ATP synthase subunit H, mitochondrial (Q12349)

Identification
NameATP synthase subunit H, mitochondrial
SynonymsNot Available
Gene NameATP14
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in protein binding
Specific FunctionMitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane
Cellular LocationMitochondrion. Mitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO ClassificationNot Available
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>375 bp ATGTTCCCTATCGCTTCCAGAAGAATACTGCTCAATGCTTCAGTTCTGCCATTGAGACTG TGCAATAGAAATTTCACTACCACAAGAATATCCTACAACGTCATACAAGATTTGTATTTG AGGGAACTAAAAGACACCAAACTGGCTCCAAGTACCTTGCAAGATGCTGAAGGTAATGTT AAGCCTTGGAACCCACCACAAAAACCAAATCTACCAGAATTGGAACTTCAAGGCCCAGAG GCTTTAAAGGCTTACACCGAGCAAAATGTAGAAACTGCTCATGTTGCTAAAGAGTCTGAA GAGGGTGAGTCAGAGCCAATTGAAGAGGATTGGCTAGTTTTGGATGATGCTGAGGAAACC AAAGAAAGTCATTGA
Protein Properties
Pfam Domain Function
Protein Residues124
Protein Molecular Weight14127.7002
Protein Theoretical pI4.34
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>ATP synthase subunit H, mitochondrial MFPIASRRILLNASVLPLRLCNRNFTTTRISYNVIQDLYLRELKDTKLAPSTLQDAEGNV KPWNPPQKPNLPELELQGPEALKAYTEQNVETAHVAKESEEGESEPIEEDWLVLDDAEET KESH
References
External Links
ResourceLink
Saccharomyces Genome Database ATP14
Uniprot IDQ12349
Uniprot NameATP14_YEAST
GenBank Gene IDAY558215
Genebank Protein ID45270320
General Reference
  • Arselin, G., Vaillier, J., Graves, P. V., Velours, J. (1996). "ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene." J Biol Chem 271:20284-20290.8702761
  • Johnston, M., Hillier, L., Riles, L., Albermann, K., Andre, B., Ansorge, W., Benes, V., Bruckner, M., Delius, H., Dubois, E., Dusterhoft, A., Entian, K. D., Floeth, M., Goffeau, A., Hebling, U., Heumann, K., Heuss-Neitzel, D., Hilbert, H., Hilger, F., Kleine, K., Kotter, P., Louis, E. J., Messenguy, F., Mewes, H. W., Hoheisel, J. D., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Nature 387:87-90.9169871
  • Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106