Protein phosphatase 2C homolog 1 (P35182)

Identification
NameProtein phosphatase 2C homolog 1
Synonyms
  • PP2C-1
Gene NamePTC1
Enzyme ClassNot Available
Biological Properties
General FunctiontRNA splicing, via endonucleolytic cleavage and ligation
Specific FunctionIt has a serine and a weak tyrosine phosphatase activity with ratios of serine to tyrosine phosphatase activity as high as 200:1. It is essential for growth or germination at 37 degrees Celsius. May have a role in the heat shock response. Involved in tRNA splicing and cell separation.
Cellular LocationNot Available
SMPDB Pathways
Stress-activated signalling pathways: high osmolarity test 1PW002773 ThumbThumb?image type=greyscaleThumb?image type=simple
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
tRNA splicing, via endonucleolytic cleavage and ligation
metal ion binding
pheromone-dependent signal transduction involved in conjugation with cellular fusion
nucleus
cytoplasm
protein serine/threonine phosphatase activity
protein dephosphorylation
inactivation of MAPK activity involved in osmosensory signaling pathway
mitochondrion inheritance
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>846 bp ATGAGTAATCATTCTGAAATCTTAGAAAGGCCAGAAACACCATATGACATAACTTATAGA GTAGGTGTGGCGGAAAATAAAAACTCGAAATTTCGGAGGACAATGGAAGATGTTCATACG TATGTTAAAAACTTTGCTTCAAGATTAGATTGGGGATATTTCGCGGTGTTTGATGGACAT GCTGGGATTCAGGCCTCCAAATGGTGTGGTAAACATCTTCATACAATTATAGAGCAAAAC ATTTTGGCAGATGAAACACGAGATGTTAGAGATGTATTGAACGATTCATTCCTAGCCATT GACGAAGAAATTAATACAAAACTTGTAGGAAATAGTGGATGTACTGCTGCTGTTTGCGTA TTACGTTGGGAGCTTCCGGATTCAGTTTCTGATGATTCAATGGATTTAGCCCAACACCAA AGAAAGTTATATACAGCAAATGTTGGTGATTCTCGAATAGTATTGTTTAGAAACGGGAAC AGCATAAGACTGACTTATGATCATAAGGCATCTGACACTTTGGAGATGCAGAGAGTTGAA CAAGCAGGTGGCCTGATAATGAAAAGTCGTGTAAATGGTATGCTGGCAGTGACGAGATCG TTAGGGGATAAATTTTTTGATAGTTTAGTAGTGGGCAGCCCATTTACCACGAGCGTAGAA ATAACTTCTGAGGACAAATTTTTAATCCTAGCGTGTGATGGATTATGGGATGTTATTGAT GATCAAGATGCATGCGAATTAATCAAGGATATTACTGAACCTAATGAAGCTGCAAAAGTC TTGGTTAGATATGCTTTGGAAAATGGCACAACAGATAATGTAACGGTCATGGTTGTCTTC CTCTAA
Protein Properties
Pfam Domain FunctionNot Available
Protein Residues281
Protein Molecular Weight31549.28
Protein Theoretical pINot Available
Signalling RegionsNot Available
Transmembrane RegionsNot Available
Protein Sequence>Protein phosphatase 2C homolog 1 MSNHSEILERPETPYDITYRVGVAENKNSKFRRTMEDVHTYVKNFASRLDWGYFAVFDGH AGIQASKWCGKHLHTIIEQNILADETRDVRDVLNDSFLAIDEEINTKLVGNSGCTAAVCV LRWELPDSVSDDSMDLAQHQRKLYTANVGDSRIVLFRNGNSIRLTYDHKASDTLEMQRVE QAGGLIMKSRVNGMLAVTRSLGDKFFDSLVVGSPFTTSVEITSEDKFLILACDGLWDVID DQDACELIKDITEPNEAAKVLVRYALENGTTDNVTVMVVFL
References
External Links
ResourceLink
Saccharomyces Genome Database PTC1
Uniprot IDP35182
Uniprot NamePTC1
General ReferenceNot Available