Serine/threonine-protein kinase SSK22 (P25390)

Identification
NameSerine/threonine-protein kinase SSK22
Synonyms
  • MAP kinase kinase kinase SSK22
  • Suppressor of sensor kinase 22
Gene NameSSK22
Enzyme ClassNot Available
Biological Properties
General Functionstress-activated MAPK cascade
Specific FunctionKinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the PBS2 MAP kinase kinase by phosphorylation.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarityPW002516 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity 1469654356PW002970 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
ATP binding
cytoplasm
receptor signaling protein serine/threonine kinase activity
MAP kinase kinase kinase activity
MAPK cascade involved in osmosensory signaling pathway
stress-activated MAPK cascade
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>3996 bp ATGATGATGGATATACTGAATACACAGCAACAAAAAGCGGCTGAAGGCGGGAGAGTTCTG GCTCCTCATACCATCTCAAGTAAGCTCGTGAAGAGATTATCAAGTCATTCCAGCCATAAA CTATCAAGATCTGATTTGAAAGCATTGGGTGGCTCGGAAACAATAAGCGACGGCCCCAGT CAGCTGACTTTTAAGGACCGATACGTTTTCAATGAATCGCTATACTTGAAAAAGCTAAAA AAGACCGCTTTAGATGACTACTACACGAGGGGCATAAAACTCACTAACCGCTACGAGGAA GACGACGGTGATGACGAAATTATTCGGTTGTCTAATGGCGACAGAATTGATGAAGACCTG CACTCAGGTGTCAAGTTTTTCTCCACTACACCTTATTGCAGGAAAATGAGGTCAGACAGT GATGAACTAGCTTGGAATGAAATTGCGACCGAACGGTTCAAATGGCAGTCAATGCTGGCC AGAGTGCTGAAGGGAGATATTGTTAAAGGTGAAAAGACGAGGATTGCTAACCAAGTCAAG AAACCAGGGTTAAATAAGGAGCTCTCAGATGAGATATGGCTCGAATTGAAGGCATGGCTG AATGGGAGGACCATGCAAGAGATGGAACAGTCGCTTACATATTTAAGAGATAGTTCAGAT TCCGTTTTTGAAGAGATAATGAAGTTTCAAATTCCACAGGGCAAGATATTGAGCCTGGAT GCACTGGAGGCCATCTTACAAGACCTCATGAACAGATATCACAGCGTTGTCTCTTATTGG CCTAACTTGAAAAAAATGTATAAGGATAAACCAATCACCAATACTGCAGAATTTACCGCT AGAATAGACGTAATGAATTCTTGGCTGAACTTTAAAACGAACTTAACGTTGAGGAGGCAA GAGTTGGACGACTGGATAAACCGTTTCTCACCGATAAGTAGTTCGGATAATTGCCAAGAG GATTTTGATGGTGTGCCCCAATGGAACTGCAAAATGAAGATTCTTGCAGAACAATTGATG AAGGAAAAGAACATCGAGTCTATATTCCAAAAAAAAATTTTCTATCCGCTATCACCTTGG ATGTTCAAACTGAAACTACATTTTATAGTCTACAGAGAAACTTTGACAAAGATGAACATA AAATATCCTTATGAAAGGTTAAGATCACTACTGGCGTTCCCCGTCTATTTAATCAAAGAA GTTATTTTGACTAGATTGTCATATGCACGAAAGCTTAAAAATCCAACAATGATGATGATC GATCAAATGATCGATGATTTTAACGCTTTTATTCGACTTTCTGTGCAATTGAAGTACACA CTGACAAAATATTGCTCCAATTTGCCGTTCGATGTGGATTTTGACCCGACGTTCGAAAAT ACTGTAATAGAAGCCATTCGTTATTTATTTTTTCTGTTGAATTTAAAGTTGATTGATTCC AGTAAACAAAATTTCAAAGCACCCGATCTACTCTTGAAATACTGGGATCACCTAAAAAAC ACCGGTCACTATATTAACGGTGCAGAAACCGTGATTCCAAATGAATTTCTCAAGTTAACT TTGAGACTCGTACATAAATTGCAATTCTATCTTTTGAAACAACAAAACTTCCCACCAACA TTTGCTAACGCTTCAGAAGCAGAAAAATGGCTAAGTTCCATTTTCGAAAATTTGGGTGCC ATGAAAAGAAAGCTGAACAGGTTCAGCAATATTCTAGTCAAGGCGTTCCAAAATTCTGCT GTTTATCAGATTAATCATAATGCACAACTTGTTAAAAAGTTAAAAGATGCTCACTATTTT TTGGTATACTCCGGTAACACTTTTGAGTCTAGTGGTGTATATATGTTTGCTGCTCCTGAA TTATTAGGTTGTGACAATGATACCATCTTAAGAATTTTGCGAAATAAATCCATTGGCTGT GATTTGGTCCCAAAGCTTGACATTGGAAATAATTTGAATGTGTATGATATAACAACAAAA GAAACAGATTTGAACATTCTAGTATCGAAAGGGGAGGATTCCAAAGGAATTCCTTACTAC CGAGTAGTAGCAAATTCGTCAAGTGATTTGGACAGGCATGCTCATCAGTCCAAAAAGAAG AATTTTTCAACAGACCCTTTTGATCAGCACCTTGATGAAAAGAACAATGAAGTTTTTGAA TTGGAAGTTGCTTTGAGCTCATTGGGTGCACTAGTTGTACTATATCCTGGAGAGCCAGTA GTTTGGGATGGACCAGTATATAAGCTTCCAGGTAACAACCTTTTTGCATCCAACGAAATG GATTTAGGGAAAATTGGTAACCCAAATACGTTGATTTTACTCAATCAAGGTTCTAATTAT GCACTGACTTATCAAATCGACAAGTTTAATCAAACGGTAGGTGATTCTGTTTCATTCATA GAGAAACGTTGTTCACTCAATTCAATTGAATCCTCCCTACAAAAAATCAATAAGGCATAT TACAAACTTACTTATACAGTATTGAACAACTACAAAGGAATTCTAGGTAGCTTTATGAAG CAATGTCCGGGAAATGAGTTGTTAAATTCGATATTCATGTTTGGAAGGGATTTTGGAAGA AGTTTCCTTAAATATAACGCCTTTAGCTCAAAGAGGAAGTACGTTATCATCTTTCTGATG GTTAAATTAGGAATGAACTGGTTGAAATTCCTTGTTGAAGAGTGTGATCCTACCGATCAG CGAACTTTCCGATGGTGCGTTCTTGCAATGGATTTTGCGATGCAGATGACTAGTGGTTAT AATATCCTGGCGCTGAATGTAAAGCAATTTCAAGAACTGAAGGAGAGGGTATCAGTATGT ATGTCATTATTAATTTCACATTTCGACGTTATGGGTGCACGAGCCACTGAAGCTGAAAAT GGCATGCAACAGGCAAGATTGAATATTGATACTGAAGAGAATATTGATGAAGAGGCCACC CTAGAAATAAACAGCAGGTTGAGACTGGAAGCTATAAAGACGTTGGAAAAGACTATGAAG AGGAATCCCAGGCAAATGGGTAAGGTATTGGATGCTACAGATCAGGGAAACAAATACCTA CTATCGCTAGCATCCTCATTATCGAATGTATCAATGAGGTGGCAAAAAAGAAGCTTCATT GGCGGTGGAACATTTGGACAGGTATACTCTGCAATTAATCTGGAAAACGGTGAAATCTTA GCTGTTAAGGAAATAAAGATACACGATACCACAACAATGAAGAAGATTTTTCCCCTGATT AAAGAAGAGATGACCGTATTGGAAATGTTAAACCATCCTAATATTGTCCAGTACTATGGT GTCGAAGTACATCGCGATAAAGTTAACATCTTCATGGAATACTGTGAGGGTGGTTCTTTA GCCTCGTTATTGGATCATGGAAGAATTGAAGATGAAATGGTAACACAAGTGTACACATTC GAACTATTAGAAGGTTTGGCATATTTGCACCAATCTGGCGTGGTGCATCGCGACATTAAA CCGGAGAATATCTTGCTGGATTTCAATGGAATCATAAAATATGTGGATTTTGGTACGGCA CGTACCGTTGTAGGATCTAGGACTAGAACTGTGCGGAACGCAGCCGTTCAAGATTTTGGA GTAGAAACAAAGTCCCTCAATGAAATGATGGGGACACCGATGTATATGGCTCCAGAGACT ATTTCAGGCTCGGCAGTTAAGGGAAAACTTGGAGCGGACGATGTATGGGCATTAGGATGT GTTGTGCTAGAAATGGCCACAGGTAGACGACCTTGGTCTAACTTGGATAATGAATGGGCC ATCATGTACCACGTTGCTGCAGGTCGAATACCGCAACTACCCAATAGAGACGAAATGACT GCAGCGGGAAGAGCCTTCTTGGAAAGGTGTTTGGTTCAAGACCCCACTATGAGGGCTACT GCTGTGGAACTACTGATAGACCCTTGGATGATACAAATCCGTGAAATAGCATTTGGCAAC TCAGAGAAAGATCAAGTACCTATCCTAAGCTCATAG
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1331
Protein Molecular Weight152716.45
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Serine/threonine-protein kinase SSK22 MMMDILNTQQQKAAEGGRVLAPHTISSKLVKRLSSHSSHKLSRSDLKALGGSETISDGPS QLTFKDRYVFNESLYLKKLKKTALDDYYTRGIKLTNRYEEDDGDDEIIRLSNGDRIDEDL HSGVKFFSTTPYCRKMRSDSDELAWNEIATERFKWQSMLARVLKGDIVKGEKTRIANQVK KPGLNKELSDEIWLELKAWLNGRTMQEMEQSLTYLRDSSDSVFEEIMKFQIPQGKILSLD ALEAILQDLMNRYHSVVSYWPNLKKMYKDKPITNTAEFTARIDVMNSWLNFKTNLTLRRQ ELDDWINRFSPISSSDNCQEDFDGVPQWNCKMKILAEQLMKEKNIESIFQKKIFYPLSPW MFKLKLHFIVYRETLTKMNIKYPYERLRSLLAFPVYLIKEVILTRLSYARKLKNPTMMMI DQMIDDFNAFIRLSVQLKYTLTKYCSNLPFDVDFDPTFENTVIEAIRYLFFLLNLKLIDS SKQNFKAPDLLLKYWDHLKNTGHYINGAETVIPNEFLKLTLRLVHKLQFYLLKQQNFPPT FANASEAEKWLSSIFENLGAMKRKLNRFSNILVKAFQNSAVYQINHNAQLVKKLKDAHYF LVYSGNTFESSGVYMFAAPELLGCDNDTILRILRNKSIGCDLVPKLDIGNNLNVYDITTK ETDLNILVSKGEDSKGIPYYRVVANSSSDLDRHAHQSKKKNFSTDPFDQHLDEKNNEVFE LEVALSSLGALVVLYPGEPVVWDGPVYKLPGNNLFASNEMDLGKIGNPNTLILLNQGSNY ALTYQIDKFNQTVGDSVSFIEKRCSLNSIESSLQKINKAYYKLTYTVLNNYKGILGSFMK QCPGNELLNSIFMFGRDFGRSFLKYNAFSSKRKYVIIFLMVKLGMNWLKFLVEECDPTDQ RTFRWCVLAMDFAMQMTSGYNILALNVKQFQELKERVSVCMSLLISHFDVMGARATEAEN GMQQARLNIDTEENIDEEATLEINSRLRLEAIKTLEKTMKRNPRQMGKVLDATDQGNKYL LSLASSLSNVSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLI KEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTF ELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFG VETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWA IMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGN SEKDQVPILSS
References
External Links
ResourceLink
Saccharomyces Genome Database SSK22
Uniprot IDP25390
Uniprot NameSSK22
General ReferenceNot Available