G2/mitotic-specific cyclin-2 (P24869)

Identification
NameG2/mitotic-specific cyclin-2
SynonymsNot Available
Gene NameCLB2
Enzyme ClassNot Available
Biological Properties
General Functionregulation of mitotic spindle elongation
Specific FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the CDC2 protein kinase to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
cellular bud neck
cytoplasm
cell division
positive regulation of spindle pole body separation
mitotic nuclear division
cyclin-dependent protein serine/threonine kinase regulator activity
regulation of cyclin-dependent protein serine/threonine kinase activity
G2/M transition of mitotic cell cycle
spindle
spindle pole body
negative regulation of protein dephosphorylation
regulation of mitotic spindle elongation
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1476 bp ATGTCCAACCCAATAGAAAACACAGAAAACTCACAGAATACTAGTTCATCAAGGTTTTTG AGGAATGTACAAAGGTTGGCCTTAAACAATGTAACAAATACGACATTTCAAAAGAGTAAT GCGAATAATCCAGCCCTAACAAATTTCAAATCTACACTAAACTCAGTAAAGAAGGAGGGA AGTCGGATTCCTCAATTTACTAGAGAAAGCGTATCAAGATCAACAGCCGCACAAGAGGAG AAAAGAACCCTGAAAGAAAATGGTATCCAACTCCCCAAAAACAATCTTTTAGATGATAAA GAAAACCAAGACCCAAGTAGTCAGCAATTTGGTGCGCTAACTTCTATAAAGGAGGGGAGA GCTGAGCTGCCTGCAAATATAAGTTTACAAGAATCCTCCTCAGCGAAGGAGATAATCCAG CATGATCCCCTAAAAGGCGTTGGATCAAGCACTGAGGTAGTCCATAACTCGGTAGAAAAC GAAAAACTTCATCCAGCTAGAAGTCAACTTCAAGTTAGAAATACCGAAAGTGAAACTGAT AGTGGAAAAAAAAGACCAATTTCTACAATTGTTGAACAAGAACTGCCCAAAAAGTTTAAA GTGTGCGATGAAAATGGCAAAGAAGAATATGAATGGGAAGACCTAGATGCAGAAGATGTA AATGATCCATTCATGGTCAGCGAGTACGTCAATGATATATTCGAATATCTCCACCAACTA GAGGTCATTACTCTTCCAAAGAAGGAAGATCTCTATCAGCATAGAAATATTCATCAAAAT CGAGATATCCTAGTTAATTGGTTGGTTAAAATCCATAATAAATTCGGCTTATTACCGGAG ACTTTGTATCTTGCCATTAACATAATGGACAGGTTTTTAGGTAAAGAGCTAGTTCAACTG GATAAGTTACAATTGGTTGGCACATCATGCCTTTTCATTGCCTCTAAATATGAAGAGGTC TATTCTCCTAGTATAAAACATTTCGCATCAGAGACAGACGGTGCATGTACGGAAGATGAA ATCAAAGAAGGGGAGAAATTCATTTTAAAGACATTGAAATTTAACCTAAATTATCCCAAT CCGATGAATTTTCTGAGAAGAATTTCGAAAGCAGATGACTACGATATACAGTCTCGAACT CTTGCCAAATTCTTATTAGAGATATCATTGGTAGATTTCAGATTTATTGGGATACTACCC TCATTGTGTGCAGCAGCTGCGATGTTTATGTCGAGAAAAATGTTAGGTAAAGGTAAATGG GATGGAAATCTAATACACTATAGCGGCGGGTATACTAAAGAAGAACTTGCGCCCGTGTGT CACATGATAATGGATTATCTAGTGAGTCCAATTGTTCATGATGAATTTCATAGAAAATAT CAATCTAGAAGATTTATGAAAGCTTCTATAATTTCCGTCCAATGGGCTTTAAAGGTTAGA AAAAACGGCTATGATATAATGACCTTGCATGAATGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues491
Protein Molecular Weight56246.34
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>G2/mitotic-specific cyclin-2 MSNPIENTENSQNTSSSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEG SRIPQFTRESVSRSTAAQEEKRTLKENGIQLPKNNLLDDKENQDPSSQQFGALTSIKEGR AELPANISLQESSSAKEIIQHDPLKGVGSSTEVVHNSVENEKLHPARSQLQVRNTESETD SGKKRPISTIVEQELPKKFKVCDENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQL EVITLPKKEDLYQHRNIHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQL DKLQLVGTSCLFIASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPN PMNFLRRISKADDYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGKGKW DGNLIHYSGGYTKEELAPVCHMIMDYLVSPIVHDEFHRKYQSRRFMKASIISVQWALKVR KNGYDIMTLHE
References
External Links
ResourceLink
Saccharomyces Genome Database CLB2
Uniprot IDP24869
Uniprot NameCLB2
General ReferenceNot Available