Protein MTL1 (P53214)

Identification
NameProtein MTL1
Synonyms
  • MID two-like protein 1
Gene NameMTL1
Enzyme ClassNot Available
Biological Properties
General Functionfungal-type cell wall organization
Specific FunctionInvolved in cell integrity signaling during vegetative growth at elevated temperature. Acts positively on the PKC1-MAPK pathway. Cell membrane sensor of oxidative stress in the cell integrity pathway upstream of PKC1. Required to transmit the oxidative signal to SLT2 and to restore the correct actin organization following oxidative stress. Multicopy suppressor of 1,3-beta-glucan synthase (GS) mutation. Also suppresses RGD1 null mutations.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
integral component of plasma membrane
cellular response to oxidative stress
fungal-type cell wall organization
cellular response to glucose starvation
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1656 bp ATGGCAAGCTGCAATCCGACCAGGAAGAAGAGCTCTGCTTCAAGCCTATCTATGTGGAGA ACGATTCTCATGGCGTTAACAACACTACCGCTAAGTGTTCTTTCGCAGGAGTTGGTTCCA GCTAATAGCACAACATCGAGCACAGCTCCTTCCATCACTTCGCTTTCCGCAGTTGAGTCA TTTACGTCCAGTACCGATGCAACGAGCAGCGCAAGTTTATCAACGCCGAGTATAGCTTCA GTATCCTTTACTTCCTTCCCACAAAGTTCTTCACTGCTTACTCTTTCGTCAACATTATCC TCAGAACTTTCCTCTTCGTCCATGCAAGTTTCGTCGTCTTCAACATCGTCGTCTTCTTCG GAGGTTACGTCATCATCGTCATCATCATCAATATCTCCTTCCTCTTCATCATCAACAATA ATATCATCGTCATCATCACTGCCGACATTCACTGTGGCATCAACATCTTCGACAGTTGCC TCCTCCACACTTTCCACTAGCTCATCGTTGGTTATCTCTACGTCTTCGTCAACGTTTACG TTTAGTTCGGAAAGTTCAAGCTCTTTGATTTCCTCTTCAATTTCAACATCCGTTTCGACT TCTTCAGTGTACGTTCCCTCCTCTTCAACTTCATCTCCACCTTCGTCCTCATCCGAATTG ACATCATCCTCGTACTCATCATCCTCATCCTCATCCACCCTCTTTTCCTACTCCTCCTCA TTTTCATCATCCTCATCCTCATCATCCTCATCATCATCCTCATCCTCATCATCATCATCA TCATCATCATCATATTTCACCCTCTCCACATCTTCCTCTTCATCCATATACTCGTCTTCG TCATATCCTTCATTTTCATCTTCATCTTCCTCAAACCCTACCTCATCAATCACTTCTACA TCCGCCTCATCTTCTATTACTCCCGCTTCCGAATATTCCAATTTGGCAAAAACCATAACT AGTATAATAGAAGGCCAGACCATCCTCTCTAACTACTATACCACAATAACGTATTCACCG ACAGCATCCGCATCTTCAGGAAAAAATTCACATCACTCAGGCTTATCAAAAAAGAATCGT AATATTATCATCGGTTGTGTGGTTGGCATAGGTGCCCCCCTCATCCTAATTCTACTAATA TTGATTTACATGTTTTGTGTTCAGCCTAAAAAAACGGATTTCATTGACTCTGACGGTAAA ATTGTCACAGCTTATCGTAGTAACATTTTCACCAAAATATGGTATTTCTTGCTGGGTAAA AAAATTGGTGAAACAGAAAGATTCAGCTCAGATTCCCCCATCGGCAGCAATAATATTCAG AATTTTGGTGATATCGATCCAGAAGATATACTTAACAATGACAACCCCTACACCCCTAAA CACACTAATGTTGAAGGCTACGACGACGACGACGACGACGACGCTAATGATGAAAACCTA TCATCCAACTTCCATAACAGAGGCATAGATGATCAATACTCACCTACTAAATCTGCATCA TATTCAATGTCGAATAGTAATAGTCAAGATTACAACGACGCAGATGAAGTAATGCACGAT GAAAACATTCATCGTGTTTATGATGACAGCGAAGCTAGCATCGACGAGAACTATTACACG AAACCAAACAACGGCTTAAATATCACGAACTATTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues551
Protein Molecular Weight57526.68
Protein Theoretical pINot Available
Signalling Regions
  • 1-35
Transmembrane Regions
  • 362-382
Protein Sequence>Protein MTL1 MASCNPTRKKSSASSLSMWRTILMALTTLPLSVLSQELVPANSTTSSTAPSITSLSAVES FTSSTDATSSASLSTPSIASVSFTSFPQSSSLLTLSSTLSSELSSSSMQVSSSSTSSSSS EVTSSSSSSSISPSSSSSTIISSSSSLPTFTVASTSSTVASSTLSTSSSLVISTSSSTFT FSSESSSSLISSSISTSVSTSSVYVPSSSTSSPPSSSSELTSSSYSSSSSSSTLFSYSSS FSSSSSSSSSSSSSSSSSSSSSSSYFTLSTSSSSSIYSSSSYPSFSSSSSSNPTSSITST SASSSITPASEYSNLAKTITSIIEGQTILSNYYTTITYSPTASASSGKNSHHSGLSKKNR NIIIGCVVGIGAPLILILLILIYMFCVQPKKTDFIDSDGKIVTAYRSNIFTKIWYFLLGK KIGETERFSSDSPIGSNNIQNFGDIDPEDILNNDNPYTPKHTNVEGYDDDDDDDANDENL SSNFHNRGIDDQYSPTKSASYSMSNSNSQDYNDADEVMHDENIHRVYDDSEASIDENYYT KPNNGLNITNY
References
External Links
ResourceLink
Saccharomyces Genome Database MTL1
Uniprot IDP53214
Uniprot NameMTL1
General ReferenceNot Available