Identification
NameCytochrome b-c1 complex subunit 10
Synonyms
  • Complex III subunit 10
  • Complex III subunit XI
  • Ubiquinol-cytochrome c reductase complex 8.5 kDa protein
Gene NameQCR10
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in aerobic respiration
Specific FunctionComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c. QCR10 is required for stable association of the iron-sulfur protein with the complex
Cellular LocationMitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO ClassificationNot Available
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>234 bp ATGGCGTACACTTCTCATCTGTCTTCAAAAACTGGTCTACATTTCGGTAGACTTTCTTTA AGAAGTTTAACAGCTTATGCTCCGAATTTAATGTTATGGGGTGGTGCTAGCATGCTTGGG CTATTTGTATTCACAGAAGGATGGCCTAAGTTTCAAGATACGCTATACAAAAAGATTCCG TTGTTAGGACCTACATTGGAAGATCATACTCCACCAGAAGATAAACCTAATTGA
Protein Properties
Pfam Domain Function
Protein Residues77
Protein Molecular Weight8592.90039
Protein Theoretical pI8.99
Signalling Regions
  • None
Transmembrane Regions
  • 25-45
Protein Sequence>Cytochrome b-c1 complex subunit 10 MAYTSHLSSKTGLHFGRLSLRSLTAYAPNLMLWGGASMLGLFVFTEGWPKFQDTLYKKIP LLGPTLEDHTPPEDKPN
References
External Links
ResourceLink
Saccharomyces Genome Database QCR10
Uniprot IDP37299
Uniprot NameQCR10_YEAST
GenBank Gene IDU07275
Genebank Protein ID460251
General Reference
  • Brandt, U., Uribe, S., Schagger, H., Trumpower, B. L. (1994). "Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex." J Biol Chem 269:12947-12953.8175712
  • Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., et, a. l. .. (1994). "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Science 265:2077-2082.8091229
  • Geier, B. M., Schagger, H., Brandt, U., Colson, A. M., Von Jagow, G. (1992). "Point mutation in cytochrome b of yeast ubihydroquinone:cytochrome-c oxidoreductase causing myxothiazol resistance and facilitated dissociation of the iron-sulfur subunit." Eur J Biochem 208:375-380.1325905
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106