Protein STE5 (P32917)

Identification
NameProtein STE5
SynonymsNot Available
Gene NameSTE5
Enzyme ClassNot Available
Biological Properties
General Functionregulation of transposition, RNA-mediated
Specific FunctionComponent of the pheromone signal transduction pathway. It mediates pheromone signals acting between STE20 and STE11. It is absolutely required for pheromone-induced transcription of FUS1. May play a role in cell-cycle arrest in response to pheromone.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
cytoplasm
mating projection tip
invasive growth in response to glucose limitation
regulation of transposition, RNA-mediated
MAP-kinase scaffold activity
plasma membrane
negative regulation of MAPK cascade
phosphatidylinositol-4,5-bisphosphate binding
positive regulation of protein phosphorylation
pheromone-dependent signal transduction involved in conjugation with cellular fusion
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2754 bp ATGATGGAAACTCCTACAGACAATATAGTTTCCCCTTTTCACAATTTTGGTAGCTCGACA CAATATAGTGGTACCTTGTCGAGAACTCCCAACCAAATAATAGAGCTAGAGAAGCCCAGT ACTCTATCCCCATTGTCAAGAGGAAAAAAATGGACGGAAAAGTTAGCCAGGTTCCAAAGA AGTAGTGCTAAAAAGAAAAGATTCTCACCTTCTCCTATTTCCTCCTCTACATTTTCGTTC TCACCCAAATCTAGGGTCACTTCTTCAAACTCTTCTGGCAATGAAGACGGTAACCTAATG AATACACCTTCTACGGTTTCCACTGATTATTTGCCACAACACCCTCACAGAACATCGTCT TTGCCAAGACCTAATTCCAATCTCTTTCACGCAAGTAATAGTAACCTATCCCGAGCAAAT GAGCCCCCAAGGGCCGAAAATTTATCAGATAATATACCACCCAAGGTCGCTCCATTTGGC TATCCAATACAAAGAACCTCTATTAAAAAATCCTTTTTGAATGCTTCTTGTACGTTATGT GACGAGCCTATTTCTAACAGAAGAAAGGGAGAGAAAATTATAGAGCTTGCATGTGGCCAC TTAAGTCACCAAGAATGTCTTATTATCTCTTTTGGCACCACTTCAAAGGCAGACGTTCGT GCGCTATTTCCTTTTTGTACCAAATGTAAAAAAGATACTAACAAAGCCGTTCAATGCATT CCAGAAAATGATGAACTAAAGGATATTCTAATTTCTGATTTTTTGATTCATAAGATTCCT GATTCTGAGTTATCAATCACACCTCAGTCCCGCTTTCCTCCTTATTCACCACTCTTGCCT CCTTTTGGGTTATCCTATACACCTGTTGAAAGACAAACGATATATTCTCAAGCTCCAAGT CTAAACCCAAATCTCATATTGGCTGCACCCCCCAAGGAAAGAAACCAAATTCCACAAAAA AAATCAAACTATACATTTTTACATTCACCCCTGGGGCACAGAAGAATTCCGTCCGGAGCA AACTCTATCTTAGCAGACACCTCTGTAGCGTTGTCAGCTAATGATTCTATTTCTGCTGTT TCCAATTCGGTAAGAGCAAAGGATGACGAAACCAAAACAACGTTGCCGCTGTTAAGGTCA TATTTTATTCAAATTCTTTTGAACAATTTCCAGGAAGAATTGCAGGATTGGAGAATAGAC GGGGACTATGGATTACTAAGGTTGGTAGACAAATTGATGATTTCCAAAGATGGTCAGAGA TATATACAATGCTGGTGTTTCTTATTTGAAGACGCATTTGTAATAGCAGAAGTGGATAAC GATGTTGATGTTTTGGAAATTAGACTAAAGAATTTAGAAGTATTTACACCTATTGCCAAC TTGAGAATGACTACACTCGAAGCTTCAGTACTCAAATGCACCTTAAATAAACAACATTGC GCCGATTTATCAGATCTTTACATTGTTCAGAATATAAATTCTGACGAAAGCACAACTGTA CAGAAATGGATATCAGGTATATTGAATCAGGATTTTGTATTCAATGAGGACAATATCACT TCGACCCTGCCTATTCTTCCCATTATAAAGAACTTTTCAAAAGATGTTGGTAATGGTAGG CACGAGACGAGTACCTTTCTAGGTTTAATCAATCCTAACAAAGTTGTTGAAGTTGGAAAT GTGCACGATAATGATACTGTAATCATAAGGAGGGGATTCACCTTAAATTCAGGAGAATGT TCTAGGCAGAGTACTGTCGACAGTATACAATCTGTTCTAACCACGATAAGCTCAATTCTT TCCCTTAAACGAGAAAAACCTGATAATTTGGCAATAATCTTACAGATCGATTTTACGAAA TTGAAGGAAGAAGACAGTTTAATTGTTGTTTATAACAGTCTAAAAGCTTTAACCATTAAA TTTGCGCGTTTGCAGTTTTGTTTCGTTGATCGAAATAATTATGTTCTGGACTATGGATCG GTATTACACAAGATAGATTCACTAGATTCCATCTCAAATCTCAAATCAAAGAGTTCCTCG ACACAATTTTCACCTATTTGGTTGAAAAATACTCTATATCCCGAAAATATTCATGAACAT TTGGGTATTGTTGCTGTATCAAATAGTAATATGGAAGCAAAAAAATCCATACTATTTCAA GATTACAGATGCTTTACAAGTTTTGGAAGAAGAAGGCCCAATGAATTGAAGATTAAGGTG GGCTATTTGAACGTTGACTACAGTGATAAAATTGATGAACTAGTCGAGGCCAGCTCCTGG ACTTTTGTTTTAGAAACTCTTTGCTACAGTTTCGGTCTAAGTTTTGATGAACATGATGAC GATGACGAAGAGGATAATGATGATTCGACCGATAATGAACTTGATAATAGTTCAGGATCA CTGTCGGATGCTGAATCTACAACTACTATTCATATTGATTCTCCATTTGATAATGAAAAT GCTACCGCAAATATGGTGAATGACAGAAACCTTCTCACTGAGGGTGAACATAGCAATATA GAAAACTTAGAAACTGTCGCTTCTTCAGTACAGCCAGCTCTGATTCCTAATATTAGATTT TCACTTCATTCTGAGGAGGAAGGTACTAATGAAAATGAAAATGAAAATGATATGCCAGTA TTATTACTTAGTGATATGGATAAAGGAATCGATGGCATAACCAGACGCAGTTCATTCTCG AGTCTTATAGAGAGCGGTAATAACAACTGTCCCCTCCATATGGATTATATATAG
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues917
Protein Molecular Weight102726.09
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein STE5 MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSPLSRGKKWTEKLARFQR SSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNTPSTVSTDYLPQHPHRTSS LPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFGYPIQRTSIKKSFLNASCTLC DEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKADVRALFPFCTKCKKDTNKAVQCI PENDELKDILISDFLIHKIPDSELSITPQSRFPPYSPLLPPFGLSYTPVERQTIYSQAPS LNPNLILAAPPKERNQIPQKKSNYTFLHSPLGHRRIPSGANSILADTSVALSANDSISAV SNSVRAKDDETKTTLPLLRSYFIQILLNNFQEELQDWRIDGDYGLLRLVDKLMISKDGQR YIQCWCFLFEDAFVIAEVDNDVDVLEIRLKNLEVFTPIANLRMTTLEASVLKCTLNKQHC ADLSDLYIVQNINSDESTTVQKWISGILNQDFVFNEDNITSTLPILPIIKNFSKDVGNGR HETSTFLGLINPNKVVEVGNVHDNDTVIIRRGFTLNSGECSRQSTVDSIQSVLTTISSIL SLKREKPDNLAIILQIDFTKLKEEDSLIVVYNSLKALTIKFARLQFCFVDRNNYVLDYGS VLHKIDSLDSISNLKSKSSSTQFSPIWLKNTLYPENIHEHLGIVAVSNSNMEAKKSILFQ DYRCFTSFGRRRPNELKIKVGYLNVDYSDKIDELVEASSWTFVLETLCYSFGLSFDEHDD DDEEDNDDSTDNELDNSSGSLSDAESTTTIHIDSPFDNENATANMVNDRNLLTEGEHSNI ENLETVASSVQPALIPNIRFSLHSEEEGTNENENENDMPVLLLSDMDKGIDGITRRSSFS SLIESGNNNCPLHMDYI
References
External Links
ResourceLink
Saccharomyces Genome Database STE5
Uniprot IDP32917
Uniprot NameSTE5
PDB ID
2KGN
General ReferenceNot Available