Regulatory protein SWI4 (P25302)

Identification
NameRegulatory protein SWI4
Synonyms
  • Cell-cycle box factor subunit SWI4
  • Protein ART1
Gene NameSWI4
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of transcription involved in G1/S transition of mitotic cell cycle
Specific FunctionPart of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB).
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
SBF transcription complex
DNA binding
positive regulation of transcription from RNA polymerase II promoter in response to heat stress
positive regulation of transcription involved in G1/S transition of mitotic cell cycle
nuclear chromatin
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
identical protein binding
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>3282 bp ATGCCATTTGATGTTTTGATATCAAACCAAAAAGATAATACCAATCACCAGAACATCACG CCAATATCAAAATCAGTTCTTTTGGCGCCTCATTCAAACCATCCAGTGATTGAAATAGCT ACGTATTCAGAAACCGATGTATACGAATGCTATATACGTGGGTTTGAAACTAAAATAGTG ATGAGAAGAACTAAAGATGATTGGATTAATATTACCCAGGTTTTCAAAATAGCTCAATTT TCGAAGACGAAAAGAACTAAAATACTGGAAAAGGAATCAAATGATATGCAACATGAAAAA GTTCAAGGTGGGTATGGTAGGTTTCAAGGTACTTGGATCCCACTGGATTCAGCGAAGTTT TTAGTCAATAAGTACGAAATAATTGACCCTGTGGTCAACTCCATCTTAACTTTTCAATTC GATCCAAATAACCCTCCACCAAAGAGAAGCAAAAATAGTATATTGAGGAAGACTTCGCCG GGAACGAAGATAACTTCTCCATCGAGCTACAATAAAACACCAAGAAAAAAGAACAGTAGT TCATCAACATCGGCTACAACTACAGCTGCGAATAAGAAAGGCAAGAAAAATGCATCGATC AACCAGCCGAATCCAAGTCCTTTACAAAACCTTGTTTTCCAAACTCCTCAACAGTTCCAA GTAAATTCATCAATGAATATAATGAACAATAATGATAACCACACCACGATGAATTTCAAC AATGACACAAGACACAATTTAATAAATAATATTAGTAACAACAGCAATCAATCTACTATT ATTCAACAACAAAAATCCATTCATGAAAACTCTTTCAATAATAATTATTCGGCAACTCAG AAACCTCTTCAATTTTTTCCAATTCCGACAAATTTACAAAACAAGAACGTTGCTCTGAAT AACCCTAATAATAATGACAGTAATAGTTACAGCCATAACATCGACAATGTCATTAACAGC AGTAATAACAATAATAATGGCAATAATAATAACTTGATCATAGTTCCAGACGGACCTATG CAAAGCCAACAACAACAACAACATCATCATGAATATTTGACGAATAACTTCAATCATTCC ATGATGGACTCCATTACAAATGGCAATAGTAAAAAAAGGAGGAAAAAGCTGAATCAATCT AATGAACAACAATTTTACAACCAGCAAGAAAAAATACAAAGGCATTTCAAATTAATGAAG CAACCCTTATTATGGCAATCCTTTCAAAATCCAAATGATCACCATAATGAGTACTGTGAC AGTAACGGCAGCAACAATAACAACAACACTGTAGCATCCAATGGCTCCTCCATTGAAGTA TTTTCATCAAATGAAAATGATAACAGTATGAATATGTCTTCACGATCTATGACACCGTTC AGCGCAGGAAATACTTCATCTCAAAACAAGTTGGAAAACAAAATGACAGATCAAGAATAC AAGCAGACGATATTAACAATACTATCATCGGAAAGGTCTTCTGATGTAGATCAAGCGTTG TTGGCTACTTTATATCCGGCGCCCAAAAATTTTAACATAAATTTTGAAATTGATGATCAA GGTCACACTCCACTCCATTGGGCTACAGCTATGGCGAATATTCCTTTGATAAAAATGCTA ATTACCTTAAATGCTAATGCATTACAGTGTAATAAGCTCGGTTTTAATTGCATCACAAAA TCAATTTTCTACAACAATTGCTACAAGGAGAATGCTTTCGATGAAATAATATCCATCTTA AAAATATGTCTTATAACTCCCGACGTAAATGGAAGATTGCCATTTCATTATTTAATTGAA TTGAGCGTTAATAAGTCCAAAAATCCAATGATAATAAAATCTTATATGGATTCGATAATA TTGAGCTTGGGTCAGCAGGACTACAATTTGTTGAAGATATGTTTGAACTACCAAGATAAT ATAGGGAACACTCCACTGCATTTATCTGCTTTAAACTTGAACTTCGAGGTTTACAACAGA CTGGTATATCTTGGTGCGTCAACAGATATATTGAATCTAGATAACGAATCGCCTGCGTCA ATAATGAATAAGTTTAATACTCCGGCTGGCGGGTCAAACAGCAGAAACAACAACACCAAG GCAGATCGAAAGTTAGCTCGAAACCTTCCTCAAAAGAATTATTACCAACAACAGCAACAG CAACAGCAACCACAAAACAATGTCAAAATTCCAAAAATTATAAAAACTCAACATCCTGAT AAAGAAGATTCTACTGCAGATGTCAATATAGCTAAAACAGATTCTGAAGTCAACGAAAGT CAATACCTGCATTCCAACCAGCCAAATTCTACAAATATGAACACTATTATGGAAGACTTG TCGAATATTAATTCTTTCGTGACGTCGTCTGTCATTAAAGATATAAAGTCTACGCCGTCC AAAATTCTTGAAAACTCTCCCATTTTATACAGAAGAAGATCACAGTCAATATCAGATGAA AAAGAAAAGGCAAAGGATAATGAGAATCAAGTTGAAAAGAAAAAGGATCCCTTGAATAGT GTGAAAACTGCCATGCCATCATTGGAATCGCCTTCTTCCCTTCTGCCGATACAGATGTCT CCACTAGGAAAGTACTCAAAACCGCTTTCGCAGCAGATCAACAAATTAAATACAAAAGTT TCTTCTCTACAAAGAATAATGGGTGAAGAAATTAAAAATCTGGACAACGAAGTAGTAGAA ACCGAATCCTCTATTTCTAACAATAAGAAGAGATTGATTACAATAGCACATCAAATAGAG GATGCTTTCGATTCCGTATCAAACAAAACTCCCATAAATTCGATATCAGATTTACAATCA AGGATTAAAGAAACATCGTCAAAGTTGAATTCTGAAAAGCAAAATTTTATTCAAAGCTTG GAAAAATCTCAAGCTTTAAAACTGGCTACAATTGTCCAGGATGAGGAATCAAAGGTTGAT ATGAATACTAACTCAAGTTCACATCCAGAAAAACAGGAAGATGAAGAGCCAATTCCAAAG TCAACGTCGGAAACTTCTTCTCCTAAAAACACCAAAGCGGACGCCAAATTTTCTAATACT GTACAAGAATCATATGATGTAAATGAGACGTTGAGACTAGCAACGGAACTAACTATTCTA CAGTTTAAAAGAAGGATGACAACATTGAAAATAAGCGAAGCTAAAAGCAAAATTAATTCA TCGGTGAAGTTAGATAAATACAGAAACTTGATTGGTATCACAATTGAGAACATTGACTCA AAATTGGACGATATAGAAAAGGATTTGAGGGCAAACGCATAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues1093
Protein Molecular Weight123805.37
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Regulatory protein SWI4 MPFDVLISNQKDNTNHQNITPISKSVLLAPHSNHPVIEIATYSETDVYECYIRGFETKIV MRRTKDDWINITQVFKIAQFSKTKRTKILEKESNDMQHEKVQGGYGRFQGTWIPLDSAKF LVNKYEIIDPVVNSILTFQFDPNNPPPKRSKNSILRKTSPGTKITSPSSYNKTPRKKNSS SSTSATTTAANKKGKKNASINQPNPSPLQNLVFQTPQQFQVNSSMNIMNNNDNHTTMNFN NDTRHNLINNISNNSNQSTIIQQQKSIHENSFNNNYSATQKPLQFFPIPTNLQNKNVALN NPNNNDSNSYSHNIDNVINSSNNNNNGNNNNLIIVPDGPMQSQQQQQHHHEYLTNNFNHS MMDSITNGNSKKRRKKLNQSNEQQFYNQQEKIQRHFKLMKQPLLWQSFQNPNDHHNEYCD SNGSNNNNNTVASNGSSIEVFSSNENDNSMNMSSRSMTPFSAGNTSSQNKLENKMTDQEY KQTILTILSSERSSDVDQALLATLYPAPKNFNINFEIDDQGHTPLHWATAMANIPLIKML ITLNANALQCNKLGFNCITKSIFYNNCYKENAFDEIISILKICLITPDVNGRLPFHYLIE LSVNKSKNPMIIKSYMDSIILSLGQQDYNLLKICLNYQDNIGNTPLHLSALNLNFEVYNR LVYLGASTDILNLDNESPASIMNKFNTPAGGSNSRNNNTKADRKLARNLPQKNYYQQQQQ QQQPQNNVKIPKIIKTQHPDKEDSTADVNIAKTDSEVNESQYLHSNQPNSTNMNTIMEDL SNINSFVTSSVIKDIKSTPSKILENSPILYRRRSQSISDEKEKAKDNENQVEKKKDPLNS VKTAMPSLESPSSLLPIQMSPLGKYSKPLSQQINKLNTKVSSLQRIMGEEIKNLDNEVVE TESSISNNKKRLITIAHQIEDAFDSVSNKTPINSISDLQSRIKETSSKLNSEKQNFIQSL EKSQALKLATIVQDEESKVDMNTNSSSHPEKQEDEEPIPKSTSETSSPKNTKADAKFSNT VQESYDVNETLRLATELTILQFKRRMTTLKISEAKSKINSSVKLDKYRNLIGITIENIDS KLDDIEKDLRANA
References
External Links
ResourceLink
Saccharomyces Genome Database SWI4
Uniprot IDP25302
Uniprot NameSWI4
General ReferenceNot Available