water + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol ↔ 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + Acetic acid + hydron
Thumb+6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol+Thumb+Thumb

Enzymes

  1. N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Cellular Locations

  • endoplasmic reticulum membrane
  • endoplasmic reticulum

References

  • Watanabe, R., Ohishi, K., Maeda, Y., Nakamura, N., Kinoshita, T. (1999). "Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis." Biochem J 339 ( Pt 1):185-192.10085243
  • Bowman, S., Churcher, C., Badcock, K., Brown, D., Chillingworth, T., Connor, R., Dedman, K., Devlin, K., Gentles, S., Hamlin, N., Hunt, S., Jagels, K., Lye, G., Moule, S., Odell, C., Pearson, D., Rajandream, M., Rice, P., Skelton, J., Walsh, S., Whitehead, S., Barrell, B. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Nature 387:90-93.9169872
  • Finnegan, P. M., Payne, M. J., Keramidaris, E., Lukins, H. B. (1991). "Characterization of a yeast nuclear gene, AEP2, required for accumulation of mitochondrial mRNA encoding subunit 9 of the ATP synthase." Curr Genet 20:53-61.1718609