Identification
NameAcyl-CoA-binding protein
Synonyms
  • ACBP
Gene NameACB1
Enzyme ClassNot Available
Biological Properties
General FunctionInvolved in acyl-CoA binding
Specific FunctionBinds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters
Cellular LocationNot Available
SMPDB PathwaysNot Available
KEGG PathwaysNot Available
SMPDB ReactionsNot Available
KEGG ReactionsNot Available
Metabolites
YMDB IDNameView
GO Classification
Function
binding
lipid binding
fatty acid binding
acyl-CoA binding
Gene Properties
Chromosome LocationNot Available
Locus
Gene Sequence>264 bp ATGGTTTCCCAATTATTCGAAGAAAAAGCTAAAGCCGTCAACGAGCTACCAACGAAGCCC TCCACTGATGAATTATTAGAGTTGTATGCTCTGTACAAGCAAGCCACTGTAGGTGACAAC GACAAGGAAAAGCCTGGTATTTTCAACATGAAGGACCGCTACAAGTGGGAAGCCTGGGAA AACTTAAAAGGTAAATCCCAGGAAGATGCCGAAAAGGAATACATTGCCCTTGTTGATCAA CTGATTGCCAAGTACTCCTCTTAG
Protein Properties
Pfam Domain Function
Protein Residues87
Protein Molecular Weight10061.2998
Protein Theoretical pI4.56
PDB Fileshow
Signalling Regions
  • None
Transmembrane Regions
  • None
Protein Sequence>Acyl-CoA-binding protein MVSQLFEEKAKAVNELPTKPSTDELLELYALYKQATVGDNDKEKPGIFNMKDRYKWEAWE NLKGKSQEDAEKEYIALVDQLIAKYSS
References
External Links
ResourceLink
Saccharomyces Genome Database ACB1
Uniprot IDP31787
Uniprot NameACBP_YEAST
GenBank Gene IDDQ115390
Genebank Protein ID71064025
PDB ID
1ST7
General Reference
  • Rose, T. M., Schultz, E. R., Todaro, G. J. (1992). "Molecular cloning of the gene for the yeast homolog (ACB) of diazepam binding inhibitor/endozepine/acyl-CoA-binding protein." Proc Natl Acad Sci U S A 89:11287-11291.1454809
  • Borsting, C., Hummel, R., Schultz, E. R., Rose, T. M., Pedersen, M. B., Knudsen, J., Kristiansen, K. (1997). "Saccharomyces carlsbergensis contains two functional genes encoding the acyl-CoA binding protein, one similar to the ACB1 gene from S. cerevisiae and one identical to the ACB1 gene from S. monacensis." Yeast 13:1409-1421.9434347
  • Deutschbauer, A. M., Davis, R. W. (2005). "Quantitative trait loci mapped to single-nucleotide resolution in yeast." Nat Genet 37:1333-1340.16273108
  • Rieger, M., Bruckner, M., Schafer, M., Muller-Auer, S. (1997). "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII." Yeast 13:1077-1090.9290212
  • Tettelin, H., Agostoni Carbone, M. L., Albermann, K., Albers, M., Arroyo, J., Backes, U., Barreiros, T., Bertani, I., Bjourson, A. J., Bruckner, M., Bruschi, C. V., Carignani, G., Castagnoli, L., Cerdan, E., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Defoor, E., Del Bino, S., Delius, H., Delneri, D., de Wergifosse, P., Dujon, B., Kleine, K., et, a. l. .. (1997). "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Nature 387:81-84.9169869
  • Ghaemmaghami, S., Huh, W. K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., Weissman, J. S. (2003). "Global analysis of protein expression in yeast." Nature 425:737-741.14562106
  • Teilum, K., Thormann, T., Caterer, N. R., Poulsen, H. I., Jensen, P. H., Knudsen, J., Kragelund, B. B., Poulsen, F. M. (2005). "Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles." Proteins 59:80-90.15690348