GTPase-activating protein SAC7 (P17121)

Identification
NameGTPase-activating protein SAC7
SynonymsNot Available
Gene NameSAC7
Enzyme ClassNot Available
Biological Properties
General Functionsignal transduction
Specific FunctionGTPase-activating protein for RHO1. Must be involved in the normal assembly or function or both of actin. Plays an essential role only at low temperatures.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
regulation of fungal-type cell wall organization
cell cortex
GTPase activator activity
signal transduction
cytoskeleton
negative regulation of protein kinase C signaling
negative regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of actin cytoskeleton organization
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1965 bp ATGCCAAATAATACTCTTAAACAAGGCTCCAAAATTGAAAATGTTTCTCCCTCTAAAGGT CATGTCCCAAGTTTTTGGAAGCAGTTCATAAACAACCCTAAGAGTATGTCATCCGAAAAT ATTACAGTCCCTAGATCACCAACTTCTCTTTCAAGGAATGCTCAACCAACTACTTTAAAA CGGCCTCCATTATCTTCAAGACCATATTCATATAATACCCCAACCAAAGATAGGAAATCC TTTTCCAAATCCGCGAAACAGAACAATAACAATAACAACGCTAATTCCGGAACATCGCCT CACGCAGAGTTCAAAAATTACAGAGATATGTTTTTATCTAATAGAAATGGTTTCACAGGT AGGGTTTTCGGTGTTACTTTAGCAGAATCGTTGAGCGTCGCCAGTGCAGAGGTCATTGTT CAAAGTGAGTTGGTGAGTTTTGGTCGGATACCCATCGTGGTAGCCAAGTGCGGCGCATAC TTAAAAGCAAATGGATTGGAGACCTCGGGTATATTTCGTATAGCGGGCAATGGTAAAAGA GTAAAAGCCCTTCAATACATATTCTCGTCGCCACCTGATTATGGTACCAAATTCAACGAT TGGGAAACATATACAGTGCACGATGTTGCATCGCTCCTGAGGAGATACCTTAATAATTTG GCCGAACCACTAATACCTTTATCCCTATATGAACAATTCAGAAACCCGCTACGATCTAGA CCAAGAATCCTAAGGCATATGTTGACCCACGAAGTTTCTCATCCGAATGCGAATAAAACA AATAATGTAACAGTAAAATCAAGTAGACAGAACTATAATGATGATGGTGCTAATGATGGT GACATCGAAAAGGAGGACGCTAAAGATGATGAAGAAAAAAGACGAAGAAAAATACGTCAT AAGAGAAGGCTGACCCGCGATATAAGGGCAGCTATCAAGGAATATGAAGAGCTCTTTGTT ACCTTATCAAATGACACGAAACAGCTAACTATATACCTACTCGATTTACTGAGTCTTTTT GCAAGGCAATCACAGTTTAACCTAATGTCTGGTAGAAACTTGGCGGCCATCTTCCAACCT TCAATATTATCGCATCCTCAACATGATATGGACCCCAAAGAATACGAGTTATCCCGACTA GTAGTGGAATTTTTGATTGAATACTCGTACAAGCTATTACCCCATCTTTTGAAGTTGGCT AAAAGGGAACAACAGGAACGGTTGTCAACCGAAAATAAGAAAAATAATGGAGATAAACAG AAAACTGATCCTATAGAAATACCAAAGATCACCTCATCGGATTCGCCACCAATAGTTTCT TCCAATAAAAACCCACCGGCGATTGACAATAACAATAAACTAGACCATACGACGTTATCG CCAATATCTACTTCGATACCGGAGAACTCATCAGACCTACAGACTTCAAAAATGTTAAAG CCTCCGAAGCAAAGAAGACCACACTCAAAATCGTTTGGTTCTACTCCGGTTCCTCCGGAT GTTATTGCTAGTAATAAAAGAAGAACGAGTTTATTCCCGTGGTTACATAAACCGGGAATT TTGAGTGACACAGGAGACAATGGCGACTTAACTGCTACTGAAGCTGAAGGTGATGATTAT GAAGAAGAAAATGTTGATCCATACGGTCAGTCTCCATCTAGCGTACACTCAGGTTCTTTG CCCAAACAGCATTATCTGCCAATTCCTCGAATGAACAGATCGTTGAGTGGAAACAGTACC AATTCGTCCTTTAACACTAGACCTATTTCAATGATCCTGACCAGTGGTAATGATAATTCC GCTGATCAATTAGAATTACTAAGTAACACTCATAGCAATAATGAGCGCAGTAATGCTTTA CCATTAACCGAAGATGATGGGGATGAAAGAAATTCAAGATCACGCAAGAGGGAATCATGG TTTCAAAGACTAACAAGCCGTTCAGGCTCTGCTAACAGGGCTTGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues654
Protein Molecular Weight73628.515
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>GTPase-activating protein SAC7 MPNNTLKQGSKIENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTSLSRNAQPTTLK RPPLSSRPYSYNTPTKDRKSFSKSAKQNNNNNNANSGTSPHAEFKNYRDMFLSNRNGFTG RVFGVTLAESLSVASAEVIVQSELVSFGRIPIVVAKCGAYLKANGLETSGIFRIAGNGKR VKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLNNLAEPLIPLSLYEQFRNPLRSR PRILRHMLTHEVSHPNANKTNNVTVKSSRQNYNDDGANDGDIEKEDAKDDEEKRRRKIRH KRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAIFQP SILSHPQHDMDPKEYELSRLVVEFLIEYSYKLLPHLLKLAKREQQERLSTENKKNNGDKQ KTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPISTSIPENSSDLQTSKMLK PPKQRRPHSKSFGSTPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLTATEAEGDDY EEENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTNSSFNTRPISMILTSGNDNS ADQLELLSNTHSNNERSNALPLTEDDGDERNSRSRKRESWFQRLTSRSGSANRA
References
External Links
ResourceLink
Saccharomyces Genome Database SAC7
Uniprot IDP17121
Uniprot NameSAC7
General ReferenceNot Available