Syntaxin-8 (P31377)

Identification
NameSyntaxin-8
Synonyms
  • SNARE protein related to mammalian syntaxin 8
  • ULP1-interacting protein 2
Gene NameSYN8
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in SNAP receptor activity
Specific Functiont-SNARE which may play a role in determining the specificity of membrane fusion, protein transport and vesicle trafficking within the Golgi/endosomal and plasma membrane/endosomal systems
Cellular LocationEndosome membrane; Single-pass type IV membrane protein
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO ClassificationNot Available
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>768 bp ATGGATGTGTTGAAGCTGGGTTATGAACTGGACCAGCTCTCTGATCTGGTCGAAGAAAGA ACAAGGCTAGTGTCGGTGTTGAAGCTCGCCCCGACCTCAAACGATAACGTTACTTTGAAA CGGCAATTGGGCTCAATATTGGAGTTATTGCAGAAGTGTGCGCCCAATGATGAACTAATA TCCCGATACAATACCATACTGGACAAAATTCCTGATACGGCGGTTGACAAGGAGTTGTAT AGGTTCCAACAGCAGGTGGCAAGAAATACTGATGAGGTGTCCAAAGAGTCTTTGAAAAAA GTGCGGTTCAAGAATGATGACGAGCTTACGGTCATGTATAAGGATGACGATGAACAAGAC GAGGAGTCGCCGCTGCCTTCGACGCATACTCCATACAAGGATGAACCATTGCAATCGCAG TTACAGTCACAGTCACAGCCACAGCCACCACAACCCATGGTTTCCAACCAAGAACTATTT ATTAACCAGCAACAGCAGTTGTTAGAGCAAGATTCCCACTTGGGCGCACTGTCTCAGTCT ATTGGGAGGACTCATGACATTTCGCTGGACCTTAATAATGAGATCGTTTCTCAGAACGAC TCGCTGCTGGTTGATTTAGAAAACCTGATTGATAATAATGGTAGGAATTTGAACAGGGCC TCTCGGTCCATGCATGGCTTTAACAATTCTAGGTTCAAGGATAACGGCAACTGCGTGATT ATTCTTGTGCTGATAGTGGTGCTCCTGTTGCTTCTATTAGTATTATAA
Protein Properties
Pfam Domain Function
Protein Residues255
Protein Molecular Weight29048.5
Protein Theoretical pI4.42
Signalling Regions
  • None
Transmembrane Regions
  • 235-255
Protein Sequence>Syntaxin-8 MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLGSILELLQKCAPNDELI SRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVRFKNDDELTVMYKDDDEQD EESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELFINQQQQLLEQDSHLGALSQS IGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLNRASRSMHGFNNSRFKDNGNCVI ILVLIVVLLLLLLVL
References
External Links
ResourceLink
Saccharomyces Genome Database SYN8
Uniprot IDP31377
Uniprot NameSTX8_YEAST
GenBank Gene IDAY205236
Genebank Protein ID27803596
General Reference
  • Lewis, M. J., Pelham, H. R. (2002). "A new yeast endosomal SNARE related to mammalian syntaxin 8." Traffic 3:922-929.12453154
  • Ouellette, B. F., Clark, M. W., Keng, T., Storms, R. K., Zhong, W., Zeng, B., Fortin, N., Delaney, S., Barton, A., Kaback, D. B., et, a. l. .. (1993). "Sequencing of chromosome I from Saccharomyces cerevisiae: analysis of a 32 kb region between the LTE1 and SPO7 genes." Genome 36:32-42.8458570
  • Barton, A. B., Kaback, D. B. (1994). "Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUN38-MAK16-SPO7 region." J Bacteriol 176:1872-1880.8144453
  • Bussey, H., Kaback, D. B., Zhong, W., Vo, D. T., Clark, M. W., Fortin, N., Hall, J., Ouellette, B. F., Keng, T., Barton, A. B., et, a. l. .. (1995). "The nucleotide sequence of chromosome I from Saccharomyces cerevisiae." Proc Natl Acad Sci U S A 92:3809-3813.7731988
  • Valdez-Taubas, J., Pelham, H. (2005). "Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation." EMBO J 24:2524-2532.15973437
  • Roth, A. F., Wan, J., Bailey, A. O., Sun, B., Kuchar, J. A., Green, W. N., Phinney, B. S., Yates, J. R. 3rd, Davis, N. G. (2006). "Global analysis of protein palmitoylation in yeast." Cell 125:1003-1013.16751107