Ubiquinone biosynthesis monooxygenase COQ6 (P53318)

Identification
NameUbiquinone biosynthesis monooxygenase COQ6
SynonymsNot Available
Gene NameCOQ6
Enzyme ClassNot Available
Biological Properties
General FunctionCoenzyme transport and metabolism
Specific FunctionNot Available
Cellular LocationMitochondrion inner membrane; Peripheral membrane protein; Matrix side
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
binding
catalytic activity
oxidoreductase activity
monooxygenase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
FAD or FADH2 binding
Process
metabolic process
oxidation reduction
cellular metabolic process
cofactor metabolic process
coenzyme metabolic process
oxidoreduction coenzyme metabolic process
ubiquinone metabolic process
ubiquinone biosynthetic process
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1440 bp ATGTTCTTTTCAAAAGTTATGCTTACTCGGCGTATTTTGGTGAGGGGTTTGGCAACAGCC AAATCTTCAGCTCCAAAGTTAACAGATGTATTAATCGTAGGTGGGGGTCCTGCAGGTTTG ACTTTAGCTGCATCGATTAAGAATTCTCCGCAATTAAAAGATCTAAAGACAACTTTAGTC GATATGGTGGACTTAAAAGATAAATTATCGGACTTTTATAATTCACCCCCAGATTATTTT ACGAACAGGATTGTCAGTGTTACGCCTAGATCTATTCATTTTCTTGAGAATAACGCTGGG GCAACTTTGATGCATGACAGGATTCAAAGTTATGACGGACTCTATGTCACGGACGGTTGT TCTAAGGCTACTTTGGATCTGGCAAGGGACTCCATGCTTTGTATGATTGAAATTATAAAT ATACAGGCCTCCTTATACAACAGAATTTCTCAGTACGATTCAAAGAAGGACTCCATTGAT ATTATTGATAATACAAAAGTTGTCAATATTAAACACAGCGACCCTAATGATCCATTGTCC TGGCCTTTAGTCACTCTTTCCAATGGTGAAGTATACAAGACGAGATTGCTAGTGGGTGCA GACGGGTTCAATTCTCCTACCAGAAGATTTTCCCAGATCCCATCTAGGGGCTGGATGTAT AATGCCTATGGTGTTGTGGCCAGCATGAAGTTAGAGTATCCTCCCTTTAAACTAAGGGGC TGGCAGAGGTTCTTACCCACTGGTCCAATTGCACACTTACCCATGCCTGAAAATAATGCT ACTTTAGTCTGGAGTTCATCTGAACGTTTATCGAGGCTTTTGTTGTCATTACCTCCAGAA TCATTCACTGCACTTATCAATGCTGCTTTTGTCTTGGAAGACGCAGACATGAACTACTAT TACCGTACATTGGAAGATGGCTCTATGGACACCGATAAATTGATAGAAGATATTAAATTC AGAACTGAGGAAATATACGCCACGTTGAAGGACGAGTCGGATATTGATGAAATTTACCCA CCAAGAGTTGTTAGTATAATAGATAAGACAAGAGCACGTTTTCCCTTAAAATTAACACAT GCAGATCGTTATTGCACTGATAGAGTTGCCCTTGTTGGGGACGCAGCACATACGACACAT CCTCTCGCTGGACAGGGGTTAAACATGGGGCAAACAGACGTTCATGGTTTAGTATACGCT TTAGAAAAGGCAATGGAAAGAGGTTTAGACATTGGCTCTTCATTGAGCTTAGAACCCTTT TGGGCAGAAAGATATCCGTCGAACAACGTTCTATTAGGAATGGCGGATAAATTATTTAAA TTATATCACACTAATTTTCCTCCTGTGGTAGCCCTAAGAACTTTTGGTTTGAATCTGACG AATAAGATCGGTCCAGTTAAGAATATGATCATTGACACATTAGGAGGAAATGAGAAATGA
Protein Properties
Pfam Domain Function
Protein Residues479
Protein Molecular Weight53526.80078
Protein Theoretical pI7.02
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Ubiquinone biosynthesis monooxygenase COQ6 MFFSKVMLTRRILVRGLATAKSSAPKLTDVLIVGGGPAGLTLAASIKNSPQLKDLKTTLV DMVDLKDKLSDFYNSPPDYFTNRIVSVTPRSIHFLENNAGATLMHDRIQSYDGLYVTDGC SKATLDLARDSMLCMIEIINIQASLYNRISQYDSKKDSIDIIDNTKVVNIKHSDPNDPLS WPLVTLSNGEVYKTRLLVGADGFNSPTRRFSQIPSRGWMYNAYGVVASMKLEYPPFKLRG WQRFLPTGPIAHLPMPENNATLVWSSSERLSRLLLSLPPESFTALINAAFVLEDADMNYY YRTLEDGSMDTDKLIEDIKFRTEEIYATLKDESDIDEIYPPRVVSIIDKTRARFPLKLTH ADRYCTDRVALVGDAAHTTHPLAGQGLNMGQTDVHGLVYALEKAMERGLDIGSSLSLEPF WAERYPSNNVLLGMADKLFKLYHTNFPPVVALRTFGLNLTNKIGPVKNMIIDTLGGNEK
References
External Links
ResourceLink
Saccharomyces Genome Database COQ6
Uniprot IDP53318
Uniprot NameCOQ6_YEAST
GenBank Gene IDAF003698
Genebank Protein ID2198818
General Reference
  • Gin, P., Hsu, A. Y., Rothman, S. C., Jonassen, T., Lee, P. T., Tzagoloff, A., Clarke, C. F. (2003). "The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis." J Biol Chem 278:25308-25316.12721307
  • Mazzoni, C., Ruzzi, M., Rinaldi, T., Solinas, F., Montebove, F., Frontali, L. (1997). "Sequence analysis of a 10.5 kb DNA fragment from the yeast chromosome VII reveals the presence of three new open reading frames and of a tRNAThr gene." Yeast 13:369-372.9133741
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106