| Identification |
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| Name | MAP kinase kinase MKK2/SSP33 |
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| Synonyms | Not Available |
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| Gene Name | MKK2 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | signal transduction |
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| Specific Function | Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth. This pathway seems to start by SMP3; then involves the kinase PKC1 that may act on the BCK1 kinase that then phosphorylates MKK1 and MKK2 which themselves phosphorylate the MPK1 kinase. |
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| Cellular Location | Not Available |
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| SMPDB Pathways | | Stress-activated signalling pathways: cell wall stress test 1 | PW007861 |    |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | |
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| GO Classification | | Function |
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| cellular bud neck | | cytoplasm | | cellular bud tip | | mating projection tip | | regulation of fungal-type cell wall organization | | MAP kinase kinase activity | | receptor signaling protein serine/threonine kinase activity | | protein phosphorylation | | protein tyrosine kinase activity | | signal transduction | | pexophagy | | ATP binding |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | |
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| Gene Sequence | >1521 bp
ATGGCTTCAATGTTCAGACCACCAGAATCCAATAGGAGTCACCAAAAGACTCCAAAATTA
ACGCTTCCAGTAAATTTAGTTCAAAATGCGAAATCCACTAATGATGGGCAACATCTCAAC
CGGTCACCGTACTCGTCAGTGAACGAAAGCCCATACTCCAACAATAGCACTTCAGCTACT
TCCACTACGTCATCCATGGCTTCAAATTCCACTTTGTTGTACAATAGATCATCTACTACA
ACTATTAAAAATAGACCGGTACCACCTCCATTACCTCCCCTAGTACTAACGCAAAAAAAA
GACGGTATAGAATATAGAGTTGCCGGCGATAGTCAGCTTTCTGAAAGATTTTCTAATTTG
CATGTTGATATAACTTACAAGGAACTACTATCTAGTGCTCCAATTTCCACTAAGTTATCC
AACATAGATACCACTTTTATCAAGAAAGATCTCGACACACCAGAAGGCGAGGATTCATAC
CCCTCGACACTTCTTTCTGCGTACGACTTCAGCAGTAGCGGGAGCAACTCCGCCCCTTTA
AGTGCAAATAACATAATTTCTTGTTCCAACTTAATACAAGGAAAAGACGTAGACCAGTTA
GAGGAAGAAGCATGGAGGTTTGGGCATCTCAAGGATGAGATTACTACACTAGGAATTCTA
GGAGAAGGCGCGGGTGGTTCTGTAGCCAAGTGCCGATTAAAAAATGGAAAAAAGGTTTTT
GCGTTGAAGACAATCAACACTATGAATACTGACCCAGAATATCAAAAGCAAATATTCAGA
GAGCTACAATTTAATAAGAGTTTTAAGTCCGATTATATTGTGCAGTACTATGGTATGTTT
ACCGACGAACAGAGTTCTTCAATATACATTGCCATGGAATATATGGGAGGAAAATCACTG
GAGGCAACGTATAAAAATTTGTTGAAACGTGGCGGTAGAATAAGTGAGAGGGTGATAGGA
AAGATAGCAGAATCTGTCTTAAGAGGTTTATCATACTTACACGAAAGGAAAGTCATCCAC
AGGGACATTAAACCCCAAAACATTCTTCTTAATGAAAAAGGGGAAATCAAATTATGCGAT
TTCGGTGTCAGTGGGGAGGCTGTTAACTCTTTAGCGATGACATTTACTGGAACGTCATTT
TATATGGCCCCAGAACGAATACAAGGCCAACCATACAGCGTAACCTGTGATGTATGGTCC
TTAGGATTAACTCTTCTGGAGGTTGCTGGAGGGAGATTTCCATTTGAATCTGACAAAATA
ACGCAAAACGTGGCTCCTATAGAATTATTGACGATGATCCTGACGTTTTCTCCCCAGTTG
AAAGATGAGCCAGAACTAGACATATCCTGGAGCAAGACATTTAGATCTTTTATCGACTAT
TGTTTAAAAAAAGATGCCAGAGAGAGGCCTTCTCCCAGGCAAATGTTAAAGCATCCCTGG
ATTGTAGGGCAAATGAAAAAAAAAGTCAACATGGAACGGTTTGTAAAGAAATGCTGGGAA
AAGGAAAAGGATGGGATATAA |
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| Protein Properties |
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| Pfam Domain Function | Not Available |
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| Protein Residues | 506 |
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| Protein Molecular Weight | 56757.035 |
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| Protein Theoretical pI | Not Available |
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| Signalling Regions | Not Available |
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| Transmembrane Regions | Not Available |
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| Protein Sequence | >MAP kinase kinase MKK2/SSP33
MASMFRPPESNRSHQKTPKLTLPVNLVQNAKSTNDGQHLNRSPYSSVNESPYSNNSTSAT
STTSSMASNSTLLYNRSSTTTIKNRPVPPPLPPLVLTQKKDGIEYRVAGDSQLSERFSNL
HVDITYKELLSSAPISTKLSNIDTTFIKKDLDTPEGEDSYPSTLLSAYDFSSSGSNSAPL
SANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLGILGEGAGGSVAKCRLKNGKKVF
ALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSL
EATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCD
FGVSGEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKI
TQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPW
IVGQMKKKVNMERFVKKCWEKEKDGI |
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| References |
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| External Links | | Resource | Link |
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| Saccharomyces Genome Database | MKK2 | | Uniprot ID | P32491 | | Uniprot Name | MKK2 |
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| General Reference | Not Available |
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