Protein phosphatase 2C homolog 1 (P35182)

Identification
NameProtein phosphatase 2C homolog 1
Synonyms
  • PP2C-1
Gene NamePTC1
Enzyme ClassNot Available
Biological Properties
General FunctiontRNA splicing, via endonucleolytic cleavage and ligation
Specific FunctionIt has a serine and a weak tyrosine phosphatase activity with ratios of serine to tyrosine phosphatase activity as high as 200:1. It is essential for growth or germination at 37 degrees Celsius. May have a role in the heat shock response. Involved in tRNA splicing and cell separation.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
metal ion binding
pheromone-dependent signal transduction involved in conjugation with cellular fusion
nucleus
cytoplasm
protein serine/threonine phosphatase activity
protein dephosphorylation
inactivation of MAPK activity involved in osmosensory signaling pathway
mitochondrion inheritance
tRNA splicing, via endonucleolytic cleavage and ligation
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>846 bp ATGAGTAATCATTCTGAAATCTTAGAAAGGCCAGAAACACCATATGACATAACTTATAGA GTAGGTGTGGCGGAAAATAAAAACTCGAAATTTCGGAGGACAATGGAAGATGTTCATACG TATGTTAAAAACTTTGCTTCAAGATTAGATTGGGGATATTTCGCGGTGTTTGATGGACAT GCTGGGATTCAGGCCTCCAAATGGTGTGGTAAACATCTTCATACAATTATAGAGCAAAAC ATTTTGGCAGATGAAACACGAGATGTTAGAGATGTATTGAACGATTCATTCCTAGCCATT GACGAAGAAATTAATACAAAACTTGTAGGAAATAGTGGATGTACTGCTGCTGTTTGCGTA TTACGTTGGGAGCTTCCGGATTCAGTTTCTGATGATTCAATGGATTTAGCCCAACACCAA AGAAAGTTATATACAGCAAATGTTGGTGATTCTCGAATAGTATTGTTTAGAAACGGGAAC AGCATAAGACTGACTTATGATCATAAGGCATCTGACACTTTGGAGATGCAGAGAGTTGAA CAAGCAGGTGGCCTGATAATGAAAAGTCGTGTAAATGGTATGCTGGCAGTGACGAGATCG TTAGGGGATAAATTTTTTGATAGTTTAGTAGTGGGCAGCCCATTTACCACGAGCGTAGAA ATAACTTCTGAGGACAAATTTTTAATCCTAGCGTGTGATGGATTATGGGATGTTATTGAT GATCAAGATGCATGCGAATTAATCAAGGATATTACTGAACCTAATGAAGCTGCAAAAGTC TTGGTTAGATATGCTTTGGAAAATGGCACAACAGATAATGTAACGGTCATGGTTGTCTTC CTCTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues281
Protein Molecular Weight31549.28
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein phosphatase 2C homolog 1 MSNHSEILERPETPYDITYRVGVAENKNSKFRRTMEDVHTYVKNFASRLDWGYFAVFDGH AGIQASKWCGKHLHTIIEQNILADETRDVRDVLNDSFLAIDEEINTKLVGNSGCTAAVCV LRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVE QAGGLIMKSRVNGMLAVTRSLGDKFFDSLVVGSPFTTSVEITSEDKFLILACDGLWDVID DQDACELIKDITEPNEAAKVLVRYALENGTTDNVTVMVVFL
References
External Links
ResourceLink
Saccharomyces Genome Database PTC1
Uniprot IDP35182
Uniprot NamePTC1
General ReferenceNot Available