| Identification |
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| Name | Sulfate permease 2 |
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| Synonyms | - High-affinity sulfate transporter 2
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| Gene Name | SUL2 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | Involved in secondary active sulfate transmembrane transporter activity |
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| Specific Function | High affinity uptake of sulfate into the cell |
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| Cellular Location | Membrane; Multi-pass membrane protein |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00005 | Sulfate | Show |
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| GO Classification | | Component |
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| cell part | | membrane | | membrane part | | intrinsic to membrane | | integral to membrane | | Function |
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| substrate-specific transmembrane transporter activity | | ion transmembrane transporter activity | | anion transmembrane transporter activity | | inorganic anion transmembrane transporter activity | | sulfate transmembrane transporter activity | | secondary active sulfate transmembrane transporter activity | | transporter activity | | transmembrane transporter activity | | Process |
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| establishment of localization | | transport | | ion transport | | anion transport | | inorganic anion transport | | sulfate transport | | transmembrane transport |
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| Gene Properties |
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| Chromosome Location | chromosome 12 |
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| Locus | YLR092W |
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| Gene Sequence | >2682 bp
ATGTCCAGGGAAGGTTATCCAAACTTTGAAGAGGTAGAAATTCCTGACTTTCAGGAAACT
AACAACACCGTTCCAGATCTTGATGATTTAGAATTAGAGTATGACCAATATAAAAATAAT
GAAAATAATGACACGTTTAATGATAAGGACTTAGAGAGCAATTCTGTAGCAAAGCACAAC
GCAGTGAACAGCTCAAAGGGCGTAAAAGGCTCGAAGATTGACTACTTTAATCCTTCAGAT
GTCTCGTTGTATGACAATTCCGTTTCCCAATTTGAAGAAACAACGGTATCGCTAAAAGAG
TACTATGACCACAGTATACGATCTCATCTCACGGTGAAAGGAGCATGTAGTTATCTTAAG
AGTGTTTTTCCCATCATCAACTGGCTACCACATTACAATTTTAGCTGGTTTACTGCGGAT
CTTATTGCAGGAATTACCATTGGCTGTGTTCTCGTGCCGCAATCCATGTCATATGCACAA
GTCGCCACGCTACCAGCGCAGTATGGGTTGTACTCCTCGTTTATTGGTGCTTACTCCTAC
TCTTTTTTCGCTACATCAAAAGATGTTTGTATTGGGCCCGTGGCTGTCATGTCTTTGCAG
ACCGCCAAAGTCATTGCGGATGTCACGGCAAAATATCCTGATGGAGATTCTGCCATAACT
GGTCCCGTTATTGCAACGACTCTAGCGTTACTATGTGGTATCATTTCGGCAGCAGTTGGC
TTCTTGCGTCTAGGGTTTCTTGTCGAACTGATTTCCTTAAATGCAGTCGCTGGATTTATG
ACTGGATCCGCGTTTAATATCTTATGGGGTCAAGTTCCAGCACTAATGGGTTACAATAGT
TTGGTTAACACGAGAGCTGCCACCTATAAAGTGGTCATAGAGACCTTGAAACATTTACCA
GATACCAAACTGGACGCAGTTTTTGGGCTAATCCCGCTTTTCCTTCTTTATGTTTGGAAA
TGGTGGTGCGGAACATATGGACCAAGGTTGAACGATAGATACAACTCCAAAAACCCAAGG
TTACACAAAATTATCAAATGGACATATTTTTACGCTCAGGCTTCCAGAAATGGTATCATT
ATTATTGTATTCACTTGTATTGGTTGGGCAATCACAAGAGGCAAATCTAAATCGGAGAGG
CCCATCAGCATCCTAGGCTCAGTTCCATCCGGTTTGAAAGAAGTCGGGGTTTTCCATGTT
CCACCAGGATTAATGTCTAAGCTTGGTCCAAATTTGCCTGCATCCATTATTGTGTTATTG
TTGGAGCATATCGCTATTTCGAAGTCTTTTGGTAGAATCAACGACTATAAAGTCGTCCCC
GACCAAGAATTGATTGCTATTGGTGTCTCGAACCTTTTAGGTACTTTCTTCAATGCTTAC
CCAGCGACTGGTTCCTTTTCAAGGTCTGCTTTGAAGGCTAAATGTAATGTCCGTACGCCG
TTATCTGGTTTGTTTTCGGGTTCATGTGTTCTTTTAGCATTATATTGTTTGACCGGCGCA
TTCTTTTACATTCCAAAGGCTACCTTATCTGCAGTTATCATTCACGCTGTATCTGATCTT
TTGGCCTCTTATCAAACTACCTGGAATTTCTGGAAGATGAATCCATTGGACTTCATCTGT
TTCATTGTCACCGTCCTAATAACGGTATTTGCCTCTATTGAAGATGGTATTTATTTTGCC
ATGTGCTGGTCATGTGCAATGCTCATTTTAAAAGTGGCTTTCCCAGCGGGAAAATTCTTG
GGTCGTGTGGAAGTCGCTGAAGTTACTGATGCTTACGTCAGACCGGACTCCGATGTGGTT
AGCTACGTGTCTGAAAATAACAATGGTATTTCCACTTTAGAAGATGGTGGTGAGGATGAC
AAGGAAAGTTCCACCAAATACGTCACAAATTCCTCCAAGAAAATAGAAACAAACGTTCAA
ACAAAGGGCTTTGATTCTCCATCTTCTTCGATTAGCCAGCCAAGGATAAAATACCATACT
AAATGGATACCGTTTGATCATAAATACACAAGAGAATTGAACCCGGACGTTCAGATTCTC
CCCCCACCAGACGGTGTTCTTGTTTATAGGCTATCAGAGAGCTACACCTATCTCAACTGT
TCCAGACACTACAACATCATAACCGAAGAAGTTAAAAAAGTTACCAGACGTGGTCAATTA
ATTCGCCACAGAAAAAAATCTGACCGTCCATGGAATGATCCTGGTCCATGGGAAGCACCT
GCTTTCTTAAAGAATTTGAAATTCTGGAAGAAAAGGGAGAACGACCCTGAATCCATGGAA
AACGCGCCCAGCACCTCAGTCGATGTTGAAAGAGATGACAGGCCATTGCTGAAAATACTA
TGCTTAGACTTCTCACAAGTGGCACAGACAGACGCTACGGCTCTTCAATCATTGGTTGAT
TTGAGAAAGGCCATAAATCAATATGCAGATAGGCAAGTTGAATTCCACTTTGTGGGTATC
ATTTCACCATGGGTGAAGAGAGGTTTAATTAGCAGAGGATTTGGTACTCTGAACGAAGAA
TACAGTGATGAATCCATTGTTGCCGGTCATACAAGTTATCACGTCGCCAGAGTACCTCAA
GGCGAAGAAAATCCTGAAAAATATAGCGTTTATACCGCTTCAGGAACAAATCTACCTTTC
TTCCATATCGATATCCCAGATTTTGCTAAATGGGATATCTAG |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 893 |
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| Protein Molecular Weight | 99649.79688 |
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| Protein Theoretical pI | 6.65 |
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| Signalling Regions | |
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| Transmembrane Regions | - 132-152
- 164-184
- 189-209
- 222-242
- 245-265
- 306-326
- 351-371
- 400-420
- 444-464
- 484-504
- 533-551
- 560-580
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| Protein Sequence | >Sulfate permease 2
MSREGYPNFEEVEIPDFQETNNTVPDLDDLELEYDQYKNNENNDTFNDKDLESNSVAKHN
AVNSSKGVKGSKIDYFNPSDVSLYDNSVSQFEETTVSLKEYYDHSIRSHLTVKGACSYLK
SVFPIINWLPHYNFSWFTADLIAGITIGCVLVPQSMSYAQVATLPAQYGLYSSFIGAYSY
SFFATSKDVCIGPVAVMSLQTAKVIADVTAKYPDGDSAITGPVIATTLALLCGIISAAVG
FLRLGFLVELISLNAVAGFMTGSAFNILWGQVPALMGYNSLVNTRAATYKVVIETLKHLP
DTKLDAVFGLIPLFLLYVWKWWCGTYGPRLNDRYNSKNPRLHKIIKWTYFYAQASRNGII
IIVFTCIGWAITRGKSKSERPISILGSVPSGLKEVGVFHVPPGLMSKLGPNLPASIIVLL
LEHIAISKSFGRINDYKVVPDQELIAIGVSNLLGTFFNAYPATGSFSRSALKAKCNVRTP
LSGLFSGSCVLLALYCLTGAFFYIPKATLSAVIIHAVSDLLASYQTTWNFWKMNPLDFIC
FIVTVLITVFASIEDGIYFAMCWSCAMLILKVAFPAGKFLGRVEVAEVTDAYVRPDSDVV
SYVSENNNGISTLEDGGEDDKESSTKYVTNSSKKIETNVQTKGFDSPSSSISQPRIKYHT
KWIPFDHKYTRELNPDVQILPPPDGVLVYRLSESYTYLNCSRHYNIITEEVKKVTRRGQL
IRHRKKSDRPWNDPGPWEAPAFLKNLKFWKKRENDPESMENAPSTSVDVERDDRPLLKIL
CLDFSQVAQTDATALQSLVDLRKAINQYADRQVEFHFVGIISPWVKRGLISRGFGTLNEE
YSDESIVAGHTSYHVARVPQGEENPEKYSVYTASGTNLPFFHIDIPDFAKWDI |
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| References |
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| External Links | |
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| General Reference | - Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
- Cherest, H., Davidian, J. C., Thomas, D., Benes, V., Ansorge, W., Surdin-Kerjan, Y. (1997). "Molecular characterization of two high affinity sulfate transporters in Saccharomyces cerevisiae." Genetics 145:627-635.9055073
- Kim, H., Melen, K., Osterberg, M., von Heijne, G. (2006). "A global topology map of the Saccharomyces cerevisiae membrane proteome." Proc Natl Acad Sci U S A 103:11142-11147.16847258
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