTTAACGCCCTACGGTGAGGGCCAAATG
TTGAGGACCGGTGAGAGTGTTTTCCGCAATAATCAGTTTTTGAATCCAGACAACATCACT
TATATCTTCACCTCTCCACGTTTGCGTGCCAGGCAAACTGTGGATTTGGTTTTGAAACCA
TTAAGCGACGAGCAAAGAGCTAAGATCCGTGTGGTGGTAGACGACGACTTGCGAGAGTGG
GAGTACGGTGACTACGAGGGAATGCTGACTCGAGAAATCATTGAATTGAGAAAGTCACGC
GGTTTGGACAAGGAGAGGCCATGGAATATCTGGAGAGATGGGTGTGAGAACGGTGAGACT
ACTCAGCAAATTGGGTTGAGACTTTCCCGCGCTATTGCCAGAATCCAGAACTTGCACCGC
AAGCACCAGAGTGAGGGCAGAGCATCAGACATCATGGTCTTTGCGCACGGACATGCATTG
CGTTATTTTGCTGCTATTTGGTTTGGACTGGGTGTGCAAAAGAAGTGTGAGACGATTGAA
GAAATTCAAAATGTCAAATCTTATGATGACGACACAGTTCCATATGTGAAATTGGAATCT
TACAGACATTTGGTAGACAATCCATGTTTCTTACTGGACGCCGGTGGGATTGGTGTTTTG
TCATACGCTCACCACAACATTGACGAACCTGCATTGGAATTAGCAGGTCCATTTGTCTCA
CCACCAGAGGAGGAATCCCAGCATGGCGATGTGTAA |
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Protein Properties |
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Pfam Domain Function | Not Available |
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Protein Residues | 271 |
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Protein Molecular Weight | 31021.71 |
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Protein Theoretical pI | Not Available |
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PDB File | show |
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Signalling Regions | Not Available |
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Transmembrane Regions | Not Available |
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Protein Sequence | >Sedoheptulose 1,7-bisphosphatase
MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQFLNPDNIT
YIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREIIELRKSR
GLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHRKHQSEGRASDIMVFAHGHAL
RYFAAIWFGLGVQKKCETIEEIQNVKSYDDDTVPYVKLESYRHLVDNPCFLLDAGGIGVL
SYAHHNIDEPALELAGPFVSPPEEESQHGDV |
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References |
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External Links | |
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General Reference | Not Available |
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