Regulatory protein SWI6 (P09959)

Identification
NameRegulatory protein SWI6
Synonyms
  • Cell-cycle box factor subunit SWI6
  • MBF subunit P90
  • Trans-acting activator of HO endonuclease gene
Gene NameSWI6
Enzyme ClassNot Available
Biological Properties
General Functionpositive regulation of transcription involved in G1/S transition of mitotic cell cycle
Specific FunctionPart of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB).
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
nucleus
cytoplasm
positive regulation of transcription from RNA polymerase II promoter
MBF transcription complex
SBF transcription complex
DNA binding
RNA polymerase II transcription coactivator activity
positive regulation of reciprocal meiotic recombination
positive regulation of transcription from RNA polymerase II promoter in response to heat stress
positive regulation of transcription involved in G1/S transition of mitotic cell cycle
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>2412 bp ATGGCGTTGGAAGAAGTGGTACGATACTTAGGACCTCACAATGAGATCCCTTTGACACTC ACTAGAGACTCGGAGACTGGCCATTTCCTCCTGAAACATTTTCTGCCCATTTTGCAGCAA TATCATGACACGGGGAATATTAACGAGACCAACCCCGATAGTTTCCCCACTGATGAGGAA AGAAATAAATTACTGGCACATTATGGAATTGCTGTAAATACAGACGACCGAGGTGAGTTA TGGATAGAGCTGGAAAAATGTTTACAATTATTAAACATGCTAAATTTATTCGGTTTGTTC CAGGATGCATTCGAATTTGAGGAGCCTGAAACAGATCAGGATGAAGAAGATCCCAGCCAT TCGAAACTACCAGAAAACAAGACCAAAAGTGAAAATTCTAAGGATAATATCAGCTCAAAG AGGATTAATAATTTACAAGATATGAGCCTGGATTCTGATGCACACAGAGAATTAGGCTCT CCTTTAAAAAAACTAAAAATAGATACCTCTGTAATAGATGCTGAGAGTGACTCCACTCCG AATACTGCCAGAGGCAAGCCTAACGATGATATTAATAAGGGCCCTAGCGGCGACAATGAA AATAATGGCACTGATGACAATGACAGAACCGCTGGACCTATCATAACATTCACTCATGAC CTAACTTCTGACTTTTTAAGCAGTCCACTGAAAATCATGAAAGCACTACCTTCTCCAGTT GTAAATGATAATGAACAGAAGATGAAACTAGAGGCATTCTTACAACGGTTGTTATTTCCA GAAATTCAAGAAATGCCTACATCCCTTAATAATGACAGCAGTAATAGAAATTCAGAAGGG GGGAGCTCAAACCAACAACAACAGCACGTATCATTTGATAGCCTTTTGCAAGAGGTAAAC GACGCTTTTCCTAATACTCAATTAAATCTTAATATTCCTGTAGATGAGCATGGAAACACA CCATTACATTGGCTGACTTCAATAGCAAACCTGGAATTAGTGAAACACCTGGTTAAGCAT GGTTCAAACAGATTATATGGTGATAATATGGGGGAGTCATGCCTAGTGAAAGCTGTCAAA TCAGTAAATAATTACGACTCTGGTACTTTTGAGGCACTTCTAGATTATTTATATCCATGT TTAATTTTGGAAGACTCAATGAATAGAACAATTTTGCACCATATCATTATTACGTCTGGT ATGACTGGCTGTTCAGCAGCTGCGAAATATTATTTAGATATTTTAATGGGATGGATTGTC AAGAAACAAAATAGACCCATTCAAAGTGGTACTAACGAAAAAGAAAGCAAACCGAATGAC AAAAATGGGGAAAGAAAGGACTCTATACTAGAAAATTTGGACCTGAAATGGATAATAGCA AACATGCTCAATGCGCAGGACTCTAATGGCGATACTTGCTTGAACATTGCAGCAAGATTG GGAAACATTTCAATAGTAGACGCTTTATTAGATTACGGTGCTGACCCATTTATTGCAAAC AAATCAGGGTTGAGACCCGTGGATTTTGGGGCAGGTACTTCAAAATTACAAAATACGAAC GGCGGTGACGAAAACTCGAAGATGGTCTCTAAGGGTGATTACGACGGTCAAAAAAATGGA AAGGCCAAAAAAATAAGGTCTCAACTGTTGAAAAACCCACCTGAAACAACTTCGTTAATT AATGATGTCCAAAATTTACTGAATTCAATCTCGAAAGATTATGAGAATGAAACAGTGCAA TATAATGAGAAATTAGAAAAACTACACAAGGAATTGAACGAACAGCGAGAAGAATTAGCT AATTCTAGAGAACAACTAGCAAATGTGAAGCAATTGAAAGATGAATACTCACTAATGCAA GAGCAATTGACCAATTTAAAAGCAGGAATTGAAGAAGAAGAGGAAAGTTTTAGGGAAGAG AGCAAAAAGCTAGGAATAATTGCAGATGAAAGTTCAGGTATTGATTGGGACTCTAGCGAA TATGATGCAGATGAACCCTTCAAAGTAGAGTTCCTTTCAGATTTCTTGGAGGATAAATTA CAAAAGAATTATGAAGGCGATATTTCCAAACTATTAGAAGCGGAGTCGAAAGAGCAGATA ATGGAACAGATACGAAATCAACTTCCCGCAGAAAAAATCCAATCGATGCTTCCACCAACG GTCTTATTGAAGGCAAGAATAAATGCATACAAGCGGAATGATAAACACCTAACCAATGTA TTGGATACAATCAGCACCAAACAATCAGAATTAGAGAATAAATTTAGAAGAGTGTTATCT TTATGTTTGAAAATCGACGAAAATAAAGTTGACAATATGCTTGATGGTTTGTTACAGGCC ATATCTTCTGAAGACCCACAAGACATTGACACTGACGAAATGCAAGATTTTTTAAAAAAG CATGCTTCATGA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues803
Protein Molecular Weight90559.02
Protein Theoretical pINot Available
PDB Fileshow
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Regulatory protein SWI6 MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDTGNINETNPDSFPTDEE RNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQDAFEFEEPETDQDEEDPSH SKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGSPLKKLKIDTSVIDAESDSTP NTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFTHDLTSDFLSSPLKIMKALPSPV VNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNRNSEGGSSNQQQQHVSFDSLLQEVN DAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELVKHLVKHGSNRLYGDNMGESCLVKAVK SVNNYDSGTFEALLDYLYPCLILEDSMNRTILHHIIITSGMTGCSAAAKYYLDILMGWIV KKQNRPIQSGTNEKESKPNDKNGERKDSILENLDLKWIIANMLNAQDSNGDTCLNIAARL GNISIVDALLDYGADPFIANKSGLRPVDFGAGTSKLQNTNGGDENSKMVSKGDYDGQKNG KAKKIRSQLLKNPPETTSLINDVQNLLNSISKDYENETVQYNEKLEKLHKELNEQREELA NSREQLANVKQLKDEYSLMQEQLTNLKAGIEEEEESFREESKKLGIIADESSGIDWDSSE YDADEPFKVEFLSDFLEDKLQKNYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPT VLLKARINAYKRNDKHLTNVLDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQA ISSEDPQDIDTDEMQDFLKKHAS
References
External Links
ResourceLink
Saccharomyces Genome Database SWI6
Uniprot IDP09959
Uniprot NameSWI6
PDB ID
1SW6
General ReferenceNot Available