Cytochrome c oxidase subunit 6A, mitochondrial (P32799)

Identification
NameCytochrome c oxidase subunit 6A, mitochondrial
Synonyms
  • Cytochrome c oxidase polypeptide VIa
Gene NameCOX13
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in cytochrome-c oxidase activity
Specific FunctionNot necessary for assembly of the enzyme complex but interacts with ATP and thereby modulates the enzyme activity
Cellular LocationMitochondrion inner membrane
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Component
membrane
membrane part
mitochondrial membrane part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
mitochondrial respiratory chain complex IV
cell part
Function
catalytic activity
oxidoreductase activity
heme-copper terminal oxidase activity
cytochrome-c oxidase activity
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>390 bp ATGTTTAGACAGTGTGCTAAGAGATATGCATCTTCATTACCCCCAAATGCTTTGAAACCT GCATTTGGCCCACCAGATAAAGTGGCAGCTCAAAAATTTAAAGAATCATTAATGGCCACT GAAAAGCATGCGAAGGACACATCTAATATGTGGGTTAAAATCTCAGTTTGGGTCGCCCTA CCAGCAATTGCTTTAACAGCTGTGAACACATACTTTGTTGAAAAGGAGCATGCTGAGCAT CGTGAACATTTGAAACATGTGCCAGACTCCGAATGGCCAAGGGATTACGAGTTTATGAAT ATCAGGTCTAAGCCTTTTTTCTGGGGTGACGGTGATAAGACATTATTCTGGAATCCTGTT GTCAACAGGCACATCGAGCACGACGATTAA
Protein Properties
Pfam Domain Function
Protein Residues129
Protein Molecular Weight15021.0
Protein Theoretical pI8.49
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Cytochrome c oxidase subunit 6A, mitochondrial MFRQCAKRYASSLPPNALKPAFGPPDKVAAQKFKESLMATEKHAKDTSNMWVKISVWVAL PAIALTAVNTYFVEKEHAEHREHLKHVPDSEWPRDYEFMNIRSKPFFWGDGDKTLFWNPV VNRHIEHDD
References
External Links
ResourceLink
Saccharomyces Genome Database COX13
Uniprot IDP32799
Uniprot NameCOX13_YEAST
GenBank Gene IDAY558489
Genebank Protein ID45270868
General Reference
  • Taanman, J. W., Capaldi, R. A. (1993). "Subunit VIa of yeast cytochrome c oxidase is not necessary for assembly of the enzyme complex but modulates the enzyme activity. Isolation and characterization of the nuclear-coded gene." J Biol Chem 268:18754-18761.8395517
  • Coglievina, M., Klima, R., Bertani, I., Delneri, D., Zaccaria, P., Bruschi, C. V. (1997). "Sequencing of a 40.5 kb fragment located on the left arm of chromosome VII from Saccharomyces cerevisiae." Yeast 13:55-64.9046087
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Hu, Y., Rolfs, A., Bhullar, B., Murthy, T. V., Zhu, C., Berger, M. F., Camargo, A. A., Kelley, F., McCarron, S., Jepson, D., Richardson, A., Raphael, J., Moreira, D., Taycher, E., Zuo, D., Mohr, S., Kane, M. F., Williamson, J., Simpson, A., Bulyk, M. L., Harlow, E., Marsischky, G., Kolodner, R. D., LaBaer, J. (2007). "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Genome Res 17:536-543.17322287
  • Taanman, J. W., Capaldi, R. A. (1992). "Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme." J Biol Chem 267:22481-22485.1331058
  • Geier, B. M., Schagger, H., Ortwein, C., Link, T. A., Hagen, W. R., Brandt, U., Von Jagow, G. (1995). "Kinetic properties and ligand binding of the eleven-subunit cytochrome-c oxidase from Saccharomyces cerevisiae isolated with a novel large-scale purification method." Eur J Biochem 227:296-302.7851399