Tyrosine-protein phosphatase MSG5 (P38590)

Identification
NameTyrosine-protein phosphatase MSG5
SynonymsNot Available
Gene NameMSG5
Enzyme ClassNot Available
Biological Properties
General Functionregulation of MAPK export from nucleus
Specific FunctionDual specificity phosphatase that dephosphorylates MAP kinase FUS3 on both a Tyr and a Ser or Thr. Has a role in adaptation to pheromone.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: cell wall stress test 1PW007861 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: pheromone stress test 1PW012843 ThumbThumb?image type=greyscaleThumb?image type=simple
Stress-activated signalling pathways: starvation test 1PW003483 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
cell cycle
protein tyrosine phosphatase activity
protein dephosphorylation
inactivation of MAPK activity involved in cell wall organization or biogenesis
MAP kinase tyrosine/serine/threonine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
inactivation of MAPK activity involved in conjugation with cellular fusion
regulation of MAPK export from nucleus
nucleus
cytoplasm
regulation of fungal-type cell wall organization
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>1470 bp ATGCAATTTCACTCAGATAAGCAGCATTTGGACAGTAAAACCGACATCGATTTCAAGCCA AACTCACCGCGTTCCTTACAAAATAGGAATACCAAAAATTTATCTTTAGATATAGCAGCA CTCCATCCATTAATGGAATTCTCATCGCCAAGCCAAGATGTGCCAGGTTCAGTAAAATTC CCATCGCCGACACCTTTGAATCTATTTATGAAGCCCAAACCTATTGTGTTGGAGAAATGT CCACCAAAAGTAAGTCCAAGGCCAACGCCACCATCGCTGTCGATGAGGCGAAGCGAGGCC TCTATATACACACTACCAACATCTTTGAAGAACCGAACTGTTTCTCCAAGCGTGTATACA AAATCATCCACAGTATCGTCTATCAGTAAGCTGTCATCATCATCACCGTTATCGTCATTT TCAGAAAAACCTCATCTGAATAGAGTCCATTCATTATCCGTGAAAACTAAAGACTTGAAG TTGAAGGGAATTAGAGGACGTTCTCAAACGATCTCAGGGTTAGAGACATCCACGCCAATT TCTAGTACTCGTGAAGGTACTTTAGATAGTACGGATGTCAACAGATTTTCTAACCAAAAG AATATGCAAACAACATTGATTTTCCCGGAGGAGGACTCGGATCTGAATATTGATATGGTG CATGCAGAGATTTATCAACGAACGGTTTATTTAGATGGACCATTGCTGGTACTGCCGCCT AATTTGTATCTATATTCAGAACCCAAACTAGAAGATATATTATCGTTTGATTTAGTCATT AATGTTGCCAAAGAAATACCGAACCTGGAGTTTTTAATACCGCCGGAAATGGCACATAAA ATAAAATATTACCATATTGAATGGACACACACATCCAAGATCGTCAAGGACTTATCCCGA TTGACACGCATTATACATACCGCTCATTCGCAAGGCAAGAAAATACTCGTACACTGTCAG TGTGGAGTATCAAGATCGGCGTCATTGATTGTGGCGTATATCATGCGATATTATGGCTTG AGTTTAAATGATGCATACAATAAGCTGAAAGGTGTTGCTAAGGATATAAGTCCAAACATG GGTCTCATCTTCCAACTTATGGAATGGGGAACCATGTTGTCCAAGAACTCACCGGGCGAA GAAGGAGAGACTGTTCACATGCCTGAGGAAGATGACATCGGAAACAACGAAGTTTCCTCG ACTACGAAGTCCTACTCTTCTGCGTCCTTTAGAAGTTTTCCCATGGTAACGAATCTATCA TCGTCGCCGAATGACAGTTCTGTCAATTCTTCGGAAGTAACGCCAAGAACTCCTGCTACG TTGACTGGAGCAAGGACCGCACTGGCCACAGAACGCGGGGAAGATGATGAGCACTGTAAA AGTTTGTCTCAACCCGCAGATTCACTGGAAGCTTCTGTGGACAACGAATCAATATCTACT GCCCCGGAACAGATGATGTTTCTTCCTTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues489
Protein Molecular Weight54216.91
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Tyrosine-protein phosphatase MSG5 MQFHSDKQHLDSKTDIDFKPNSPRSLQNRNTKNLSLDIAALHPLMEFSSPSQDVPGSVKF PSPTPLNLFMKPKPIVLEKCPPKVSPRPTPPSLSMRRSEASIYTLPTSLKNRTVSPSVYT KSSTVSSISKLSSSSPLSSFSEKPHLNRVHSLSVKTKDLKLKGIRGRSQTISGLETSTPI SSTREGTLDSTDVNRFSNQKNMQTTLIFPEEDSDLNIDMVHAEIYQRTVYLDGPLLVLPP NLYLYSEPKLEDILSFDLVINVAKEIPNLEFLIPPEMAHKIKYYHIEWTHTSKIVKDLSR LTRIIHTAHSQGKKILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNM GLIFQLMEWGTMLSKNSPGEEGETVHMPEEDDIGNNEVSSTTKSYSSASFRSFPMVTNLS SSPNDSSVNSSEVTPRTPATLTGARTALATERGEDDEHCKSLSQPADSLEASVDNESIST APEQMMFLP
References
External Links
ResourceLink
Saccharomyces Genome Database MSG5
Uniprot IDP38590
Uniprot NameMSG5
General ReferenceNot Available