TOR signalling pathway: Rapamycin based repression
| Source | ID | Pathway |
|---|---|---|
| PathWhiz | PW002514 |
Pathway Metabolites
| YMDB ID | Name CAS Number | IUPAC Name | Formula Weight | Structure |
|---|---|---|---|---|
| YMDB00907 | phosphate 14265-44-2 | phosphoric acid | O4P 94.9714 |  |
| YMDB16244 | Sirolimus | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone | C51H79NO13 914.1719 |  |
Pathway Proteins
| Uniprot ID | Gene Name Locus | Name | Type | Metabolites |
|---|---|---|---|---|
| P32600 | TOR2 | Serine/threonine-protein kinase TOR2 | ||
| P18494 | GLN3 | Nitrogen regulatory protein GLN3 | Not Available | |
| P20604 | SIT4 | Serine/threonine-protein phosphatase PP1-1 | Enzyme | |
| P23202 | URE2 | Transcriptional regulator URE2 | Enzyme | Not Available |
| P35169 | TOR1 | Serine/threonine-protein kinase TOR1 | Enzyme | |
| Q04372 | TAP42 | Type 2A phosphatase-associated protein 42 | Not Available | |
| Q12199 | TIP41 | Type 2A phosphatase activator TIP41 | Not Available |