| Identification |
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| Name | NADH pyrophosphatase |
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| Synonyms | Not Available |
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| Gene Name | NPY1 |
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| Enzyme Class | |
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| Biological Properties |
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| General Function | Involved in hydrolase activity |
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| Specific Function | NAD(+) + H(2)O = AMP + NMN |
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| Cellular Location | Cytoplasmic |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | | Nicotinate and nicotinamide metabolism | ec00760 |  |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | |
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| Metabolites | | YMDB ID | Name | View |
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| YMDB00097 | Adenosine monophosphate | Show | | YMDB00110 | NAD | Show | | YMDB00138 | Nicotinamide ribotide | Show | | YMDB00412 | NAD(+) | Show | | YMDB00862 | hydron | Show | | YMDB00890 | water | Show |
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| GO Classification | | Component |
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| Not Available | | Function |
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| metal ion binding | | hydrolase activity | | catalytic activity | | binding | | ion binding | | cation binding | | Process |
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| Not Available |
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| Gene Properties |
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| Chromosome Location | chromosome 7 |
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| Locus | YGL067W |
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| Gene Sequence | >1155 bp
ATGTCCACTGCTGTGACTTTTTTTGGCCAGCATGTCTTGAACAGAGTTTCGTTCTTAAGA
TGTTCGAAAGAGTTCATCAAAAAATCATTGAACCATGACTCTACCGTTTTTATCCCATTT
ATCGAAGGGGAAGCCCTCATTTCGCCCGAAAATGGTGACCTAGTTCAGCTTTCTAATTCT
GTAAAGTCTTACAAGAATATTTTGTCAGCAATAGTTCCTTTATACACTACTTTATTGAAC
ACAACTCGCTCAAGAAGCGATGAATCAGGCATCAATGTAACATTTTTAGGTCTCCTGGAA
GGCACAGATTCTGCATTTAATTTTGAATGGTCTAATATTTCTTACAAAGGAACACCATAT
TTTGGATTAGATATCCGTGTTACTGAGAGCACACTCTTCAAGAAAGTCGACTTTGAGCCT
ATTTTTTCCTATCCGAAGGTGACCAGAGATCACATTTTCAAACAAACAAATGAGGATGCT
TCACTTTATTCACAAGGTAAGATGTATCTGGATTGGCTAGCAAAGTACAAATTCTGTCCC
GGTTGTGGGTCTCCGTTATTCCCAGTAGAGGCAGGAACTAAGCTTCAGTGTTCTAATGAA
AATCGGAATGTATACTGTAATGTGAGAGATGCAAGAATTAATAACGTTTGCTTCCCAAGA
ACTGATCCAACGGTCATTATAGCCTTGACCAATTCGGATTACTCTAAGTGTTGTCTGGCA
AGATCAAAAAAAAGGTACGGTGATTTTGTATTGTATTCAACAATAGCAGGTTTTATGGAG
CCATCAGAAACCATAGAGGAGGCTTGTATCAGAGAAATATGGGAGGAAACAGGCATTTCA
TGCAAAAATATTGATATAGTCCGGTCACAGCCCTGGCCTTACCCTTGCAGTTTGATGATT
GGCTGTTTAGGCATAGTTCAATTCAATTCCAAAAATGAGGTTATCAACCTGAATCATGAC
GACGAATTATTGGATGCTCAATGGTTTGATACAACTGAAATCATTCAAGCTTTGGATAAG
TACGCCGGCGGGTATCGTGTTCCATTCAAAAATGATATCAATTTACCTGGAAGTACTACC
ATTGCCTTCCAATTAATCAATCATGTTTGCGAGAACTATAAAAACTTACGTAAGACCTCA
TCGAGCCATCTATAG |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 384 |
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| Protein Molecular Weight | 43516.0 |
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| Protein Theoretical pI | 6.25 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >NADH pyrophosphatase
MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGEALISPENGDLVQLSNS
VKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGTDSAFNFEWSNISYKGTPY
FGLDIRVTESTLFKKVDFEPIFSYPKVTRDHIFKQTNEDASLYSQGKMYLDWLAKYKFCP
GCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCFPRTDPTVIIALTNSDYSKCCLA
RSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEETGISCKNIDIVRSQPWPYPCSLMI
GCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEIIQALDKYAGGYRVPFKNDINLPGSTT
IAFQLINHVCENYKNLRKTSSSHL |
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| References |
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| External Links | |
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| General Reference | - Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
- Xu, W., Dunn, C. A., Bessman, M. J. (2000). "Cloning and characterization of the NADH pyrophosphatases from Caenorhabditis elegans and Saccharomyces cerevisiae, members of a Nudix hydrolase subfamily." Biochem Biophys Res Commun 273:753-758.10873676
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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