| Identification |
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| Name | GPI transamidase component GPI16 |
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| Synonyms | Not Available |
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| Gene Name | GPI16 |
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| Enzyme Class | Not Available |
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| Biological Properties |
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| General Function | Involved in GPI-anchor transamidase activity |
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| Specific Function | Component of the GPI transamidase complex. Involved in transfer of GPI to proteins |
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| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
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| SMPDB Pathways | Not Available |
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| KEGG Pathways | Not Available |
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| SMPDB Reactions | Not Available |
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| KEGG Reactions | Not Available |
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| Metabolites | |
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| GO Classification | | Component |
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| cell part | | membrane part | | intrinsic to membrane | | integral to membrane | | macromolecular complex | | protein complex | | GPI-anchor transamidase complex |
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| Gene Properties |
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| Chromosome Location | Not Available |
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| Locus | |
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| Gene Sequence | >YHR188C Chr 8
ATGATCCTCACACTGGCCTATTTCATGCTGGGCACTCTACTACTGGGTGTGTTCGCAGAA
GACACGGTGTCGCAGATTGGTATAAATGACAGTTTATGGTATCCGTACGACGAAGCACTG
GTGTTGAAGCCGCTGCCCAACAATGATCTGCTACTCTCATTTGCATTCCAACTGCAATCG
GAACCGTTTGACCCGGCCGTATCATCCATGTCATATGATGCGTATGAGCACTACACGACT
TTCCCACGGGCCATCCCACCATTGTTGGAATCTACTGCCACGCGTCAGTTTCATTTAAGA
TTTACCAGAGGATTCTGGGATGCCCTGTCGTGGGGACAGTTGCCACATGCTGGAAAAGAG
GCAGGTGCCTCAGGTGTGGAATTGTGGTCGCAAGTGCAGGCCATGGATCAGGAACAGGCG
TTCCATAATTGGAAAAAACTGTCCAATTCATTGAGCGGATTGTTTTGTTCTTCTTTAAAT
TTTATCGACGAGTCAAGGACGACCTTTCCCCGGCGGTCATATGCTTCTGATATAGGAGCT
CCTCTTTTCAATAGCACCGAGAAACTGTACCTGATGCGAGCATCGTTGCCCAATGAACCC
ATCTGTACCGAGAACTTGACGCCGTTCATAAAACTATTGCCTACTAGGGGCAAATCCGGT
TTGACATCTCTCTTGGATGGTCATAAATTGTTCGACTCTCTATGGAATAGTATTTCCTTG
GATATTGCCACTATTTGTTCTGAAGATGAAGATGCTCTTTGTCACTACGAGATGGACGCA
CGCATAGAAATGGTAACACACGTTCCCTCCGCCTTGGCAAGAGGTGAGAGACCTATCCCC
AAACCTTTGGATGGGAACACATTGCGTTGTGACACGGATAAACCCTTTGATTCTTACCAA
TGCTTCCCTCTACCGGAACCTTCGCAGACTCACTTCAAGCTGTCTCAGCTGTTTGCCAGA
CCAATAAACAATGGCAACCTGTTTGCTAATAGGCCCACAAGAATTTGTGCAGAAGTTGAC
CGTTCTACCTGGACTGCGTTTTTGTCAGTTGACGATACTATTTTCAGCACACATGATAAT
TGCTTTGACTTATCAAACGATCAAAATGAGGGTGGTTCGGGCTACGACTTTATTTTAGAA
TCGACGGACACTACTAAAGTTACTCCCATAGTTCCTGTCCCAATTCACGTAAGCAGATCT
CTGACTGGTAATGGACAAGATCGTGGTGGAATGCGTATTGTTTTCCATAACGACAATGAT
ACCCCTGTGAAGTTGATTTATTTCGAATCATTGCCATGGTTCATGAGAGTTTACCTATCC
TCTCTTCAAATTACTTCTACTACCTCTCCGCAATTGCAAGAAAACGATATCATCTTAGAT
AAATACTATTTACAAGCGGCCGATAGAAAAAGACCTGGCCACTTGGAGTTCACGATGTTA
ATTCCAGCTAATACGGACATTGTAATGACTTATCAATTCGATAAAGCTCTTCTGCAATTT
GCCGAGTATCCACCAGATGCAAACCATGGTTTTGAAATCGATGCAGCTGTAATCACCGTG
CTATCTTTGGAGTCCTCATCGTCTCTTTATGAAATGAGAACCTCTACCCTATTGTTATCC
CTGTCTACACCGGATTTTAGTATGCCGTATAACGTCATCATTCTAACATCTACAATCATG
GGACTCATATTCGGTATGCTATACAATTTGATGGTGAAGAGAATGGTCACCGTCGAAGAG
GCCGATAAGATTACGTTGCAATCTGGCTTAAAATACAAATTGCTAAAGCTAAAGGAAAAG
TTCCTAGGGAAAAAAAAGACTAAAACAGACTAA |
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| Protein Properties |
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| Pfam Domain Function | |
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| Protein Residues | 610 |
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| Protein Molecular Weight | 68770.60156 |
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| Protein Theoretical pI | 4.94 |
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| Signalling Regions | |
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| Transmembrane Regions | |
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| Protein Sequence | >GPI transamidase component GPI16
MILTLAYFMLGTLLLGVFAEDTVSQIGINDSLWYPYDEALVLKPLPNNDLLLSFAFQLQS
EPFDPAVSSMSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKE
AGASGVELWSQVQAMDQEQAFHNWKKLSNSLSGLFCSSLNFIDESRTTFPRRSYASDIGA
PLFNSTEKLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISL
DIATICSEDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLRCDTDKPFDSYQ
CFPLPEPSQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLSVDDTIFSTHDN
CFDLSNDQNEGGSGYDFILESTDTTKVTPIVPVPIHVSRSLTGNGQDRGGMRIVFHNDND
TPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQENDIILDKYYLQAADRKRPGHLEFTML
IPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVITVLSLESSSSLYEMRTSTLLLS
LSTPDFSMPYNVIILTSTIMGLIFGMLYNLMVKRMVTVEEADKITLQSGLKYKLLKLKEK
FLGKKKTKTD |
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| References |
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| External Links | |
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| General Reference | - Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
- Ohishi, K., Inoue, N., Kinoshita, T. (2001). "PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8." EMBO J 20:4088-4098.11483512
- Fraering, P., Imhof, I., Meyer, U., Strub, J. M., van Dorsselaer, A., Vionnet, C., Conzelmann, A. (2001). "The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p." Mol Biol Cell 12:3295-3306.11598210
- Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
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