Protein STE5 (P32917)

Identification
NameProtein STE5
SynonymsNot Available
Gene NameSTE5
Enzyme ClassNot Available
Biological Properties
General Functionregulation of transposition, RNA-mediated
Specific FunctionComponent of the pheromone signal transduction pathway. It mediates pheromone signals acting between STE20 and STE11. It is absolutely required for pheromone-induced transcription of FUS1. May play a role in cell-cycle arrest in response to pheromone.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
pheromone-dependent signal transduction involved in conjugation with cellular fusion
nucleus
cytoplasm
mating projection tip
invasive growth in response to glucose limitation
regulation of transposition, RNA-mediated
MAP-kinase scaffold activity
plasma membrane
negative regulation of MAPK cascade
phosphatidylinositol-4,5-bisphosphate binding
positive regulation of protein phosphorylation
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2754 bp ATGATGGAAACTCCTACAGACAATATAGTTTCCCCTTTTCACAATTTTGGTAGCTCGACA CAATATAGTGGTACCTTGTCGAGAACTCCCAACCAAATAATAGAGCTAGAGAAGCCCAGT ACTCTATCCCCATTGTCAAGAGGAAAAAAATGGACGGAAAAGTTAGCCAGGTTCCAAAGA AGTAGTGCTAAAAAGAAAAGATTCTCACCTTCTCCTATTTCCTCCTCTACATTTTCGTTC TCACCCAAATCTAGGGTCACTTCTTCAAACTCTTCTGGCAATGAAGACGGTAACCTAATG AATACACCTTCTACGGTTTCCACTGATTATTTGCCACAACACCCTCACAGAACATCGTCT TTGCCAAGACCTAATTCCAATCTCTTTCACGCAAGTAATAGTAACCTATCCCGAGCAAAT GAGCCCCCAAGGGCCGAAAATTTATCAGATAATATACCACCCAAGGTCGCTCCATTTGGC TATCCAATACAAAGAACCTCTATTAAAAAATCCTTTTTGAATGCTTCTTGTACGTTATGT GACGAGCCTATTTCTAACAGAAGAAAGGGAGAGAAAATTATAGAGCTTGCATGTGGCCAC TTAAGTCACCAAGAATGTCTTATTATCTCTTTTGGCACCACTTCAAAGGCAGACGTTCGT GCGCTATTTCCTTTTTGTACCAAATGTAAAAAAGATACTAACAAAGCCGTTCAATGCATT CCAGAAAATGATGAACTAAAGGATATTCTAATTTCTGATTTTTTGATTCATAAGATTCCT GATTCTGAGTTATCAATCACACCTCAGTCCCGCTTTCCTCCTTATTCACCACTCTTGCCT CCTTTTGGGTTATCCTATACACCTGTTGAAAGACAAACGATATATTCTCAAGCTCCAAGT CTAAACCCAAATCTCATATTGGCTGCACCCCCCAAGGAAAGAAACCAAATTCCACAAAAA AAATCAAACTATACATTTTTACATTCACCCCTGGGGCACAGAAGAATTCCGTCCGGAGCA AACTCTATCTTAGCAGACACCTCTGTAGCGTTGTCAGCTAATGATTCTATTTCTGCTGTT TCCAATTCGGTAAGAGCAAAGGATGACGAAACCAAAACAACGTTGCCGCTGTTAAGGTCA TATTTTATTCAAATTCTTTTGAACAATTTCCAGGAAGAATTGCAGGATTGGAGAATAGAC GGGGACTATGGATTACTAAGGTTGGTAGACAAATTGATGATTTCCAAAGATGGTCAGAGA TATATACAATGCTGGTGTTTCTTATTTGAAGACGCATTTGTAATAGCAGAAGTGGATAAC GATGTTGATGTTTTGGAAATTAGACTAAAGAATTTAGAAGTATTTACACCTATTGCCAAC TTGAGAATGACTACACTCGAAGCTTCAGTACTCAAATGCACCTTAAATAAACAACATTGC GCCGATTTATCAGATCTTTACATTGTTCAGAATATAAATTCTGACGAAAGCACAACTGTA CAGAAATGGATATCAGGTATATTGAATCAGGATTTTGTATTCAATGAGGACAATATCACT TCGACCCTGCCTATTCTTCCCATTATAAAGAACTTTTCAAAAGATGTTGGTAATGGTAGG CACGAGACGAGTACCTTTCTAGGTTTAATCAATCCTAACAAAGTTGTTGAAGTTGGAAAT GTGCACGATAATGATACTGTAATCATAAGGAGGGGATTCACCTTAAATTCAGGAGAATGT TCTAGGCAGAGTACTGTCGACAGTATACAATCTGTTCTAACCACGATAAGCTCAATTCTT TCCCTTAAACGAGAAAAACCTGATAATTTGGCAATAATCTTACAGATCGATTTTACGAAA TTGAAGGAAGAAGACAGTTTAATTGTTGTTTATAACAGTCTAAAAGCTTTAACCATTAAA TTTGCGCGTTTGCAGTTTTGTTTCGTTGATCGAAATAATTATGTTCTGGACTATGGATCG GTATTACACAAGATAGATTCACTAGATTCCATCTCAAATCTCAAATCAAAGAGTTCCTCG ACACAATTTTCACCTATTTGGTTGAAAAATACTCTATATCCCGAAAATATTCATGAACAT TTGGGTATTGTTGCTGTATCAAATAGTAATATGGAAGCAAAAAAATCCATACTATTTCAA GATTACAGATGCTTTACAAGTTTTGGAAGAAGAAGGCCCAATGAATTGAAGATTAAGGTG GGCTATTTGAACGTTGACTACAGTGATAAAATTGATGAACTAGTCGAGGCCAGCTCCTGG ACTTTTGTTTTAGAAACTCTTTGCTACAGTTTCGGTCTAAGTTTTGATGAACATGATGAC GATGACGAAGAGGATAATGATGATTCGACCGATAATGAACTTGATAATAGTTCAGGATCA CTGTCGGATGCTGAATCTACAACTACTATTCATATTGATTCTCCATTTGATAATGAAAAT GCTACCGCAAATATGGTGAATGACAGAAACCTTCTCACTGAGGGTGAACATAGCAATATA GAAAACTTAGAAACTGTCGCTTCTTCAGTACAGCCAGCTCTGATTCCTAATATTAGATTT TCACTTCATTCTGAGGAGGAAGGTACTAATGAAAATGAAAATGAAAATGATATGCCAGTA TTATTACTTAGTGATATGGATAAAGGAATCGATGGCATAACCAGACGCAGTTCATTCTCG AGTCTTATAGAGAGCGGTAATAACAACTGTCCCCTCCATATGGATTATATATAG
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues917
Protein Molecular Weight102726.09
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein STE5 MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSPLSRGKKWTEKLARFQR SSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNTPSTVSTDYLPQHPHRTSS LPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFGYPIQRTSIKKSFLNASCTLC DEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKADVRALFPFCTKCKKDTNKAVQCI PENDELKDILISDFLIHKIPDSELSITPQSRFPPYSPLLPPFGLSYTPVERQTIYSQAPS LNPNLILAAPPKERNQIPQKKSNYTFLHSPLGHRRIPSGANSILADTSVALSANDSISAV SNSVRAKDDETKTTLPLLRSYFIQILLNNFQEELQDWRIDGDYGLLRLVDKLMISKDGQR YIQCWCFLFEDAFVIAEVDNDVDVLEIRLKNLEVFTPIANLRMTTLEASVLKCTLNKQHC ADLSDLYIVQNINSDESTTVQKWISGILNQDFVFNEDNITSTLPILPIIKNFSKDVGNGR HETSTFLGLINPNKVVEVGNVHDNDTVIIRRGFTLNSGECSRQSTVDSIQSVLTTISSIL SLKREKPDNLAIILQIDFTKLKEEDSLIVVYNSLKALTIKFARLQFCFVDRNNYVLDYGS VLHKIDSLDSISNLKSKSSSTQFSPIWLKNTLYPENIHEHLGIVAVSNSNMEAKKSILFQ DYRCFTSFGRRRPNELKIKVGYLNVDYSDKIDELVEASSWTFVLETLCYSFGLSFDEHDD DDEEDNDDSTDNELDNSSGSLSDAESTTTIHIDSPFDNENATANMVNDRNLLTEGEHSNI ENLETVASSVQPALIPNIRFSLHSEEEGTNENENENDMPVLLLSDMDKGIDGITRRSSFS SLIESGNNNCPLHMDYI
References
External Links
ResourceLink
Saccharomyces Genome Database STE5
Uniprot IDP32917
Uniprot NameSTE5
PDB ID
2KGN
General ReferenceNot Available